Angiomyolipoma differential diagnosis

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Faizan Sheraz, M.D. [2],Rekha, M.D.

Overview

Angiomyolipoma must be differentiated from the following:^[1]^[2]


Differential diagnosis	Characteristic features of the differential diagnosis

Retroperitoneal liposarcoma	Presence of a large vessel extending into the renal cortex suggestive of angiomyolipoma; liposarcoma is hypovascular Renal parenchymal defect at the site of tumour contact favours exophytic angiomyolipoma- claw sign Calcifications suggest liposarcoma
Renal cell carcinoma	May contain fat Lipid necrosis Osseous metaplasia
Oncocytoma	May contain fat
Wilm's tumor	May contain fat
Retroperitoneal sarcoma	Liposarcoma Leiomyosarcoma
Renal cell carcinoma	Sarcomatoid differentiation
Renal leiomyoma	Very rare Desmin +ve HMB-45 -ve
Perirenal fat entrapment	Renal junctional parenchymal defect
Adrenal myelolipoma	Fat in renal parenchyma

↑ ^1.0 ^1.1 Patil, PA.; McKenney, JK.; Trpkov, K.; Hes, O.; Montironi, R.; Scarpelli, M.; Nesi, G.; Aron, M.; Sangoi, AR. (2014). "Renal Leiomyoma: A Contemporary Multi-institution Study of an Infrequent and Frequently Misclassified Neoplasm". Am J Surg Pathol. doi:10.1097/PAS.0000000000000354. PMID 25517956. Unknown parameter |month= ignored (help)
↑ ^2.0 ^2.1 Renal angiomyolipoma differential diagnosis. Dr Matt A. Morgan and Dr Behrang Amini et al. Radiopaedia 2015. http://radiopaedia.org/articles/renal-angiomyolipoma