AKAP1: Difference between revisions

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{{Infobox_gene}}
{{PBB_Controls
'''A kinase anchor protein 1, mitochondrial''' is an [[enzyme]] that in humans is encoded by the ''AKAP1'' [[gene]].<ref name="pmid8769136">{{cite journal |vauthors=Trendelenburg G, Hummel M, Riecken EO, Hanski C | title = Molecular characterization of AKAP149, a novel A kinase anchor protein with a KH domain | journal = Biochem Biophys Res Commun | volume = 225 | issue = 1 | pages = 313–9 |date=Sep 1996 | pmid = 8769136 | pmc =  | doi = 10.1006/bbrc.1996.1172 }}</ref><ref name="pmid7499250">{{cite journal |vauthors=Lin RY, Moss SB, Rubin CS | title = Characterization of S-AKAP84, a novel developmentally regulated A kinase anchor protein of male germ cells | journal = J Biol Chem | volume = 270 | issue = 46 | pages = 27804–11 |date=Jan 1996 | pmid = 7499250 | pmc = | doi =10.1074/jbc.270.46.27804  }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: AKAP1 A kinase (PRKA) anchor protein 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8165| accessdate = }}</ref>
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
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<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
== Function ==
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = A kinase (PRKA) anchor protein 1
| HGNCid = 367
| Symbol = AKAP1
| AltSymbols =; AKAP; AKAP121; AKAP149; AKAP84; D-AKAP1; MGC1807; PRKA1; SAKAP84
| OMIM = 602449
| ECnumber = 
| Homologene = 31165
| MGIid = 104729
| GeneAtlas_image1 = PBB_GE_AKAP1_201675_at_tn.png
| GeneAtlas_image2 = PBB_GE_AKAP1_201674_s_at_tn.png
| GeneAtlas_image3 = PBB_GE_AKAP1_210625_s_at_tn.png
| Function = {{GNF_GO|id=GO:0003723 |text = RNA binding}}
| Component = {{GNF_GO|id=GO:0005739 |text = mitochondrion}} {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}} {{GNF_GO|id=GO:0019867 |text = outer membrane}}
| Process =
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 8165
    | Hs_Ensembl = ENSG00000121057
    | Hs_RefseqProtein = NP_003479
    | Hs_RefseqmRNA = NM_003488
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 17
    | Hs_GenLoc_start = 52517620
    | Hs_GenLoc_end = 52553608
    | Hs_Uniprot = Q92667
    | Mm_EntrezGene = 11640
    | Mm_Ensembl = ENSMUSG00000018428
    | Mm_RefseqmRNA = NM_001042541
    | Mm_RefseqProtein = NP_001036006
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 11
    | Mm_GenLoc_start = 88646885
    | Mm_GenLoc_end = 88680674
    | Mm_Uniprot = Q5SX24
  }}
}}
'''A kinase (PRKA) anchor protein 1''', also known as '''AKAP1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: AKAP1 A kinase (PRKA) anchor protein 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8165| accessdate = }}</ref>


<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
The [[AKAP|A-kinase anchor protein]]s (AKAPs) are a group of structurally diverse proteins that have the common function of binding to the regulatory subunit of [[protein kinase A]] (PKA) and confining the [[holoenzyme]] to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein binds to type I and type II regulatory subunits of PKA and anchors them to the [[mitochondrion]]. This protein is speculated to be involved in the [[cyclic adenosine monophosphate|cAMP]]-dependent signal transduction pathway and in directing RNA to a specific cellular compartment.<ref name="entrez" />
{{PBB_Summary
 
| section_title =
== Interactions ==
| summary_text = The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein binds to type I and type II regulatory subunits of PKA and anchors them to the mitochondrion. This protein is speculated to be involved in the cAMP-dependent signal transduction pathway and in directing RNA to a specific cellular compartment.<ref name="entrez">{{cite web | title = Entrez Gene: AKAP1 A kinase (PRKA) anchor protein 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8165| accessdate = }}</ref>
 
