Amyloidosis physical examination: Difference between revisions
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==Physical Examination== | ==Physical Examination== | ||
=== | ===Appearance of the Patient=== | ||
*Patients with amyloidosis usually appear normal. | |||
===Vital signs=== | |||
* [[Hypertension]] | * [[Hypertension]] | ||
* [[Tachycardia]] | * [[Tachycardia]] | ||
===Skin=== | ===Skin=== | ||
* [[Petechiae]] (small red blood spots) | |||
* [[Ecchymoses]] (small, flat blood spots that are round or irregular shape and bluish/purplish in colour) | |||
* Waxy papular nodules can be seen around the eye lids, neck and also in the groin | |||
* Brittle nails. | |||
* Edema due to [[heart failure]] | |||
* Patches of [[hair loss]] | |||
*Nail dystrophy | *Nail dystrophy | ||
*Cutis laxa<ref name="pmid267192344">{{cite journal |vauthors=Wechalekar AD, Gillmore JD, Hawkins PN |title=Systemic amyloidosis |journal=Lancet |volume=387 |issue=10038 |pages=2641–2654 |date=June 2016 |pmid=26719234 |doi=10.1016/S0140-6736(15)01274-X |url=}}</ref> | *Cutis laxa<ref name="pmid267192344">{{cite journal |vauthors=Wechalekar AD, Gillmore JD, Hawkins PN |title=Systemic amyloidosis |journal=Lancet |volume=387 |issue=10038 |pages=2641–2654 |date=June 2016 |pmid=26719234 |doi=10.1016/S0140-6736(15)01274-X |url=}}</ref> | ||
=== | ===HEENT=== | ||
* [[Parotid gland]] enlargement | * [[Parotid gland]] enlargement | ||
* Submandibular gland enlargement | * Submandibular gland enlargement | ||
*Peri-orbital purpura<ref name="pmid267192344">{{cite journal |vauthors=Wechalekar AD, Gillmore JD, Hawkins PN |title=Systemic amyloidosis |journal=Lancet |volume=387 |issue=10038 |pages=2641–2654 |date=June 2016 |pmid=26719234 |doi=10.1016/S0140-6736(15)01274-X |url=}}</ref> | |||
* Raised intraocular pressure may be present. | |||
* [[Enlarged tongue]] | |||
*Macroglossia<ref name="pmid267192344">{{cite journal |vauthors=Wechalekar AD, Gillmore JD, Hawkins PN |title=Systemic amyloidosis |journal=Lancet |volume=387 |issue=10038 |pages=2641–2654 |date=June 2016 |pmid=26719234 |doi=10.1016/S0140-6736(15)01274-X |url=}}</ref> | |||
<gallery> | <gallery> | ||
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</gallery> | </gallery> | ||
=== | ===Neck=== | ||
* | * Neck examination of patients with amyloidosis is usually normal. | ||
===Lungs=== | |||
* Pulmonary examination of patients with amyloidosis is usually normal. | |||
=== | ===Heart=== | ||
* | * Cardiovascular examination of patients with amyloidosis is usually normal. | ||
===Abdomen=== | ===Abdomen=== | ||
* [[Hepatomegaly]] | * [[Hepatomegaly]] | ||
===Back=== | |||
* Back examination of patients with amyloidosis is usually normal. | |||
===Genitourinary=== | |||
* Genitourinary examination of patients with amyloidosis is usually normal. | |||
===Neuromuscular=== | |||
* Neuromuscular examination of patients with amyloidosis is usually normal. | |||
===Extremities=== | ===Extremities=== |
Revision as of 15:41, 30 October 2019
Amyloidosis Microchapters |
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Amyloidosis physical examination On the Web |
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Risk calculators and risk factors for Amyloidosis physical examination |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Jesus Rosario Hernandez, M.D. [2]
Overview
Common findings in amyloidosis include petechiae, ecchymosis, parotid gland enlargement, increased intraocular pressure, enlarged tongue, hepatomegaly, carpal tunnel syndrome, and Raynaud's phenomenon.
Physical Examination
Appearance of the Patient
- Patients with amyloidosis usually appear normal.
Vital signs
Skin
- Petechiae (small red blood spots)
- Ecchymoses (small, flat blood spots that are round or irregular shape and bluish/purplish in colour)
- Waxy papular nodules can be seen around the eye lids, neck and also in the groin
- Brittle nails.
- Edema due to heart failure
- Patches of hair loss
- Nail dystrophy
- Cutis laxa[1]
HEENT
- Parotid gland enlargement
- Submandibular gland enlargement
- Peri-orbital purpura[1]
- Raised intraocular pressure may be present.
- Enlarged tongue
- Macroglossia[1]
Neck
- Neck examination of patients with amyloidosis is usually normal.
Lungs
- Pulmonary examination of patients with amyloidosis is usually normal.
Heart
- Cardiovascular examination of patients with amyloidosis is usually normal.
Abdomen
Back
- Back examination of patients with amyloidosis is usually normal.
Genitourinary
- Genitourinary examination of patients with amyloidosis is usually normal.
Neuromuscular
- Neuromuscular examination of patients with amyloidosis is usually normal.
Extremities
- Carpal tunnel syndrome
- Numbness of the fingers and toes
- Raynaud phenomenon
Macular Amyloidosis
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Macular Amyloidosis
Adapted from Dermatology Atlas -
Macular Amyloidosis
Adapted from Dermatology Atlas -
Macular Amyloidosis
Adapted from Dermatology Atlas -
Macular Amyloidosis
Adapted from Dermatology Atlas -
Macular Amyloidosis
Adapted from Dermatology Atlas
Nodular Amyloidosis
-
Nodular Amyloidosis
Adapted from Dermatology Atlas -
Nodular Amyloidosis
Adapted from Dermatology Atlas -
Nodular Amyloidosis
Adapted from Dermatology Atlas -
Nodular Amyloidosis
Adapted from Dermatology Atlas