Amphotericin B liposomal indications and usage: Difference between revisions
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*:Empirical therapy for presumed fungal infection in febrile, [[Febrile neutropenia|neutropenic fever]] patients. | *:Empirical therapy for presumed fungal infection in febrile, [[Febrile neutropenia|neutropenic fever]] patients. | ||
*:Treatment of [[cryptococcal meningitis]] in [[HIV]] infected patients. | *:Treatment of [[cryptococcus|cryptococcal]] [[meningitis]] in [[HIV]] infected patients. | ||
*:Treatment of patients with [[Aspergillus]] species, Candida species and/or [[Cryptococcus]] species infections (see above for the treatment of Cryptococcal Meningitis) refractory to amphotericin B deoxycholate, or in patients where renal impairment or unacceptable toxicity precludes the use of amphotericin B deoxycholate. | *:Treatment of patients with [[Aspergillus]] species, [[Candida]] species and/or [[Cryptococcus]] species infections (see above for the treatment of Cryptococcal Meningitis) refractory to amphotericin B deoxycholate, or in patients where renal impairment or unacceptable toxicity precludes the use of amphotericin B deoxycholate. | ||
*:Treatment of [[visceral leishmaniasis]]. In immunocompromised patients with visceral leishmaniasis treated with AmBisome, relapse rates were high following initial clearance of parasites.<ref name="dailymed.nlm.nih.gov">{{Cite web | last = | first = | title = AMBISOME (AMPHOTERICIN B) INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION [ASTELLAS PHARMA US, INC.] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=f7be6506-4d20-401e-a0ff-02ad7c33158a | publisher = | date = | accessdate = }}</ref> | *:Treatment of [[visceral leishmaniasis]]. In immunocompromised patients with visceral leishmaniasis treated with AmBisome, relapse rates were high following initial clearance of parasites.<ref name="dailymed.nlm.nih.gov">{{Cite web | last = | first = | title = AMBISOME (AMPHOTERICIN B) INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION [ASTELLAS PHARMA US, INC.] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=f7be6506-4d20-401e-a0ff-02ad7c33158a | publisher = | date = | accessdate = }}</ref> | ||
Latest revision as of 05:16, 12 January 2014
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Zaghw, M.D. [2]
Indications and Usage
AmBisome is indicated for the following:
- Empirical therapy for presumed fungal infection in febrile, neutropenic fever patients.
- Treatment of cryptococcal meningitis in HIV infected patients.
- Treatment of patients with Aspergillus species, Candida species and/or Cryptococcus species infections (see above for the treatment of Cryptococcal Meningitis) refractory to amphotericin B deoxycholate, or in patients where renal impairment or unacceptable toxicity precludes the use of amphotericin B deoxycholate.
- Treatment of visceral leishmaniasis. In immunocompromised patients with visceral leishmaniasis treated with AmBisome, relapse rates were high following initial clearance of parasites.[1]
References
Adapted from the FDA Package Insert.