Alzheimer's disease MRI: Difference between revisions

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*Multiple white matter T2 hyperintense regions are suggestive of chronic small vessel ischemic change.  
*Multiple white matter T2 hyperintense regions are suggestive of chronic small vessel ischemic change.  


[[image:MRI_-_alzheimer-disease-T1.jpg|thumb|250px|left|MRI - Alzheimer's Disease - T1, Case courtesy of A.Prof Frank Gaillard, <a href="https://radiopaedia.org/">Radiopaedia.org</a>. From the case <a href="https://radiopaedia.org/cases/10738">rID: 10738</a>]]
[[image:MRI_-_alzheimer-disease-T1.jpg|thumb|350px|center|MRI - Alzheimer's Disease - T1, Case courtesy of A.Prof Frank Gaillard, <a href="https://radiopaedia.org/">Radiopaedia.org</a>. From the case <a href="https://radiopaedia.org/cases/10738">rID: 10738</a>]]


[[image:MRI_-_alzheimer-disease-FLAIR.jpg|thumb|250px|center|MRI - Alzheimer's Disease - FLAIR, Case courtesy of A.Prof Frank Gaillard, <a href="https://radiopaedia.org/">Radiopaedia.org</a>. From the case <a href="https://radiopaedia.org/cases/10738">rID: 10738</a>]]
[[image:MRI_-_alzheimer-disease-FLAIR.jpg|thumb|350px|center|MRI - Alzheimer's Disease - FLAIR, Case courtesy of A.Prof Frank Gaillard, <a href="https://radiopaedia.org/">Radiopaedia.org</a>. From the case <a href="https://radiopaedia.org/cases/10738">rID: 10738</a>]]


==References==
==References==

Revision as of 20:52, 20 September 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

There are no MRI findings associated with [disease name].

OR

[Location] MRI may be helpful in the diagnosis of [disease name]. Findings on MRI suggestive of/diagnostic of [disease name] include [finding 1], [finding 2], and [finding 3].

OR

There are no MRI findings associated with [disease name]. However, a MRI may be helpful in the diagnosis of complications of [disease name], which include [complication 1], [complication 2], and [complication 3].

MRI

  • Structural MRI of the brain may be helpful in the diagnosis of alzheimer's disease. Characteristic finding on MRI suggestive of alzheimer's disease include: [1] [2] [3]
    • Reduced hippocampal volume
    • Medial temporal lobe atrophy
  • Findings on MRI in an elderly patient with memory loss demonstrates cerebral volume loss, particularly pronounced in the temporal and parietal lobes, consistent with the clinical impression of Alzheimer disease.
  • Multiple white matter T2 hyperintense regions are suggestive of chronic small vessel ischemic change.
MRI - Alzheimer's Disease - T1, Case courtesy of A.Prof Frank Gaillard, <a href="https://radiopaedia.org/">Radiopaedia.org</a>. From the case <a href="https://radiopaedia.org/cases/10738">rID: 10738</a>
MRI - Alzheimer's Disease - FLAIR, Case courtesy of A.Prof Frank Gaillard, <a href="https://radiopaedia.org/">Radiopaedia.org</a>. From the case <a href="https://radiopaedia.org/cases/10738">rID: 10738</a>

References

  1. Whitwell JL, Dickson DW, Murray ME, Weigand SD, Tosakulwong N, Senjem ML; et al. (2012). "Neuroimaging correlates of pathologically defined subtypes of Alzheimer's disease: a case-control study". Lancet Neurol. 11 (10): 868–77. doi:10.1016/S1474-4422(12)70200-4. PMC 3490201. PMID 22951070.
  2. Brook RH (1992). "Improving practice: the clinician's role". Br J Surg. 79 (7): 606–7. PMID 1643466.
  3. Barkhof F, Polvikoski TM, van Straaten EC, Kalaria RN, Sulkava R, Aronen HJ; et al. (2007). "The significance of medial temporal lobe atrophy: a postmortem MRI study in the very old". Neurology. 69 (15): 1521–7. doi:10.1212/01.wnl.0000277459.83543.99. PMID 17923614.

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