AP3S2: Difference between revisions

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Identifiers
Aliases
External IDs	GeneCards: [1]
Orthologs
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Latest revision as of 12:45, 9 January 2019

AP-3 complex subunit sigma-2 is a protein that in humans is encoded by the AP3S2 gene.^[1]^[2]

Interactions

AP3S2 has been shown to interact with AP3B1.^[3]

References

↑ Dell'Angelica EC, Ohno H, Ooi CE, Rabinovich E, Roche KW, Bonifacino JS (Apr 1997). "AP-3: an adaptor-like protein complex with ubiquitous expression". EMBO J. 16 (5): 917–28. doi:10.1093/emboj/16.5.917. PMC 1169692. PMID 9118953.
↑ "Entrez Gene: AP3S2 adaptor-related protein complex 3, sigma 2 subunit".
↑ Dell'Angelica, E C; Ooi C E; Bonifacino J S (Jun 1997). "Beta3A-adaptin, a subunit of the adaptor-like complex AP-3". J. Biol. Chem. UNITED STATES. 272 (24): 15078–84. doi:10.1074/jbc.272.24.15078. ISSN 0021-9258. PMID 9182526.

Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Dell'Angelica EC, Ooi CE, Bonifacino JS (1997). "Beta3A-adaptin, a subunit of the adaptor-like complex AP-3". J. Biol. Chem. 272 (24): 15078–84. doi:10.1074/jbc.272.24.15078. PMID 9182526.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Rous BA, Reaves BJ, Ihrke G, et al. (2002). "Role of adaptor complex AP-3 in targeting wild-type and mutated CD63 to lysosomes". Mol. Biol. Cell. 13 (3): 1071–82. doi:10.1091/mbc.01-08-0409. PMC 99620. PMID 11907283.
Falcón-Pérez JM, Starcevic M, Gautam R, Dell'Angelica EC (2002). "BLOC-1, a novel complex containing the pallidin and muted proteins involved in the biogenesis of melanosomes and platelet-dense granules". J. Biol. Chem. 277 (31): 28191–9. doi:10.1074/jbc.M204011200. PMID 12019270.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Nie Z, Boehm M, Boja ES, et al. (2003). "Specific regulation of the adaptor protein complex AP-3 by the Arf GAP AGAP1". Dev. Cell. 5 (3): 513–21. doi:10.1016/S1534-5807(03)00234-X. PMID 12967569.
Salazar G, Love R, Werner E, et al. (2004). "The zinc transporter ZnT3 interacts with AP-3 and it is preferentially targeted to a distinct synaptic vesicle subpopulation". Mol. Biol. Cell. 15 (2): 575–87. doi:10.1091/mbc.E03-06-0401. PMC 329249. PMID 14657250.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Lefrançois S, Janvier K, Boehm M, et al. (2004). "An ear-core interaction regulates the recruitment of the AP-3 complex to membranes". Dev. Cell. 7 (4): 619–25. doi:10.1016/j.devcel.2004.08.009. PMID 15469849.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514.

External links

AP3S2 human gene location in the UCSC Genome Browser.
AP3S2 human gene details in the UCSC Genome Browser.

This protein-related article is a stub. You can help Wikipedia by expanding it.

[pmid9118953-1] Dell'Angelica EC, Ohno H, Ooi CE, Rabinovich E, Roche KW, Bonifacino JS (Apr 1997). "AP-3: an adaptor-like protein complex with ubiquitous expression". EMBO J. 16 (5): 917–28. doi:10.1093/emboj/16.5.917. PMC 1169692. PMID 9118953.

[entrez-2] "Entrez Gene: AP3S2 adaptor-related protein complex 3, sigma 2 subunit".

[pmid9182526-3] Dell'Angelica, E C; Ooi C E; Bonifacino J S (Jun 1997). "Beta3A-adaptin, a subunit of the adaptor-like complex AP-3". J. Biol. Chem. UNITED STATES. 272 (24): 15078–84. doi:10.1074/jbc.272.24.15078. ISSN 0021-9258. PMID 9182526.

[1]

[2]

[3]

