Acoustic neuroma epidemiology and demographics: Difference between revisions

	Acoustic neuroma Microchapters
Home
Patient Information
Overview
Historical Perspective
Classification
Pathophysiology
Causes
Differentiating Acoustic neuroma from other Diseases
Epidemiology and Demographics
Risk Factors
Screening
Natural History, Complications and Prognosis
Diagnosis
Diagnostic Study of Choice
History and Symptoms
Physical Examination
Laboratory Findings
Electrocardiogram
X-ray
Echocardiography or Ultrasound
CT
MRI
Other Imaging Findings
Other Diagnostic Studies
Treatment
Medical Therapy
Surgery
Primary Prevention
Secondary Prevention
Cost-Effectiveness of Therapy
Future or Investigational Therapies
Case Studies
Case #1
Acoustic neuroma epidemiology and demographics On the Web
Most recent articles
cited articles
Review articles
CME Programs
Powerpoint slides
Images
American Roentgen Ray Society Images of Acoustic neuroma epidemiology and demographics All Images X-rays Echo & Ultrasound CT Images MRI
Ongoing Trials at Clinical Trials.gov
US National Guidelines Clearinghouse
NICE Guidance
FDA on Acoustic neuroma epidemiology and demographics
CDC on Acoustic neuroma epidemiology and demographics
Acoustic neuroma epidemiology and demographics in the news
Blogs on Acoustic neuroma epidemiology and demographics
Directions to Hospitals Treating Acoustic neuroma
Risk calculators and risk factors for Acoustic neuroma epidemiology and demographics

VisualWikitext

Latest revision as of 17:59, 24 April 2019

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Simrat Sarai, M.D. [2] Mohsen Basiri M.D.Sabawoon Mirwais, M.B.B.S, M.D.[3]

Overview

The incidence of acoustic neuroma ranges from 0.3 to 1 per 100, 000 individuals. The prevalence of acoustic neuroma is approximately 0.2 per 100,000 individuals. Women are more commonly affected by acoustic neuroma than men. Most cases of acoustic neuroma develop in individuals between 30 and 60 years of age.

Epidemiology and Demographics

Acoustic neuroma accounts for 7 - 8% of all primary intracranial tumors and 75 - 90% of cerebellopontine angle masses. Bilateral vestibular schwannomas are highly suggestive of neurofibromatosis type 2 (NF2), although bilateral tumors are encountered in the familial form of acoustic schwannomas in the absence of other stigmata of NF2.^[1]^[2]^[3]

Age-adjusted incidence rates across demographic variables
demographic variables		Rate (per 100,000)
Gender	Male	1.1
Gender	Female	1.0
Race	White	1.1
	Black	0.4
	Other	1.3
Age (yrs), all	<20	0.1
	20-39	0.6
	40-49	1.5
	50-64	2.7
	65+	2.0
Age (yrs), Male	<20	0
	20-39	0.5
	40-49	1.6
	50-64	2.6
	65+	2.4
Age (yrs), Female	<20	0.1
	20-39	0.7
	40-49	1.3
	50-64	2.8
	65+	1.7

Incidence

The incidence of acoustic neuroma ranges from 0.3 to 1 per 100, 000 individuals.^[4]^[5]^[6]^[7]

Prevalence

The prevalence of acoustic neuroma is approximately 0.2 per 100,000 individuals.^[8]

Mortality rate

The in-hospital mortality rate of surgery for acoustic neuroma in the United States is 0.5%.^[9]

Age

Most cases of acoustic neuroma develop in individuals between the ages of 30 and 60.
Although quite rare, they can also develop in children.^[10]

Gender

Acoustic neuroma can affect women more often than men.^[11]