}}
AKAP1 has been shown to [[Protein-protein interaction|interact]] with:
{{div col|colwidth=20em}}
* [[C3orf15]],<ref name = pmid12223483/>
* [[MYCBP]],<ref name = pmid12223483>{{cite journal | date = Nov 2002 |vauthors=Yukitake H, Furusawa M, Taira T, Iguchi-Ariga SM, Ariga H | title = AAT-1, a novel testis-specific AMY-1-binding protein, forms a quaternary complex with AMY-1, A-kinase anchor protein 84, and a regulatory subunit of cAMP-dependent protein kinase and is phosphorylated by its kinase | journal = J. Biol. Chem. | volume = 277 | issue = 47 | pages = 45480–92 | pmid = 12223483 | doi = 10.1074/jbc.M206201200}}</ref><ref name = pmid11483602>{{cite journal | date = Sep 2001 |vauthors=Furusawa M, Ohnishi T, Taira T, Iguchi-Ariga SM, Ariga H | title = AMY-1, a c-Myc-binding protein, is localized in the mitochondria of sperm by association with S-AKAP84, an anchor protein of cAMP-dependent protein kinase | journal = J. Biol. Chem. | volume = 276 | issue = 39 | pages = 36647–51 | pmid = 11483602 | doi = 10.1074/jbc.M103885200}}</ref>
* [[PRKAR1A]],<ref name = pmid12634056>{{cite journal | date = Mar 2003 |vauthors=Carlson CR, Ruppelt A, Taskén K | title = A kinase anchoring protein (AKAP) interaction and dimerization of the RIalpha and RIbeta regulatory subunits of protein kinase a in vivo by the yeast two hybrid system | journal = J. Mol. Biol. | volume = 327 | issue = 3 | pages = 609–18 | pmid = 12634056 | doi = 10.1016/S0022-2836(03)00093-7}}</ref><ref name = pmid10764601>{{cite journal | date = April 2000 | vauthors = Herberg FW, Maleszka A, Eide T, Vossebein L, Tasken K | title = Analysis of A-kinase anchoring protein (AKAP) interaction with protein kinase A (PKA) regulatory subunits: PKA isoform specificity in AKAP binding | journal = J. Mol. Biol. | volume = 298 | issue = 2 | pages = 329–39 | pmid = 10764601 | doi = 10.1006/jmbi.2000.3662}}</ref>
* [[PRKAR1B]],<ref name = pmid12634056/> and
* [[PRKAR2A]].<ref name = pmid10764601/><ref name = pmid10413680>{{cite journal | date = Aug 1999 |vauthors=Kapiloff MS, Schillace RV, Westphal AM, Scott JD | title = mAKAP: an A-kinase anchoring protein targeted to the nuclear membrane of differentiated myocytes | journal = J. Cell Sci. | volume = 112 | issue = 16| pages = 2725–36 | pmid = 10413680 | doi = }}</ref>  
{{Div col end}}


