Sandbox vidit5

Revision as of 21:22, 18 December 2013 by Vidit Bhargava (talk | contribs)
Jump to navigation Jump to search
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Characterize the symptoms:
❑ Increased cough
❑ Increased Dyspnea
❑ Increased sputum production
❑ Wheezing
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Examine the patient:
Pulse oximetry
Arterial blood gas
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Consider alternative dagnosis:
Pulmonary embolism
Heart failure
Asthma exacerbation
Bronchiectasis
❑ Broncholitis obliterans
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Supplement Oxygen: (Urgent)
Maintain SaO2 ≥ 88-92%
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Need for ICU admission?

❑ Hemodynamic instability AND/OR
❑ Changes in mental status (confusion, lethargy, coma) AND/OR
❑ Severe dyspnea that responds inadequately to initial emergency therapy AND/OR
❑ Worsening hypoxemia (PaO2 <40 mm Hg) and/or respiratory acidosis (pH <7.25)
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
No
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Yes
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Indications for Hospitalization:

❑ Marked increase in intensity of symptoms (eg, sudden development of resting dyspnea)
❑ Presence of serious comorbidities (eg, heart failure or newly occurring arrhythmias)
❑ Failure of an exacerbation to respond to initial medical management
❑ Onset of new physical signs (eg, cyanosis, peripheral edema)
❑ Severe underlying COPD (GOLD 3—4 categories)
❑ Frequent exacerbations (≥2 events per year)
❑ Insufficient home support
❑ Older age (>65 years)
 
 
 
 
 
Assessment of Exacerbation:

❑ Cardinal symptoms (↑ dyspnea, ↑ sputum volume, and ↑ sputum purulence)
❑ ECG (identify coexisting cardiac problems)
❑ Chest radiograph (exclude alternative diagnoses)
❑ Whole-blood count (identify polycythemia, anemia, or leukocytosis)
❑ Electrolytes and glucose (identify electrolyte disturbances or hyperglycemia)
 
 
 
 
 
 
 
 
 
 
❑ Admit patient to ICU
❑ Classify as Life-threatening COPD exacerbation
❑ Assess patients need for mechanical ventilation
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Indications for Noninvasive Mechanical Ventilation

❑ Respiratory acidosis (arterial pH < 7.35 or PaCO2 >45 mm Hg)
❑ Severe dyspnea with signs of respiratory muscle fatigue
❑ Increased work of breathing
 
 
 
Indications for Invasive Mechanical Ventilation

❑ Diminished consciousness, psychomotor agitation inadequately controlled by sedation
❑ Severe hemodynamic instability without response to fluids and vasoactive drugs
❑ Respiratory pauses with loss of consciousness or gasping for air
❑ Life-threatening hypoxemia in patients unable to tolerate NIV
❑ Persistent inability to remove respiratory secretions
❑ Heart rate <50/min with loss of alertness
❑ Severe ventricular arrhythmias
❑ Respiratory or cardiac arrest
❑ Failure of initial trial of NIV
❑ Massive aspiration
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Mild Exacerbation (⊕ 1 cardinal symptom)
❑ Consider outpatient management
❑ Require change of inhaled treatment by the patient
 
 
Moderate Exacerbation (⊕ 2 cardinal symptoms)
❑ Consider outpatient management
❑ Require a short course of antibiotics and/or oral corticosteroids
 
 
Severe Exacerbation (⊕ 3 cardinal symptoms)

❑ Consider inpatient management
❑ Assess symptoms, ABG, and CXR
❑ Monitor fluid balance and nutrition
❑ Identify and treat associated conditions
❑ Consider subcutaneous heparin or LMWH
❑ Controlled oxygen therapy (consider NIV if indicated)
❑ Antibiotics (if ↑ sputum purulence or ⊕ bacterial infection)
❑ Corticosteroids
❑ Bronchodilators
▸ Increase doses/frequency of short-acting bronchodilators
▸ Combine short-acting β2-agonists and anticholinergics
▸ Use spacers or air-driven nebulizers