References

↑ Acoustic Schwannoma. Radiopedia(2015) http://radiopaedia.org/articles/acoustic-schwannoma Accessed on October 2 2015
↑ Thomas J. Gal, MD, MPH, Jennifer Shinn, PhD, and Bin Huang, PhD, Lexington, KY (2010). "Current epidemiology and management trends in acoustic neuroma". Otolaryngology–Head and Neck Surgery.
↑ Acoustic neuroma. Medline Plus(2015) https://www.nlm.nih.gov/medlineplus/ency/article/000778.htm Accessed on October 2 2015
↑ Doris Lin, Joseph L. Hegarty, Nancy J. Fischbein & Robert K. Jackler (2005). "The prevalence of "incidental" acoustic neuroma". Archives of otolaryngology--head & neck surgery. 131 (3): 241–244. doi:10.1001/archotol.131.3.241. PMID 15781765. Unknown parameter |month= ignored (help)
↑ M. Tos & J. Thomsen (1984). "Epidemiology of acoustic neuromas". The Journal of laryngology and otology. 98 (7): 685–692. PMID 6747450. Unknown parameter |month= ignored (help)
↑ M. F. Howitz, C. Johansen, M. Tos, S. Charabi & J. H. Olsen (2000). "Incidence of vestibular schwannoma in Denmark, 1977-1995". The American journal of otology. 21 (5): 690–694. PMID 10993460. Unknown parameter |month= ignored (help)
↑ {{Cite journal | author = R. Y. Seedat, A. J. Claassen & D. A. Mol | title = Incidence and management of acoustic neuromas in South Africa | journal = [[Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology]] | volume = 23 | issue = 6 | pages = 996–998 | year = 2002 | month = November | pmid = 12438869 }}
↑ Doris Lin, Joseph L. Hegarty, Nancy J. Fischbein & Robert K. Jackler (2005). "The prevalence of "incidental" acoustic neuroma". Archives of otolaryngology--head & neck surgery. 131 (3): 241–244. doi:10.1001/archotol.131.3.241. PMID 15781765. Unknown parameter |month= ignored (help)
↑ McClelland, Shearwood; Kim, Ellen; Murphy, James D.; Jaboin, Jerry J. (2017). "Operative Mortality Rates of Acoustic Neuroma Surgery". Otology & Neurotology. 38 (5): 751–753. doi:10.1097/MAO.0000000000001362. ISSN 1531-7129.
↑ Xiang Huang, Jian Xu, Ming Xu, Liang-Fu Zhou, Rong Zhang, Liqin Lang, Qiwu Xu, Ping Zhong, Mingyu Chen, Ying Wang & Zhenyu Zhang (2013). "Clinical features of intracranial vestibular schwannomas". Oncology letters. 5 (1): 57–62. doi:10.3892/ol.2012.1011. PMID 23255894. Unknown parameter |month= ignored (help)
↑ Xiang Huang, Jian Xu, Ming Xu, Liang-Fu Zhou, Rong Zhang, Liqin Lang, Qiwu Xu, Ping Zhong, Mingyu Chen, Ying Wang & Zhenyu Zhang (2013). "Clinical features of intracranial vestibular schwannomas". Oncology letters. 5 (1): 57–62. doi:10.3892/ol.2012.1011. PMID 23255894. Unknown parameter |month= ignored (help)

Template:WikiDoc Sources

[radio-1] Acoustic Schwannoma. Radiopedia(2015) http://radiopaedia.org/articles/acoustic-schwannoma Accessed on October 2 2015

[2] Thomas J. Gal, MD, MPH, Jennifer Shinn, PhD, and Bin Huang, PhD, Lexington, KY (2010). "Current epidemiology and management trends in acoustic neuroma". Otolaryngology–Head and Neck Surgery.

[Medline_Plus-3] Acoustic neuroma. Medline Plus(2015) https://www.nlm.nih.gov/medlineplus/ency/article/000778.htm Accessed on October 2 2015

[4] Doris Lin, Joseph L. Hegarty, Nancy J. Fischbein & Robert K. Jackler (2005). "The prevalence of "incidental" acoustic neuroma". Archives of otolaryngology--head & neck surgery. 131 (3): 241–244. doi:10.1001/archotol.131.3.241. PMID 15781765. Unknown parameter |month= ignored (help)