==References==
==References==
{{reflist|2}}
{{Reflist}}
 
==External links==
* {{UCSC gene info|AKAP1}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{Refbegin | 2}}
{{PBB_Further_reading
*{{cite journal  |vauthors=Lester LB, Scott JD |title=Anchoring and scaffold proteins for kinases and phosphatases |journal=Recent Prog. Horm. Res. |volume=52 |issue=  |pages= 409–29; discussion 429–30 |year= 1997 |pmid= 9238861 |doi=  }}
| citations =
*{{cite journal  |vauthors=Michel JJ, Scott JD |title=AKAP mediated signal transduction |journal=Annu. Rev. Pharmacol. Toxicol. |volume=42 |issue=  |pages= 235–57 |year= 2002 |pmid= 11807172 |doi= 10.1146/annurev.pharmtox.42.083101.135801 }}
*{{cite journal  | author=Lester LB, Scott JD |title=Anchoring and scaffold proteins for kinases and phosphatases. |journal=Recent Prog. Horm. Res. |volume=52 |issue=  |pages= 409-29; discussion 429-30 |year= 1997 |pmid= 9238861 |doi=  }}
*{{cite journal  |vauthors=Huang LJ, Durick K, Weiner JA |title=Identification of a novel protein kinase A anchoring protein that binds both type I and type II regulatory subunits |journal=J. Biol. Chem. |volume=272 |issue= 12 |pages= 8057–64 |year= 1997 |pmid= 9065479 |doi=10.1074/jbc.272.12.8057  |display-authors=etal}}
*{{cite journal  | author=Michel JJ, Scott JD |title=AKAP mediated signal transduction. |journal=Annu. Rev. Pharmacol. Toxicol. |volume=42 |issue=  |pages= 235-57 |year= 2002 |pmid= 11807172 |doi= 10.1146/annurev.pharmtox.42.083101.135801 }}
*{{cite journal  |vauthors=Huang LJ, Wang L, Ma Y |title=NH2-Terminal Targeting Motifs Direct Dual Specificity A-Kinase–anchoring Protein 1 (D-AKAP1) to Either Mitochondria or Endoplasmic Reticulum |journal=J. Cell Biol. |volume=145 |issue= 5 |pages= 951–9 |year= 1999 |pmid= 10352013 |doi=10.1083/jcb.145.5.951  | pmc=2133123  |display-authors=etal}}
*{{cite journal  | author=Lin RY, Moss SB, Rubin CS |title=Characterization of S-AKAP84, a novel developmentally regulated A kinase anchor protein of male germ cells. |journal=J. Biol. Chem. |volume=270 |issue= 46 |pages= 27804-11 |year= 1996 |pmid= 7499250 |doi= }}
*{{cite journal  |vauthors=Herberg FW, Maleszka A, Eide T |title=Analysis of A-kinase anchoring protein (AKAP) interaction with protein kinase A (PKA) regulatory subunits: PKA isoform specificity in AKAP binding |journal=J. Mol. Biol. |volume=298 |issue= 2 |pages= 329–39 |year= 2000 |pmid= 10764601 |doi= 10.1006/jmbi.2000.3662 |display-authors=etal}}
*{{cite journal  | author=Trendelenburg G, Hummel M, Riecken EO, Hanski C |title=Molecular characterization of AKAP149, a novel A kinase anchor protein with a KH domain. |journal=Biochem. Biophys. Res. Commun. |volume=225 |issue= 1 |pages= 313-9 |year= 1996 |pmid= 8769136 |doi= 10.1006/bbrc.1996.1172 }}
*{{cite journal  |vauthors=Steen RL, Martins SB, Taskén K, Collas P |title=Recruitment of Protein Phosphatase 1 to the Nuclear Envelope by a-Kinase Anchoring Protein Akap149 Is a Prerequisite for Nuclear Lamina Assembly |journal=J. Cell Biol. |volume=150 |issue= 6 |pages= 1251–62 |year= 2000 |pmid= 10995432 |doi=10.1083/jcb.150.6.1251  | pmc=2150688 }}
*{{cite journal  | author=Huang LJ, Durick K, Weiner JA, ''et al.'' |title=Identification of a novel protein kinase A anchoring protein that binds both type I and type II regulatory subunits. |journal=J. Biol. Chem. |volume=272 |issue= 12 |pages= 8057-64 |year= 1997 |pmid= 9065479 |doi= }}
