Amyloidosis physical examination

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Amyloidosis Microchapters

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Patient Information

Overview

Historical Perspective

Classification

Primary amyloidosis
Secondary amyloidosis
Familial amyloidosis
Wild-type (senile) amyloidosis
Cardiac amyloidosis
Beta-2 microglobulin related amyloidosis
Gelsolin related amyloidosis
Lysozyme amyloid related amyloidosis
Leucocyte cell-derived chemotaxin 2 related amyloidosis
Fibrinogen A alpha-chain associated amyloidosis

Pathophysiology

Causes

Differentiating Amyloidosis from other Diseases

Epidemiology and Demographics

Risk Factors

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Natural History, Complications and Prognosis

Diagnosis

Diagnostic Study of Choice

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Case #1

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Jesus Rosario Hernandez, M.D. [2]

Overview

Common findings in amyloidosis include petechiae, ecchymosis, parotid gland enlargement, increased intraocular pressure, enlarged tongue, hepatomegaly, carpal tunnel syndrome, and Raynaud's phenomenon.

Physical Examination

Vitals

Skin

  • The most common skin findings are
    • Petechiae (small red blood spots).
    • Ecchymoses (small, flat blood spots that are round or irregular shape and bluish/purplish in colour)
    • Waxy papular nodules can be seen around the eye lids, neck and also in the groin.
    • Brittle nails.
    • Edema due to heart failure
    • Patches of hair loss can be seen.

Head

Ear

Eyes

  • Raised intraocular pressure may be present.

Throat

Abdomen

Extremities


References

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