[5] M. Tos & J. Thomsen (1984). "Epidemiology of acoustic neuromas". The Journal of laryngology and otology. 98 (7): 685–692. PMID 6747450. Unknown parameter |month= ignored (help)

[6] M. F. Howitz, C. Johansen, M. Tos, S. Charabi & J. H. Olsen (2000). "Incidence of vestibular schwannoma in Denmark, 1977-1995". The American journal of otology. 21 (5): 690–694. PMID 10993460. Unknown parameter |month= ignored (help)

[7] {{Cite journal | author = R. Y. Seedat, A. J. Claassen & D. A. Mol | title = Incidence and management of acoustic neuromas in South Africa | journal = [[Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology]] | volume = 23 | issue = 6 | pages = 996–998 | year = 2002 | month = November | pmid = 12438869 }}

[8] Doris Lin, Joseph L. Hegarty, Nancy J. Fischbein & Robert K. Jackler (2005). "The prevalence of "incidental" acoustic neuroma". Archives of otolaryngology--head & neck surgery. 131 (3): 241–244. doi:10.1001/archotol.131.3.241. PMID 15781765. Unknown parameter |month= ignored (help)

[McClellandKim2017-9] McClelland, Shearwood; Kim, Ellen; Murphy, James D.; Jaboin, Jerry J. (2017). "Operative Mortality Rates of Acoustic Neuroma Surgery". Otology & Neurotology. 38 (5): 751–753. doi:10.1097/MAO.0000000000001362. ISSN 1531-7129.

[10] Xiang Huang, Jian Xu, Ming Xu, Liang-Fu Zhou, Rong Zhang, Liqin Lang, Qiwu Xu, Ping Zhong, Mingyu Chen, Ying Wang & Zhenyu Zhang (2013). "Clinical features of intracranial vestibular schwannomas". Oncology letters. 5 (1): 57–62. doi:10.3892/ol.2012.1011. PMID 23255894. Unknown parameter |month= ignored (help)

[11] Xiang Huang, Jian Xu, Ming Xu, Liang-Fu Zhou, Rong Zhang, Liqin Lang, Qiwu Xu, Ping Zhong, Mingyu Chen, Ying Wang & Zhenyu Zhang (2013). "Clinical features of intracranial vestibular schwannomas". Oncology letters. 5 (1): 57–62. doi:10.3892/ol.2012.1011. PMID 23255894. Unknown parameter |month= ignored (help)

[1]

[2]

[3]

[4]

[5]

[6]

[7]

[8]

[9]

[10]

[11]