*{{cite journal  |vauthors=Furusawa M, Ohnishi T, Taira T |title=AMY-1, a c-Myc-binding protein, is localized in the mitochondria of sperm by association with S-AKAP84, an anchor protein of cAMP-dependent protein kinase |journal=J. Biol. Chem. |volume=276 |issue= 39 |pages= 36647–51 |year= 2001 |pmid= 11483602 |doi= 10.1074/jbc.M103885200 |display-authors=etal}}
*{{cite journal  | author=Huang LJ, Wang L, Ma Y, ''et al.'' |title=NH2-Terminal targeting motifs direct dual specificity A-kinase-anchoring protein 1 (D-AKAP1) to either mitochondria or endoplasmic reticulum. |journal=J. Cell Biol. |volume=145 |issue= 5 |pages= 951-9 |year= 1999 |pmid= 10352013 |doi=  }}
*{{cite journal  |vauthors=Razani B, Lisanti MP |title=Two distinct caveolin-1 domains mediate the functional interaction of caveolin-1 with protein kinase A |journal=Am. J. Physiol., Cell Physiol. |volume=281 |issue= 4 |pages= C1241–50 |year= 2001 |pmid= 11546661 |doi=  }}
*{{cite journal  | author=Herberg FW, Maleszka A, Eide T, ''et al.'' |title=Analysis of A-kinase anchoring protein (AKAP) interaction with protein kinase A (PKA) regulatory subunits: PKA isoform specificity in AKAP binding. |journal=J. Mol. Biol. |volume=298 |issue= 2 |pages= 329-39 |year= 2000 |pmid= 10764601 |doi= 10.1006/jmbi.2000.3662 }}
*{{cite journal  |vauthors=Yukitake H, Furusawa M, Taira T |title=AAT-1, a novel testis-specific AMY-1-binding protein, forms a quaternary complex with AMY-1, A-kinase anchor protein 84, and a regulatory subunit of cAMP-dependent protein kinase and is phosphorylated by its kinase |journal=J. Biol. Chem. |volume=277 |issue= 47 |pages= 45480–92 |year= 2003 |pmid= 12223483 |doi= 10.1074/jbc.M206201200 |display-authors=etal}}
*{{cite journal  | author=Steen RL, Martins SB, Taskén K, Collas P |title=Recruitment of protein phosphatase 1 to the nuclear envelope by A-kinase anchoring protein AKAP149 is a prerequisite for nuclear lamina assembly. |journal=J. Cell Biol. |volume=150 |issue= 6 |pages= 1251-62 |year= 2000 |pmid= 10995432 |doi=  }}
*{{cite journal  |vauthors=Furusawa M, Taira T, Iguchi-Ariga SM, Ariga H |title=AMY-1 interacts with S-AKAP84 and AKAP95 in the cytoplasm and the nucleus, respectively, and inhibits cAMP-dependent protein kinase activity by preventing binding of its catalytic subunit to A-kinase-anchoring protein (AKAP) complex |journal=J. Biol. Chem. |volume=277 |issue= 52 |pages= 50885–92 |year= 2003 |pmid= 12414807 |doi= 10.1074/jbc.M206387200 }}
*{{cite journal  | author=Furusawa M, Ohnishi T, Taira T, ''et al.'' |title=AMY-1, a c-Myc-binding protein, is localized in the mitochondria of sperm by association with S-AKAP84, an anchor protein of cAMP-dependent protein kinase. |journal=J. Biol. Chem. |volume=276 |issue= 39 |pages= 36647-51 |year= 2001 |pmid= 11483602 |doi= 10.1074/jbc.M103885200 }}
*{{cite journal  |vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241 |display-authors=etal}}
*{{cite journal  | author=Razani B, Lisanti MP |title=Two distinct caveolin-1 domains mediate the functional interaction of caveolin-1 with protein kinase A. |journal=Am. J. Physiol., Cell Physiol. |volume=281 |issue= 4 |pages= C1241-50 |year= 2001 |pmid= 11546661 |doi= }}
