TFG (gene)

TRK-fused gene
Identifiers
Symbols	TFG ; FLJ36137; TF6; TRKT3
External IDs	Template:OMIM5 Template:MGI HomoloGene: 4426
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
File:PBB GE TFG 217839 at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

TRK-fused gene, also known as TFG, is a human gene.

Further reading

• Sasaoka T, Kobayashi M (2000). "The functional significance of Shc in insulin signaling as a substrate of the insulin receptor". Endocr. J. 47 (4): 373–81. PMID 11075717.
• Greco A, Mariani C, Miranda C; et al. (1995). "The DNA rearrangement that generates the TRK-T3 oncogene involves a novel gene on chromosome 3 whose product has a potential coiled-coil domain". Mol. Cell. Biol. 15 (11): 6118–27. PMID 7565764.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gotoh N, Toyoda M, Shibuya M (1997). "Tyrosine phosphorylation sites at amino acids 239 and 240 of Shc are involved in epidermal growth factor-induced mitogenic signaling that is distinct from Ras/mitogen-activated protein kinase activation". Mol. Cell. Biol. 17 (4): 1824–31. PMID 9121430.CS1 maint: Multiple names: authors list (link)
• Mencinger M, Panagopoulos I, Andreasson P; et al. (1997). "Characterization and chromosomal mapping of the human TFG gene involved in thyroid carcinoma". Genomics. 41 (3): 327–31. doi:10.1006/geno.1997.4625. PMID 9169129.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Soltoff SP, Avraham H, Avraham S, Cantley LC (1998). "Activation of P2Y2 receptors by UTP and ATP stimulates mitogen-activated kinase activity through a pathway that involves related adhesion focal tyrosine kinase and protein kinase C.". J. Biol. Chem. 273 (5): 2653–60. PMID 9446569.CS1 maint: Multiple names: authors list (link)
• Walk SF, March ME, Ravichandran KS (1998). "Roles of Lck, Syk and ZAP-70 tyrosine kinases in TCR-mediated phosphorylation of the adapter protein Shc". Eur. J. Immunol. 28 (8): 2265–75. PMID 9710204.CS1 maint: Multiple names: authors list (link)
• Wary KK, Mariotti A, Zurzolo C, Giancotti FG (1998). "A requirement for caveolin-1 and associated kinase Fyn in integrin signaling and anchorage-dependent cell growth". Cell. 94 (5): 625–34. PMID 9741627.CS1 maint: Multiple names: authors list (link)
• Marchetto S, Fournier E, Beslu N; et al. (1999). "SHC and SHIP phosphorylation and interaction in response to activation of the FLT3 receptor". Leukemia. 13 (9): 1374–82. PMID 10482988.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Hernández L, Pinyol M, Hernández S; et al. (1999). "TRK-fused gene (TFG) is a new partner of ALK in anaplastic large cell lymphoma producing two structurally different TFG-ALK translocations". Blood. 94 (9): 3265–8. PMID 10556217.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Nakajima K, Yamauchi K, Shigematsu S; et al. (2000). "Selective attenuation of metabolic branch of insulin receptor down-signaling by high glucose in a hepatoma cell line, HepG2 cells". J. Biol. Chem. 275 (27): 20880–6. doi:10.1074/jbc.M905410199. PMID 10764799.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Slack BE (2000). "The m3 muscarinic acetylcholine receptor is coupled to mitogen-activated protein kinase via protein kinase C and epidermal growth factor receptor kinase". Biochem. J. 348 Pt 2: 381–7. PMID 10816433.
• Schaak S, Cussac D, Cayla C; et al. (2000). "Alpha(2) adrenoceptors regulate proliferation of human intestinal epithelial cells". Gut. 47 (2): 242–50. PMID 10896916.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Imokawa G, Kobayasi T, Miyagishi M (2000). "Intracellular signaling mechanisms leading to synergistic effects of endothelin-1 and stem cell factor on proliferation of cultured human melanocytes. Cross-talk via trans-activation of the tyrosine kinase c-kit receptor". J. Biol. Chem. 275 (43): 33321–8. doi:10.1074/jbc.M004346200. PMID 10921922.CS1 maint: Multiple names: authors list (link)
• Suzuki H, Fukunishi Y, Kagawa I; et al. (2001). "Protein-protein interaction panel using mouse full-length cDNAs". Genome Res. 11 (10): 1758–65. doi:10.1101/gr.180101. PMID 11591653.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Hernández L, Beà S, Bellosillo B; et al. (2002). "Diversity of genomic breakpoints in TFG-ALK translocations in anaplastic large cell lymphomas: identification of a new TFG-ALK(XL) chimeric gene with transforming activity". Am. J. Pathol. 160 (4): 1487–94. PMID 11943732.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Roccato E, Miranda C, Ranzi V; et al. (2002). "Biological activity of the thyroid TRK-T3 oncogene requires signalling through Shc". Br. J. Cancer. 87 (6): 645–53. doi:10.1038/sj.bjc.6600544. PMID 12237775.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Matsuda A, Suzuki Y, Honda G; et al. (2003). "Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways". Oncogene. 22 (21): 3307–18. doi:10.1038/sj.onc.1206406. PMID 12761501.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)