@@ Line 1: / Line 1: @@
+__NOTOC__
 {{Acoustic neuroma}}
-{{CMG}}
+{{CMG}}{{AE}}{{Simrat}} {{M.B}}{{Sab}}
 ==Overview==
+The [[incidence]] of acoustic neuroma ranges from 0.3 to 1 per 100, 000 individuals. The [[prevalence]] of acoustic neuroma is approximately 0.2 per 100,000 individuals. Women are more commonly affected by acoustic neuroma than men. Most cases of acoustic neuroma develop in individuals between 30 and 60 years of age.
-The true incidence of Acoustic neuromas has been difficult to estimate.<ref>Ho SY, Kveton JF. Acoustic neuroma assessment and management. Otolaryngol Clin North Am 2002;35:393-404</ref> <ref>Tos M, Charabi S, Thomsen J. Clincial experience with vestibular schwannomas: epidemiology, symptomatology, diagnosis, and surgical results. Eur Arch Otorhinolaryngol 1998;255:1-6.</ref>  The incidence has been reported to range from 1 to 20 per million per year.<ref> Howitz MF, Johansen C, Tos M, Charabi S, Olsen JH. Incidence of Vestibular Schwannoma in Denmark, 1977-1995. Am J Otol 2000;21:690-694</ref> <ref>Tos M, Charabi S, Thomsen J. Clincial experience with vestibular schwannomas: epidemiology, symptomatology, diagnosis, and surgical results. Eur Arch Otorhinolaryngol 1998;255:1-6.</ref> <ref>Tos M, Stangerup SE, Cayé-Thomasen P, Tos T, Thomsen J. What is the real incidence of vestibular schwannoma? Arch Otolaryngol Head Neck Surg 2004;130:216-220</ref> A study of acoustic neuromas in a review of 24,000 brain MRIs reported a prevalence of 0.07%. When comparing the clinical incidence
+==Epidemiology and Demographics==
-of acoustic neuromas to the prevalence of occult acoustic neuromas ascertained from histopathological studies of temporal bones, it can be concluded that the vast majority of tumors that exist are never clinically manifested.<ref>Thomsen J, Tos M. Acoustic neuroma: clinical aspects, audiovestibular assessment, diagnostic delay, and growth rate. Am J Otol 1990;11:12-19.</ref> <ref>Rosenberg SI. Natural history of acoustic neuromas. Laryngoscope 2000;110:497-508.</ref> Acoustic neuromas are most commonly diagnosed between the ages of 30 and 68.<ref>Strasnick B, Glasscock ME, Haynes D, McMenomey SO, Minor LB. The natural history of untreated acoustic neuromas. Laryngoscope1994;104:1115-1119.</ref> <ref>Hart RG, Davenport J. Diagnosis of acoustic neuroma. Neurosurgery 1981;9:450-463.</ref> Reported cases of acoustic neuroma in childhood are rare and in such patients other evidence of NF2 should be investigated. In a study of 146 cases of acoustic neuromas, the median age of cases was 52 years.<ref>Edwards CG, Schwartzbaum JA, Lönn S, Ahlbom A, Feychting M. Exposure to loud noise and risk of acoustic neuroma. Am J Epidemiol 2006;163:327-333.</ref> In a second study of 793 cases of Acoustic neuroma, the median age of the cases was 54 years. The sex ratio (females/males) for acoustic neuromas has been reported to be >1 <ref>Inskip PD, Tarone RE, Hatch EE, et al. Sociodemographic indicators and risk of brain tumours. Int J Epidemiol 2003;32:225-233.</ref> <ref>Howitz MF, Johansen C, Tos M, Charabi S, Olsen JH. Incidence of Vestibular Schwannoma in Denmark, 1977-1995. Am J Otol 2000;21:690-694.</ref> <ref>Chandler CL, Ramsden RT. Acoustic schwannoma. Br J Hosp Med 1993;49:336-343.</ref> <ref>Spoelhof GD. When to suspect acoustic neuroma. Am Fam Physician 1995;52:1768-1774.</ref>
