Sandbox/guillermo

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Helicobacter pylori medical treatment

▸ Click on the following categories to expand treatment regimens.[1][2]

First line

  ▸  Triple therapy

  ▸  Quadruple therapy

Second line

  ▸  Triple therapy

  ▸  Sequential therapy

Rescue therapy

  ▸  Basilar Skull Fracture

Triple therapy
PPI standard dose
PLUS
Clarithromycin 500 mg q12h.
PLUS
Amoxicillin 1,0000 mg q12h
Quadruple therapy
Bismuth subsalicylate 525 mg orally q6h
PLUS
Metronidazol 250 mg orally q6—8h
PLUS
Tetracycline 500 mg orally q6—8h
PLUS
Ranitidine 150 mg orally q12h
OR
PPI standard dose
Triple therapy
PPI standard dose
PLUS
Clarithromycin 500 mg q12h
PLUS
Metronidazole 500 mg q12h
Sequential therapy
First 5 days
Bismuth subsalicylate 525 mg orally q6h
PLUS
Metronidazol 250 mg orally q6—8h
Next 5 days
Tetracycline 500 mg orally q6—8h
PLUS
Ranitidine 150 mg orally q12h
OR
PPI standard dose
CSF Shunt Infection
Preferred Regimen
Vancomycin 15 mg/kg IV q8—12h (trough 15—20 μg/mL)
PLUS
Cefepime 2 g IV q8h
OR
Ceftazidime 2 g IV q8h
OR
Meropenem 2 g IV q8h
Alternative Regimen
Vancomycin 15 mg/kg IV q8—12h (trough 15—20 μg/mL)
PLUS
Aztreonam 2 g IV q6—8h
OR
Ciprofloxacin 400 mg IV q8—12h
Penetrating Trauma
Preferred Regimen
Vancomycin 15 mg/kg IV q8—12h (trough 15—20 μg/mL)
PLUS
Cefepime 2 g IV q8h
OR
Ceftazidime 2 g IV q8h
OR
Meropenem 2 g IV q8h
Alternative Regimen
Vancomycin 15 mg/kg IV q8—12h (trough 15—20 μg/mL)
PLUS
Aztreonam 2 g IV q6—8h
OR
Ciprofloxacin 400 mg IV q8—12h
Basilar Skull Fracture
Preferred Regimen
Vancomycin 15 mg/kg IV q8—12h (trough 15—20 μg/mL)
PLUS
Cefotaxime 2 g IV q4—6h
OR
Ceftriaxone 2 g IV q12h
Alternative Regimen
Vancomycin 15 mg/kg IV q8—12h (trough 15—20 μg/mL)
PLUS
Aztreonam 2 g IV q6—8h
OR
Ciprofloxacin 400 mg IV q8—12h

References

  1. van de Beek, D.; Drake, JM.; Tunkel, AR. (2010). "Nosocomial bacterial meningitis". N Engl J Med. 362 (2): 146–54. doi:10.1056/NEJMra0804573. PMID 20071704. Unknown parameter |month= ignored (help)
  2. van de Beek, D.; Brouwer, MC.; Thwaites, GE.; Tunkel, AR. (2012). "Advances in treatment of bacterial meningitis". Lancet. 380 (9854): 1693–702. doi:10.1016/S0140-6736(12)61186-6. PMID 23141618. Unknown parameter |month= ignored (help)