@@ Line 1: / Line 1: @@
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+{{Infobox_gene}}
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+'''AP-3 complex subunit sigma-2''' is a [[protein]] that in humans is encoded by the ''AP3S2'' [[gene]].<ref name="pmid9118953">{{cite journal |vauthors=Dell'Angelica EC, Ohno H, Ooi CE, Rabinovich E, Roche KW, Bonifacino JS | title = AP-3: an adaptor-like protein complex with ubiquitous expression | journal = EMBO J | volume = 16 | issue = 5 | pages = 917–28 |date=Apr 1997 | pmid = 9118953 | pmc = 1169692 | doi = 10.1093/emboj/16.5.917 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: AP3S2 adaptor-related protein complex 3, sigma 2 subunit| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10239| accessdate = }}</ref>
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- | image =
- | image_source =
- | PDB =
- | Name = Adaptor-related protein complex 3, sigma 2 subunit
- | HGNCid = 571
- | Symbol = AP3S2
- | AltSymbols =; AP3S3; FLJ35955; sigma3b
- | OMIM = 602416
- | ECnumber =
- | Homologene = 80198
- | MGIid = 1337060
- | Function =
- | Component = {{GNF_GO|id=GO:0005794 |text = Golgi apparatus}} {{GNF_GO|id=GO:0030662 |text = coated vesicle membrane}}
- | Process = {{GNF_GO|id=GO:0006810 |text = transport}} {{GNF_GO|id=GO:0006886 |text = intracellular protein transport}}
- | Orthologs = {{GNF_Ortholog_box
-    | Hs_EntrezGene = 10239
-    | Hs_Ensembl =
-    | Hs_RefseqProtein = NP_005820
-    | Hs_RefseqmRNA = NM_005829
-    | Hs_GenLoc_db =
-    | Hs_GenLoc_chr =
-    | Hs_GenLoc_start =
-    | Hs_GenLoc_end =
-    | Hs_Uniprot =
-    | Mm_EntrezGene = 11778
-    | Mm_Ensembl = ENSMUSG00000063801
-    | Mm_RefseqmRNA = NM_009682
-    | Mm_RefseqProtein = NP_033812
-    | Mm_GenLoc_db =
-    | Mm_GenLoc_chr = 7
-    | Mm_GenLoc_start = 79748838
-    | Mm_GenLoc_end = 79794114
-    | Mm_Uniprot = Q6PAL3
-  }}
-}}
-'''Adaptor-related protein complex 3, sigma 2 subunit''', also known as '''AP3S2''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: AP3S2 adaptor-related protein complex 3, sigma 2 subunit| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10239| accessdate = }}</ref>
 <!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
@@ Line 52: / Line 7: @@
 | summary_text =
 }}
+==Interactions==
+AP3S2 has been shown to [[Protein-protein interaction|interact]] with [[AP3B1]].<ref name=pmid9182526>{{cite journal |last=Dell'Angelica |first=E C |authorlink= |author2=Ooi C E |author3=Bonifacino J S  |date=Jun 1997 |title=Beta3A-adaptin, a subunit of the adaptor-like complex AP-3 |journal=J. Biol. Chem. |volume=272 |issue=24 |pages=15078–84 |publisher= |location = UNITED STATES| issn = 0021-9258| pmid = 9182526 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |doi=10.1074/jbc.272.24.15078 }}</ref>
 ==References==
-{{reflist|2}}
+{{reflist}}
 ==Further reading==
 {{refbegin | 2}}
 {{PBB_Further_reading
 | citations =
-*{{cite journal  | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171-4 |year= 1994 |pmid= 8125298 |doi=  }}
+*{{cite journal  |vauthors=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1–2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=10.1016/0378-1119(94)90802-8  }}
-*{{cite journal  | author=Dell'Angelica EC, Ohno H, Ooi CE, ''et al.'' |title=AP-3: an adaptor-like protein complex with ubiquitous expression. |journal=EMBO J. |volume=16 |issue= 5 |pages= 917-28 |year= 1997 |pmid= 9118953 |doi= 10.1093/emboj/16.5.917 }}
+*{{cite journal  |vauthors=Dell'Angelica EC, Ooi CE, Bonifacino JS |title=Beta3A-adaptin, a subunit of the adaptor-like complex AP-3 |journal=J. Biol. Chem. |volume=272 |issue= 24 |pages= 15078–84 |year= 1997 |pmid= 9182526 |doi=10.1074/jbc.272.24.15078  }}
-*{{cite journal  | author=Dell'Angelica EC, Ooi CE, Bonifacino JS |title=Beta3A-adaptin, a subunit of the adaptor-like complex AP-3. |journal=J. Biol. Chem. |volume=272 |issue= 24 |pages= 15078-84 |year= 1997 |pmid= 9182526 |doi=  }}
+*{{cite journal  |vauthors=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library |journal=Gene |volume=200 |issue= 1–2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=10.1016/S0378-1119(97)00411-3  |display-authors=etal}}
-*{{cite journal  | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, ''et al.'' |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149-56 |year= 1997 |pmid= 9373149 |doi=  }}