+Acoustic neuroma accounts for 7 - 8% of all primary [[Cranium|intracranial]] [[tumors]] and 75 - 90% of [[cerebellopontine]] angle masses. [[Bilateral]] vestibular [[schwannomas]] are highly suggestive of [[neurofibromatosis type 2|neurofibromatosis type 2 (NF2)]], although [[bilateral]] [[tumors]] are encountered in the [[familial]] form of acoustic [[Schwannoma|schwannomas]] in the absence of other stigmata of [[Neurofibromatosis type II|NF2]].<ref name="radio">Acoustic Schwannoma. Radiopedia(2015) http://radiopaedia.org/articles/acoustic-schwannoma Accessed on October 2 2015</ref><ref>{{Cite journal|last=Thomas J. Gal, MD, MPH, Jennifer Shinn, PhD, and Bin Huang, PhD, Lexington, KY|first=|date=2010|title=Current epidemiology and management trends in acoustic neuroma|url=|journal=Otolaryngology–Head and Neck Surgery|volume=|pages=|via=}}</ref><ref name="Medline Plus">Acoustic neuroma. Medline Plus(2015) https://www.nlm.nih.gov/medlineplus/ency/article/000778.htm Accessed on October 2 2015</ref>
-However, data from the Central Brain Tumor Registry of the United States (CBTRUS) do not support a female/male difference<ref>Propp JM, McCarthy BJ, Davis FG, Preston-Martin S. Descriptive epidemiology of vestibular schwannomas. Neuro-oncol 2006;8:1-11.</ref> Nevertheless,some of the studies that analyzed Swedish data, the sex ratio (females/males) of acoustic neuromas in the Nordic counties has been shown to be >1. This sex ratio may indicate that hormones play a role in the etiology of acoustic neuromas<ref>Schlehofer B, Blettner M, Wahrendorf J. Association between brain tumors and menopausal status. J Natl Cancer Inst 1992;84:1346-1349</ref> <ref>Howitz MF, Johansen C, Tos M, Charabi S, Olsen JH. Incidence of Vestibular Schwannoma in Denmark, 1977-1995. Am J Otol 2000;21:690-694.</ref> The tumor has been reported to be higher in whites than in non-whites<ref>Propp JM, McCarthy BJ, Davis FG, Preston-Martin S. Descriptive epidemiology of vestibular schwannomas. Neuro-oncol 2006;8:1-11.</ref> as well as being uncommon in individuals of African ancestry<ref>Chandler CL, Ramsden RT. Acoustic schwannoma. Br J Hosp Med 1993;49:336-343..</ref> According to some studies the incidence of acoustic neuromas has been
-increasing. This may be due to several factors. Steady improvements in
-diagnosis, such as the introduction of auditory brainstem response, CT, and MRI could
-explain part of the increased incidence. Increased awareness among physicians
-and patients of the symptoms of acoustic neuromas may have caused an increase in the
-reporting of the tumor. Changes in classification or coding may also explain some
-of the trend, whereby registries may have misclassified nonvestibular schwannomas as
-acoustic neuromas. Or, there may be a true increase in the incidence of these
-tumors. The trend may also lend support to the emerging hypotheses regarding an
-environmental cause of these tumors. Established and hypothesized risk factors have been
-reported extensively in the literature and include ionizing radiation exposure, cellular
-telephone use, specific occupations, a possible hormonal cause, and loud noise exposure.
-<div><div><div><div>'''Average annual incidence rates, overall and by gender and race, CBTRUS (1995–1999) and LACCSP (1995–1998)'''</div></div></div></div><div>
+{| style="border: 3px; margin: 1px; font-size: 90%; width: 400px; align=" center "
-{| cellspacing="3" cellpadding="2"
+! colspan="3" style="background: #5579ff; width 400px; " | {{fontcolor|#FFF|Age-adjusted incidence rates across demographic variables}}
 |-
-| align="center" |
+! colspan="2" style="background: #4479ba; " | {{fontcolor|#FFF| demographic variables}}
