Actinomycosis

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Actinomycosis
A patient with Actinomycosis on the right side of the face.
This page is about clinical aspects of the disease.  For microbiologic aspects of the causative organism(s), see Actinomyces israelii.
 DiseasesDB     = 145 |
 ICD10          = A42 |
 ICD9           = 039 |
 ICDO           = |
 OMIM           = |
 MedlinePlus    = |
 MeshID         = D000196 |

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Actinomycosis Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Actinomycosis from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

Chest X Ray

CT

MRI

Echocardiography or Ultrasound

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Actinomycosis On the Web

Most recent articles

cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Actinomycosis

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Actinomycosis

CDC on Actinomycosis

Actinomycosis in the news

Blogs on Actinomycosis

to Hospitals Treating Actinomycosis

Risk calculators and risk factors for Actinomycosis

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Synonyms and keywords: Actinomyces; actinomyces israeli;

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Actinomycosis from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms | Physical Examination | Laboratory Findings | Electrocardiogram | X Ray | CT | MRI | Echocardiography or Ultrasound | Other Imaging Findings | Other Diagnostic Studies

Treatment

Medical therapy | Surgery | Primary Prevention | Secondary Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies

  • Actinomyces species including A. israeli[1]
  • Preferred regimen: Penicillin 3-4 million units IV q4h for 2-6 weeks THEN Penicillin V 2-4 g/day PO qid for 6-12 months
  • Alternative regimen (1): Erythromycin 500-1000 mg IV q6h OR 500 mg PO qid
  • Alternative regimen (2): Tetracyclin 500 mg PO qid
  • Alternative regimen (3): Doxycycline 100 mg IV q12h OR 100 mg PO bid
  • Alternative regimen (4): Clindamycin 900 mg IV q8h OR 300-450 mg PO qd
  • Alternative regimen (5): Minocycline 100 mg IV q12h OR 100 mg PO bid

Acknowledgements

The content on this page was first contributed by: Dr. Steve Wiviott


References

  1. Bennett, John (2015). Mandell, Douglas, and Bennett's principles and practice of infectious diseases. Philadelphia, PA: Elsevier/Saunders. ISBN 978-1455748013.


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