*{{cite journal  |vauthors=Carlson CR, Ruppelt A, Taskén K |title=A kinase anchoring protein (AKAP) interaction and dimerization of the RIalpha and RIbeta regulatory subunits of protein kinase a in vivo by the yeast two hybrid system |journal=J. Mol. Biol. |volume=327 |issue= 3 |pages= 609–18 |year= 2003 |pmid= 12634056 |doi=10.1016/S0022-2836(03)00093-7  }}
*{{cite journal  | author=Yukitake H, Furusawa M, Taira T, ''et al.'' |title=AAT-1, a novel testis-specific AMY-1-binding protein, forms a quaternary complex with AMY-1, A-kinase anchor protein 84, and a regulatory subunit of cAMP-dependent protein kinase and is phosphorylated by its kinase. |journal=J. Biol. Chem. |volume=277 |issue= 47 |pages= 45480-92 |year= 2003 |pmid= 12223483 |doi= 10.1074/jbc.M206201200 }}
*{{cite journal  |vauthors=Steen RL, Beullens M, Landsverk HB |title=AKAP149 is a novel PP1 specifier required to maintain nuclear envelope integrity in G1 phase |journal=J. Cell Sci. |volume=116 |issue= Pt 11 |pages= 2237–46 |year= 2004 |pmid= 12697839 |doi= 10.1242/jcs.00432 |display-authors=etal}}
*{{cite journal  | author=Furusawa M, Taira T, Iguchi-Ariga SM, Ariga H |title=AMY-1 interacts with S-AKAP84 and AKAP95 in the cytoplasm and the nucleus, respectively, and inhibits cAMP-dependent protein kinase activity by preventing binding of its catalytic subunit to A-kinase-anchoring protein (AKAP) complex. |journal=J. Biol. Chem. |volume=277 |issue= 52 |pages= 50885-92 |year= 2003 |pmid= 12414807 |doi= 10.1074/jbc.M206387200 }}
*{{cite journal  |vauthors=Hillman RT, Green RE, Brenner SE |title=An unappreciated role for RNA surveillance |journal=Genome Biol. |volume=5 |issue= 2 |pages= R8 |year= 2005 |pmid= 14759258 |doi= 10.1186/gb-2004-5-2-r8  | pmc=395752 }}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  |vauthors=Cardone L, Carlucci A, Affaitati A |title=Mitochondrial AKAP121 Binds and Targets Protein Tyrosine Phosphatase D1, a Novel Positive Regulator of src Signaling |journal=Mol. Cell. Biol. |volume=24 |issue= 11 |pages= 4613–26 |year= 2004 |pmid= 15143158 |doi= 10.1128/MCB.24.11.4613-4626.2004  | pmc=416429 |display-authors=etal}}
*{{cite journal  | author=Carlson CR, Ruppelt A, Taskén K |title=A kinase anchoring protein (AKAP) interaction and dimerization of the RIalpha and RIbeta regulatory subunits of protein kinase a in vivo by the yeast two hybrid system. |journal=J. Mol. Biol. |volume=327 |issue= 3 |pages= 609-18 |year= 2003 |pmid= 12634056 |doi= }}
*{{cite journal  |vauthors=Beausoleil SA, Jedrychowski M, Schwartz D |title=Large-scale characterization of HeLa cell nuclear phosphoproteins |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 33 |pages= 12130–5 |year= 2004 |pmid= 15302935 |doi= 10.1073/pnas.0404720101  | pmc=514446 |display-authors=etal}}
*{{cite journal  | author=Steen RL, Beullens M, Landsverk HB, ''et al.'' |title=AKAP149 is a novel PP1 specifier required to maintain nuclear envelope integrity in G1 phase. |journal=J. Cell. Sci. |volume=116 |issue= Pt 11 |pages= 2237-46 |year= 2004 |pmid= 12697839 |doi= 10.1242/jcs.00432 }}
{{Refend}}
*{{cite journal  | author=Hillman RT, Green RE, Brenner SE |title=An unappreciated role for RNA surveillance. |journal=Genome Biol. |volume=5 |issue= 2 |pages= R8 |year= 2005 |pmid= 14759258 |doi= 10.1186/gb-2004-5-2-r8 }}
 