-| align="center" |
+! style="background: #4479ba; " | {{fontcolor|#FFF| Rate (per 100,000)}}
-| align="center" |
+|-
-| align="center" | '''Gender'''
+! rowspan="2" style="padding: 4px 4px; background: #00AF89; " | {{fontcolor|#FFF| Gender}}
+! style="padding: 3px 3px; background: #B0E0E6; " | Male
-----
+! style="padding: 3px 3px; background: #E0FFFF; " | 1.1
-| align="center" | '''Race'''
+|-
+! style="padding: 3px 3px; background: #B0E0E6; " | Female
-----
+! style="padding: 3px 3px; background: #E0FFFF; " | 1.0
+|-
+! rowspan="3" style="padding: 4px 4px; background: #00AF89; " | {{fontcolor|#FFF| Race}}
+! style="padding: 3px 3px; background: #B0E0E6; " | White
+! style="padding: 3px 3px; background: #E0FFFF; " | 1.1
+|-
+! style="padding: 3px 3px; background: #B0E0E6; " | Black
+! style="padding: 3px 3px; background: #E0FFFF; " | 0.4
+|-
+! style="padding: 3px 3px; background: #B0E0E6; " | Other
+! style="padding: 3px 3px; background: #E0FFFF; " | 1.3
+|-
+! rowspan="5" style="padding: 3px 3px; background: #00AF89 " | {{fontcolor|#FFF| Age (yrs), all}}
+! style="padding: 3px 3px; background: #B0E0E6; " | <20
+! style="padding: 3px 3px; background: #E0FFFF; " | 0.1
+|-
+! style="padding: 3px 3px; background: #B0E0E6; " | 20-39
+! style="padding: 3px 3px; background: #E0FFFF; " | 0.6
+|-
+! style="padding: 3px 3px; background: #B0E0E6; " | 40-49
+! style="padding: 3px 3px; background: #E0FFFF; " | 1.5
+|-
+! style="padding: 3px 3px; background: #B0E0E6; " | 50-64
+! style="padding: 3px 3px; background: #E0FFFF; " | 2.7
+|-
+! style="padding: 3px 3px; background: #B0E0E6; " | 65+
+! style="padding: 3px 3px; background: #E0FFFF; " | 2.0
+|-
+! rowspan="5" style="padding: 3px 3px; background: #00AF89; " | {{fontcolor|#FFF| Age (yrs), Male}}
+! style="padding: 3px 3px; background: #B0E0E6; " | <20
+! style="padding: 3px 3px; background: #E0FFFF; " | 0
+|-
+! style="padding: 3px 3px; background: #B0E0E6; " | 20-39
+! style="padding: 3px 3px; background: #E0FFFF; " | 0.5
+|-
+! style="padding: 3px 3px; background: #B0E0E6; " | 40-49
+! style="padding: 3px 3px; background: #E0FFFF; " | 1.6
 |-
-| '''Type of Tumor'''
+! style="padding: 3px 3px; background: #B0E0E6; " | 50-64
-| align="center" | '''Total Number of Tumors (N)'''
+! style="padding: 3px 3px; background: #E0FFFF; " | 2.6
-| align="center" | '''Overall Rate (CI)'''
-| align="center" | '''Male'''
-| align="center" | '''Female'''
-| align="center" | '''White'''
-| align="center" | '''Nonwhite'''
 |-
-| colspan="7" rowspan="1" | ''CBTRUS, 1995–1999''
+! style="padding: 3px 3px; background: #B0E0E6; " | 65+
+! style="padding: 3px 3px; background: #E0FFFF; " | 2.4
 |-
-| rowspan="1" colspan="1" | Nerve sheath
+! rowspan="5" style="padding: 3px 3px; background: #00AF89; " | {{fontcolor|#FFF| Age (yrs), Female}}
-| align="center" rowspan="1" colspan="1" | 2,811
+! style="padding: 3px 3px; background: #B0E0E6; " | <20
-| align="center" rowspan="1" colspan="1" | 1.08 (1.04–1.12)
+! style="padding: 3px 3px; background: #E0FFFF; " | 0.1
-| align="center" rowspan="1" colspan="1" | 1.10 (1.04–1.16)
-| align="center" rowspan="1" colspan="1" | 1.07 (1.02–1.13)
-| align="center" rowspan="1" colspan="1" | 1.13 (1.08–1.17)
-| align="center" rowspan="1" colspan="1" | 0.56 (0.48–0.63)
 |-
-| rowspan="1" colspan="1" | Vestibular schwannoma
+! style="padding: 3px 3px; background: #B0E0E6; " | 20-39
-| align="center" rowspan="1" colspan="1" | 1,424
+! style="padding: 3px 3px; background: #E0FFFF; " | 0.7
-| align="center" rowspan="1" colspan="1" | 0.55 (0.52–0.58)
