Abderhalden reaction

Revision as of 15:08, 9 April 2009 by Dkhabbaz (talk | contribs)
Jump to: navigation, search

WikiDoc Resources for Abderhalden reaction

Articles

Most recent articles on Abderhalden reaction

Most cited articles on Abderhalden reaction

Review articles on Abderhalden reaction

Articles on Abderhalden reaction in N Eng J Med, Lancet, BMJ

Media

Powerpoint slides on Abderhalden reaction

Images of Abderhalden reaction

Photos of Abderhalden reaction

Podcasts & MP3s on Abderhalden reaction

Videos on Abderhalden reaction

Evidence Based Medicine

Cochrane Collaboration on Abderhalden reaction

Bandolier on Abderhalden reaction

TRIP on Abderhalden reaction

Clinical Trials

Ongoing Trials on Abderhalden reaction at Clinical Trials.gov

Trial results on Abderhalden reaction

Clinical Trials on Abderhalden reaction at Google

Guidelines / Policies / Govt

US National Guidelines Clearinghouse on Abderhalden reaction

NICE Guidance on Abderhalden reaction

NHS PRODIGY Guidance

FDA on Abderhalden reaction

CDC on Abderhalden reaction

Books

Books on Abderhalden reaction

News

Abderhalden reaction in the news

Be alerted to news on Abderhalden reaction

News trends on Abderhalden reaction

Commentary

Blogs on Abderhalden reaction

Definitions

Definitions of Abderhalden reaction

Patient Resources / Community

Patient resources on Abderhalden reaction

Discussion groups on Abderhalden reaction

Patient Handouts on Abderhalden reaction

Directions to Hospitals Treating Abderhalden reaction

Risk calculators and risk factors for Abderhalden reaction

Healthcare Provider Resources

Symptoms of Abderhalden reaction

Causes & Risk Factors for Abderhalden reaction

Diagnostic studies for Abderhalden reaction

Treatment of Abderhalden reaction

Continuing Medical Education (CME)

CME Programs on Abderhalden reaction

International

Abderhalden reaction en Espanol

Abderhalden reaction en Francais

Business

Abderhalden reaction in the Marketplace

Patents on Abderhalden reaction

Experimental / Informatics

List of terms related to Abderhalden reaction

Please Take Over This Page and Apply to be Editor-In-Chief for this topic: There can be one or more than one Editor-In-Chief. You may also apply to be an Associate Editor-In-Chief of one of the subtopics below. Please mail us [1] to indicate your interest in serving either as an Editor-In-Chief of the entire topic or as an Associate Editor-In-Chief for a subtopic. Please be sure to attach your CV and or biographical sketch.

The Abderhalden reaction is a now defunct blood test for pregnancy developed by Emil Abderhalden.

In 1909 Abderhalden found that on identification of a foreign protein in the blood, the body reacts with a "defensive fermentation" (in modern terms, a protease reaction) that causes disintegration of the protein. He developed the test in 1912. This test was apparently contentious soon after its development and a significant body of work was published both in support of and refuting the test's reliability. One such publication concluded "...the individual variations of both pregnant and non-pregnant sera make the results from both overlap so completely as to render the reaction, even with quantitative technique, absolutely indecisive for either positive or negative diagnosis of pregnancy." (Van Slyke et al. 1915). The test's overall unreliability led to its being superseded in 1928 by the Aschheim-Zondek test. Due to Abderhalden's high reputation, it was not internationally acknowledged until long after his death that the underlying theory of "defensive enzymes" (Abwehrfermente) was entirely fraudulent (Deichmann & Müller-Hill 1998).

References

  • Deichmann, U. & Müller-Hill, B. (1998): The fraud of Abderhalden's enzymes. Nature 393:109-111. HTML abstract
  • Firkin, B. G. & Whitworth, J. A. (1987): Dictionary of Medical Eponyms. Parthenon Publishing. ISBN 1-85070-333-7
  • Van Slyke, Donald D.; Vinograd-Villchur, Mariam; and Losee, J.R. (1915): The Abderhalden Reaction. Journal of Biological Chemistry 23(1):377-406. PDF fulltext experimental evidence of the unreliability of the Abderhalden pregnancy test
  • Who Named It?


Cost Effectiveness of Abderhalden reaction

| group5 = Clinical Trials Involving Abderhalden reaction | list5 = Ongoing Trials on Abderhalden reaction at Clinical Trials.govTrial results on Abderhalden reactionClinical Trials on Abderhalden reaction at Google


| group6 = Guidelines / Policies / Government Resources (FDA/CDC) Regarding Abderhalden reaction | list6 = US National Guidelines Clearinghouse on Abderhalden reactionNICE Guidance on Abderhalden reactionNHS PRODIGY GuidanceFDA on Abderhalden reactionCDC on Abderhalden reaction


| group7 = Textbook Information on Abderhalden reaction | list7 = Books and Textbook Information on Abderhalden reaction


| group8 = Pharmacology Resources on Abderhalden reaction | list8 = AND (Dose)}} Dosing of Abderhalden reactionAND (drug interactions)}} Drug interactions with Abderhalden reactionAND (side effects)}} Side effects of Abderhalden reactionAND (Allergy)}} Allergic reactions to Abderhalden reactionAND (overdose)}} Overdose information on Abderhalden reactionAND (carcinogenicity)}} Carcinogenicity information on Abderhalden reactionAND (pregnancy)}} Abderhalden reaction in pregnancyAND (pharmacokinetics)}} Pharmacokinetics of Abderhalden reaction


| group9 = Genetics, Pharmacogenomics, and Proteinomics of Abderhalden reaction | list9 = AND (pharmacogenomics)}} Genetics of Abderhalden reactionAND (pharmacogenomics)}} Pharmacogenomics of Abderhalden reactionAND (proteomics)}} Proteomics of Abderhalden reaction


| group10 = Newstories on Abderhalden reaction | list10 = Abderhalden reaction in the newsBe alerted to news on Abderhalden reactionNews trends on Abderhalden reaction


| group11 = Commentary on Abderhalden reaction | list11 = Blogs on Abderhalden reaction

| group12 = Patient Resources on Abderhalden reaction | list12 = Patient resources on Abderhalden reactionDiscussion groups on Abderhalden reactionPatient Handouts on Abderhalden reactionDirections to Hospitals Treating Abderhalden reactionRisk calculators and risk factors for Abderhalden reaction


| group13 = Healthcare Provider Resources on Abderhalden reaction | list13 = Symptoms of Abderhalden reactionCauses & Risk Factors for Abderhalden reactionDiagnostic studies for Abderhalden reactionTreatment of Abderhalden reaction

| group14 = Continuing Medical Education (CME) Programs on Abderhalden reaction | list14 = CME Programs on Abderhalden reaction

| group15 = International Resources on Abderhalden reaction | list15 = Abderhalden reaction en EspanolAbderhalden reaction en Francais

| group16 = Business Resources on Abderhalden reaction | list16 = Abderhalden reaction in the MarketplacePatents on Abderhalden reaction

| group17 = Informatics Resources on Abderhalden reaction | list17 = List of terms related to Abderhalden reaction


}}



Linked-in.jpg