*{{cite journal  | author=Cardone L, Carlucci A, Affaitati A, ''et al.'' |title=Mitochondrial AKAP121 binds and targets protein tyrosine phosphatase D1, a novel positive regulator of src signaling. |journal=Mol. Cell. Biol. |volume=24 |issue= 11 |pages= 4613-26 |year= 2004 |pmid= 15143158 |doi= 10.1128/MCB.24.11.4613-4626.2004 }}
[[Category:A-kinase-anchoring proteins]]
*{{cite journal  | author=Beausoleil SA, Jedrychowski M, Schwartz D, ''et al.'' |title=Large-scale characterization of HeLa cell nuclear phosphoproteins. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 33 |pages= 12130-5 |year= 2004 |pmid= 15302935 |doi= 10.1073/pnas.0404720101 }}
 
}}
{{refend}}


{{protein-stub}}
{{Gene-17-stub}}
{{WikiDoc Sources}}

Latest revision as of 19:16, 8 November 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

A kinase anchor protein 1, mitochondrial is an enzyme that in humans is encoded by the AKAP1 gene.[1][2][3]

Function

The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins that have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein binds to type I and type II regulatory subunits of PKA and anchors them to the mitochondrion. This protein is speculated to be involved in the cAMP-dependent signal transduction pathway and in directing RNA to a specific cellular compartment.[3]

Interactions

AKAP1 has been shown to interact with:

References

  1. ↑ Trendelenburg G, Hummel M, Riecken EO, Hanski C (Sep 1996). "Molecular characterization of AKAP149, a novel A kinase anchor protein with a KH domain". Biochem Biophys Res Commun. 225 (1): 313–9. doi:10.1006/bbrc.1996.1172. PMID 8769136.
  2. ↑ Lin RY, Moss SB, Rubin CS (Jan 1996). "Characterization of S-AKAP84, a novel developmentally regulated A kinase anchor protein of male germ cells". J Biol Chem. 270 (46): 27804–11. doi:10.1074/jbc.270.46.27804. PMID 7499250.
  3. ↑ 3.0 3.1 "Entrez Gene: AKAP1 A kinase (PRKA) anchor protein 1".
  4. ↑ 4.0 4.1 Yukitake H, Furusawa M, Taira T, Iguchi-Ariga SM, Ariga H (Nov 2002). "AAT-1, a novel testis-specific AMY-1-binding protein, forms a quaternary complex with AMY-1, A-kinase anchor protein 84, and a regulatory subunit of cAMP-dependent protein kinase and is phosphorylated by its kinase". J. Biol. Chem. 277 (47): 45480–92. doi:10.1074/jbc.M206201200. PMID 12223483.
  5. ↑ Furusawa M, Ohnishi T, Taira T, Iguchi-Ariga SM, Ariga H (Sep 2001). "AMY-1, a c-Myc-binding protein, is localized in the mitochondria of sperm by association with S-AKAP84, an anchor protein of cAMP-dependent protein kinase". J. Biol. Chem. 276 (39): 36647–51. doi:10.1074/jbc.M103885200. PMID 11483602.
  6. ↑ 6.0 6.1 Carlson CR, Ruppelt A, Taskén K (Mar 2003). "A kinase anchoring protein (AKAP) interaction and dimerization of the RIalpha and RIbeta regulatory subunits of protein kinase a in vivo by the yeast two hybrid system". J. Mol. Biol. 327 (3): 609–18. doi:10.1016/S0022-2836(03)00093-7. PMID 12634056.
  7. ↑ 7.0 7.1 Herberg FW, Maleszka A, Eide T, Vossebein L, Tasken K (April 2000). "Analysis of A-kinase anchoring protein (AKAP) interaction with protein kinase A (PKA) regulatory subunits: PKA isoform specificity in AKAP binding". J. Mol. Biol. 298 (2): 329–39. doi:10.1006/jmbi.2000.3662. PMID 10764601.
  8. ↑ Kapiloff MS, Schillace RV, Westphal AM, Scott JD (Aug 1999). "mAKAP: an A-kinase anchoring protein targeted to the nuclear membrane of differentiated myocytes". J. Cell Sci. 112 (16): 2725–36. PMID 10413680.

External links

Further reading


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