-| align="center" rowspan="1" colspan="1" | 0.56 (0.52–0.60)
-| align="center" rowspan="1" colspan="1" | 0.55 (0.51–0.58)
-| align="center" rowspan="1" colspan="1" | 0.58 (0.55–0.61)
-| align="center" rowspan="1" colspan="1" | 0.23 (0.18–0.28)
 |-
-| colspan="7" rowspan="1" | ''LACCSP, 1995–1998''
+! style="padding: 3px 3px; background: #B0E0E6; " | 40-49
+! style="padding: 3px 3px; background: #E0FFFF; " | 1.3
 |-
-| rowspan="1" colspan="1" | Nerve sheath
+! style="padding: 3px 3px; background: #B0E0E6; " | 50-64
-| align="center" rowspan="1" colspan="1" | 352
+! style="padding: 3px 3px; background: #E0FFFF; " | 2.8
-| align="center" rowspan="1" colspan="1" | 1.11 (0.99–1.22)
-| align="center" rowspan="1" colspan="1" | 1.15 (0.97–1.32)
-| align="center" rowspan="1" colspan="1" | 1.07 (0.91–1.23)
-| align="center" rowspan="1" colspan="1" | 1.21 (1.08–1.36)
-| align="center" rowspan="1" colspan="1" | 0.68 (0.50–0.87)
 |-
-| rowspan="1" colspan="1" | Vestibular schwannoma
+! style="padding: 3px 3px; background: #B0E0E6; " | 65+
-| align="center" rowspan="1" colspan="1" | 256
+! style="padding: 3px 3px; background: #E0FFFF; " | 1.7
-| align="center" rowspan="1" colspan="1" | 0.82 (0.71–0.92)
-| align="center" rowspan="1" colspan="1" | 0.83 (0.68–0.99)
-| align="center" rowspan="1" colspan="1" | (0.66–0.94)0.80
-| align="center" rowspan="1" colspan="1" | 0.89 (0.77–1.01)
-| align="center" rowspan="1" colspan="1" | 0.51 (0.36–0.67)
 |}
-</div><div><div>Rates are per 100,000 person-years and are age adjusted to the year 2000 U.S. standard population.</div><div>Abbreviations: CBTRUS, Central Brain Tumor Registry of the United States; CI, confidence interval; LACCSP, Los Angeles County Cancer Surveillance Program.</div></div>
-==References==
+===Incidence===
+The [[incidence]] of acoustic neuroma ranges from 0.3 to 1 per 100, 000 individuals.<ref>{{Cite journal
+ | author = [[Doris Lin]], [[Joseph L. Hegarty]], [[Nancy J. Fischbein]] & [[Robert K. Jackler]]
+ | title = The prevalence of "incidental" acoustic neuroma
+ | journal = [[Archives of otolaryngology--head & neck surgery]]
+ | volume = 131
+ | issue = 3
+ | pages = 241–244
+ | year = 2005
+ | month = March
+ | doi = 10.1001/archotol.131.3.241
+ | pmid = 15781765
+}}</ref><ref>{{Cite journal
+ | author = [[M. Tos]] & [[J. Thomsen]]
+ | title = Epidemiology of acoustic neuromas
+ | journal = [[The Journal of laryngology and otology]]
+ | volume = 98
+ | issue = 7
+ | pages = 685–692
+ | year = 1984
+ | month = July
+ | pmid = 6747450
+}}</ref><ref>{{Cite journal
+ | author = [[M. F. Howitz]], [[C. Johansen]], [[M. Tos]], [[S. Charabi]] & [[J. H. Olsen]]
+ | title = Incidence of vestibular schwannoma in Denmark, 1977-1995
+ | journal = [[The American journal of otology]]
+ | volume = 21
+ | issue = 5
+ | pages = 690–694
+ | year = 2000
+ | month = September
+ | pmid = 10993460
+}}</ref><ref>{{Cite journal
+<nowiki> </nowiki><nowiki>|</nowiki> author = [[R. Y. Seedat]], [[A. J. Claassen]] & [[D. A. Mol]]
+ | title = Incidence and management of acoustic neuromas in South Africa
+ | journal = [[Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology]]
+<nowiki> </nowiki><nowiki>|</nowiki> volume = 23
+<nowiki> </nowiki><nowiki>|</nowiki> issue = 6
+<nowiki> </nowiki><nowiki>|</nowiki> pages = 996–998
+<nowiki> </nowiki><nowiki>|</nowiki> year = 2002
+<nowiki> </nowiki><nowiki>|</nowiki> month = November
+<nowiki> </nowiki><nowiki>|</nowiki> pmid = 12438869
+}}</ref>
-{{reflist|2}}
+===Prevalence===