+*{{cite journal  |vauthors=Rous BA, Reaves BJ, Ihrke G |title=Role of adaptor complex AP-3 in targeting wild-type and mutated CD63 to lysosomes |journal=Mol. Biol. Cell |volume=13 |issue= 3 |pages= 1071–82 |year= 2002 |pmid= 11907283 |doi= 10.1091/mbc.01-08-0409  | pmc=99620 |display-authors=etal}}
-*{{cite journal  | author=Rous BA, Reaves BJ, Ihrke G, ''et al.'' |title=Role of adaptor complex AP-3 in targeting wild-type and mutated CD63 to lysosomes. |journal=Mol. Biol. Cell |volume=13 |issue= 3 |pages= 1071-82 |year= 2002 |pmid= 11907283 |doi= 10.1091/mbc.01-08-0409 }}
+*{{cite journal  |vauthors=Falcón-Pérez JM, Starcevic M, Gautam R, Dell'Angelica EC |title=BLOC-1, a novel complex containing the pallidin and muted proteins involved in the biogenesis of melanosomes and platelet-dense granules |journal=J. Biol. Chem. |volume=277 |issue= 31 |pages= 28191–9 |year= 2002 |pmid= 12019270 |doi= 10.1074/jbc.M204011200 }}
-*{{cite journal  | author=Falcón-Pérez JM, Starcevic M, Gautam R, Dell'Angelica EC |title=BLOC-1, a novel complex containing the pallidin and muted proteins involved in the biogenesis of melanosomes and platelet-dense granules. |journal=J. Biol. Chem. |volume=277 |issue= 31 |pages= 28191-9 |year= 2002 |pmid= 12019270 |doi= 10.1074/jbc.M204011200 }}
+*{{cite journal  |vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241 |display-authors=etal|bibcode=2002PNAS...9916899M }}
-*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
+*{{cite journal  |vauthors=Nie Z, Boehm M, Boja ES |title=Specific regulation of the adaptor protein complex AP-3 by the Arf GAP AGAP1 |journal=Dev. Cell |volume=5 |issue= 3 |pages= 513–21 |year= 2003 |pmid= 12967569 |doi=10.1016/S1534-5807(03)00234-X  |display-authors=etal}}
-*{{cite journal  | author=Nie Z, Boehm M, Boja ES, ''et al.'' |title=Specific regulation of the adaptor protein complex AP-3 by the Arf GAP AGAP1. |journal=Dev. Cell |volume=5 |issue= 3 |pages= 513-21 |year= 2003 |pmid= 12967569 |doi=  }}
+*{{cite journal  |vauthors=Salazar G, Love R, Werner E |title=The zinc transporter ZnT3 interacts with AP-3 and it is preferentially targeted to a distinct synaptic vesicle subpopulation |journal=Mol. Biol. Cell |volume=15 |issue= 2 |pages= 575–87 |year= 2004 |pmid= 14657250 |doi= 10.1091/mbc.E03-06-0401  | pmc=329249 |display-authors=etal}}
-*{{cite journal  | author=Salazar G, Love R, Werner E, ''et al.'' |title=The zinc transporter ZnT3 interacts with AP-3 and it is preferentially targeted to a distinct synaptic vesicle subpopulation. |journal=Mol. Biol. Cell |volume=15 |issue= 2 |pages= 575-87 |year= 2004 |pmid= 14657250 |doi= 10.1091/mbc.E03-06-0401 }}
+*{{cite journal  |vauthors=Ota T, Suzuki Y, Nishikawa T |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |display-authors=etal}}
-*{{cite journal  | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
+*{{cite journal  |vauthors=Lefrançois S, Janvier K, Boehm M |title=An ear-core interaction regulates the recruitment of the AP-3 complex to membranes |journal=Dev. Cell |volume=7 |issue= 4 |pages= 619–25 |year= 2004 |pmid= 15469849 |doi= 10.1016/j.devcel.2004.08.009 |display-authors=etal}}
-*{{cite journal  | author=Lefrançois S, Janvier K, Boehm M, ''et al.'' |title=An ear-core interaction regulates the recruitment of the AP-3 complex to membranes. |journal=Dev. Cell |volume=7 |issue= 4 |pages= 619-25 |year= 2004 |pmid= 15469849 |doi= 10.1016/j.devcel.2004.08.009 }}
+*{{cite journal  |vauthors=Gerhard DS, Wagner L, Feingold EA |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504  | pmc=528928 |display-authors=etal}}
-*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
+*{{cite journal  |vauthors=Rual JF, Venkatesan K, Hao T |title=Towards a proteome-scale map of the human protein-protein interaction network |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 |display-authors=etal|bibcode=2005Natur.437.1173R }}
-*{{cite journal  | author=Rual JF, Venkatesan K, Hao T, ''et al.'' |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173-8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }}
 }}
 {{refend}}
+==External links==
+* {{UCSC genome browser|AP3S2}}
+* {{UCSC gene details|AP3S2}}
+<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
+{{PBB_Controls
+| update_page = yes
+| require_manual_inspection = no
+| update_protein_box = yes
+| update_summary = yes
+| update_citations = yes
+}}
 {{protein-stub}}
-{{WikiDoc Sources}}

AP3S2: Difference between revisions

Latest revision as of 12:45, 9 January 2019

Contents

Interactions

References

Further reading

External links

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