SLIT2

Slit homolog 2 (Drosophila)
Identifiers
Symbols	SLIT2 ; FLJ14420; SLIL3; Slit-2
External IDs	Template:OMIM5 Template:MGI HomoloGene: 3516
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
File:PBB GE SLIT2 209897 s at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Slit homolog 2 (Drosophila), also known as SLIT2, is a human gene.

Further reading

• Wong K, Park HT, Wu JY, Rao Y (2003). "Slit proteins: molecular guidance cues for cells ranging from neurons to leukocytes". Curr. Opin. Genet. Dev. 12 (5): 583–91. PMID 12200164.CS1 maint: Multiple names: authors list (link)
• Itoh A, Miyabayashi T, Ohno M, Sakano S (1999). "Cloning and expressions of three mammalian homologues of Drosophila slit suggest possible roles for Slit in the formation and maintenance of the nervous system". Brain Res. Mol. Brain Res. 62 (2): 175–86. PMID 9813312.CS1 maint: Multiple names: authors list (link)
• Wang KH, Brose K, Arnott D; et al. (1999). "Biochemical purification of a mammalian slit protein as a positive regulator of sensory axon elongation and branching". Cell. 96 (6): 771–84. PMID 10102266.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Brose K, Bland KS, Wang KH; et al. (1999). "Slit proteins bind Robo receptors and have an evolutionarily conserved role in repulsive axon guidance". Cell. 96 (6): 795–806. PMID 10102268.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Li HS, Chen JH, Wu W; et al. (1999). "Vertebrate slit, a secreted ligand for the transmembrane protein roundabout, is a repellent for olfactory bulb axons". Cell. 96 (6): 807–18. PMID 10102269.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Nguyen Ba-Charvet KT, Brose K, Marillat V; et al. (1999). "Slit2-Mediated chemorepulsion and collapse of developing forebrain axons". Neuron. 22 (3): 463–73. PMID 10197527.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Holmes GP, Negus K, Burridge L; et al. (1999). "Distinct but overlapping expression patterns of two vertebrate slit homologs implies functional roles in CNS development and organogenesis". Mech. Dev. 79 (1–2): 57–72. PMID 10349621.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Liang Y, Annan RS, Carr SA; et al. (1999). "Mammalian homologues of the Drosophila slit protein are ligands of the heparan sulfate proteoglycan glypican-1 in brain". J. Biol. Chem. 274 (25): 17885–92. PMID 10364234.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Wu W, Wong K, Chen J; et al. (1999). "Directional guidance of neuronal migration in the olfactory system by the protein Slit". Nature. 400 (6742): 331–6. doi:10.1038/22477. PMID 10432110.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Georgas K, Burridge L, Smith K; et al. (2000). "Assignment of the human slit homologue SLIT2 to human chromosome band 4p15.2". Cytogenet. Cell Genet. 86 (3–4): 246–7. PMID 10575218.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Niclou SP, Jia L, Raper JA (2000). "Slit2 is a repellent for retinal ganglion cell axons". J. Neurosci. 20 (13): 4962–74. PMID 10864954.CS1 maint: Multiple names: authors list (link)
• Zou Y, Stoeckli E, Chen H, Tessier-Lavigne M (2000). "Squeezing axons out of the gray matter: a role for slit and semaphorin proteins from midline and ventral spinal cord". Cell. 102 (3): 363–75. PMID 10975526.CS1 maint: Multiple names: authors list (link)
• Chen JH, Wen L, Dupuis S; et al. (2001). "The N-terminal leucine-rich regions in Slit are sufficient to repel olfactory bulb axons and subventricular zone neurons". J. Neurosci. 21 (5): 1548–56. PMID 11222645.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Stein E, Tessier-Lavigne M (2001). "Hierarchical organization of guidance receptors: silencing of netrin attraction by slit through a Robo/DCC receptor complex". Science. 291 (5510): 1928–38. doi:10.1126/science.1058445. PMID 11239147.
• Wu JY, Feng L, Park HT; et al. (2001). "The neuronal repellent Slit inhibits leukocyte chemotaxis induced by chemotactic factors". Nature. 410 (6831): 948–52. doi:10.1038/35073616. PMID 11309622.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ronca F, Andersen JS, Paech V, Margolis RU (2001). "Characterization of Slit protein interactions with glypican-1". J. Biol. Chem. 276 (31): 29141–7. doi:10.1074/jbc.M100240200. PMID 11375980.CS1 maint: Multiple names: authors list (link)
• Nguyen Ba-Charvet KT, Brose K, Ma L; et al. (2001). "Diversity and specificity of actions of Slit2 proteolytic fragments in axon guidance". J. Neurosci. 21 (12): 4281–9. PMID 11404413.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Little M, Rumballe B, Georgas K; et al. (2003). "Conserved modularity and potential for alternate splicing in mouse and human Slit genes". Int. J. Dev. Biol. 46 (4): 385–91. PMID 12141424.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Dallol A, Da Silva NF, Viacava P; et al. (2002). "SLIT2, a human homologue of the Drosophila Slit2 gene, has tumor suppressor activity and is frequently inactivated in lung and breast cancers". Cancer Res. 62 (20): 5874–80. PMID 12384551.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)