+The [[prevalence]] of acoustic neuroma is approximately 0.2 per 100,000 individuals.<ref>{{Cite journal
+ | author = [[Doris Lin]], [[Joseph L. Hegarty]], [[Nancy J. Fischbein]] & [[Robert K. Jackler]]
+ | title = The prevalence of "incidental" acoustic neuroma
+ | journal = [[Archives of otolaryngology--head & neck surgery]]
+ | volume = 131
+ | issue = 3
+ | pages = 241–244
+ | year = 2005
+ | month = March
+ | doi = 10.1001/archotol.131.3.241
+ | pmid = 15781765
+}}</ref>
+===Mortality rate===
+The in-hospital [[mortality rate]] of [[surgery]] for acoustic neuroma in the United States is 0.5%.<ref name="McClellandKim2017">{{cite journal|last1=McClelland|first1=Shearwood|last2=Kim|first2=Ellen|last3=Murphy|first3=James D.|last4=Jaboin|first4=Jerry J.|title=Operative Mortality Rates of Acoustic Neuroma Surgery|journal=Otology & Neurotology|volume=38|issue=5|year=2017|pages=751–753|issn=1531-7129|doi=10.1097/MAO.0000000000001362}}</ref>
-{{Nervous tissue tumors}}
+===Age===
+* Most cases of acoustic neuroma develop in individuals between the ages of 30 and 60.
+* Although quite rare, they can also develop in children.<ref>{{Cite journal
+ | author = [[Xiang Huang]], [[Jian Xu]], [[Ming Xu]], [[Liang-Fu Zhou]], [[Rong Zhang]], [[Liqin Lang]], [[Qiwu Xu]], [[Ping Zhong]], [[Mingyu Chen]], [[Ying Wang]] & [[Zhenyu Zhang]]
+ | title = Clinical features of intracranial vestibular schwannomas
+ | journal = [[Oncology letters]]
+ | volume = 5
+ | issue = 1
+ | pages = 57–62
+ | year = 2013
+ | month = January
+ | doi = 10.3892/ol.2012.1011
+ | pmid = 23255894
+}}</ref>
-[[de:Akustikusneurinom]]
+===Gender===
-[[fr:Neurinome#Neurinome acoustique]]
+Acoustic neuroma can affect women more often than men.<ref>{{Cite journal
-[[nl:Brughoektumor]]
+ | author = [[Xiang Huang]], [[Jian Xu]], [[Ming Xu]], [[Liang-Fu Zhou]], [[Rong Zhang]], [[Liqin Lang]], [[Qiwu Xu]], [[Ping Zhong]], [[Mingyu Chen]], [[Ying Wang]] & [[Zhenyu Zhang]]
+ | title = Clinical features of intracranial vestibular schwannomas
+ | journal = [[Oncology letters]]
+ | volume = 5
+ | issue = 1
+ | pages = 57–62
+ | year = 2013
+ | month = January
+ | doi = 10.3892/ol.2012.1011
+ | pmid = 23255894
+}}</ref>
+==References==
+{{reflist|2}}
 {{WikiDoc Help Menu}}
 {{WikiDoc Sources}}
+[[Category:Types of cancer]]
 [[Category:Disease]]
+ [[Category:Up-To-Date]]
 [[Category:Oncology]]
+[[Category:Medicine]]
+[[Category:Otolaryngology]]
 [[Category:Neurology]]
 [[Category:Neurosurgery]]
-[[Category:Otolaryngology]]
-[[Category:Types of cancer]]
-[[Category:Pathology]]


Acoustic neuroma Microchapters
Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Acoustic neuroma from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Study of Choice

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

X-ray

Echocardiography or Ultrasound


CT

MRI

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Acoustic neuroma epidemiology and demographics On the Web

Most recent articles

cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Acoustic neuroma epidemiology and demographics All Images X-rays Echo & Ultrasound CT Images MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Acoustic neuroma epidemiology and demographics

CDC on Acoustic neuroma epidemiology and demographics

Acoustic neuroma epidemiology and demographics in the news

Blogs on Acoustic neuroma epidemiology and demographics

Directions to Hospitals Treating Acoustic neuroma

Risk calculators and risk factors for Acoustic neuroma epidemiology and demographics