RTN3

Reticulon 3
Identifiers
Symbols	RTN3 ; HAP; ASYIP; NSPL2; NSPLII; RTN3-A1
External IDs	Template:OMIM5 Template:MGI HomoloGene: 24934
Gene ontology Cellular component Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
File:PBB GE RTN3 219549 s at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Reticulon 3, also known as RTN3, is a human gene.

The reticulons are a group of highly conserved genes with preferential expression in neuroendocrine tissues (see, e.g., RTN1; MIM 600865).[supplied by OMIM]

Further reading

• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. PMID 8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K; et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. PMID 9373149.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Moreira EF, Jaworski CJ, Rodriguez IR (1999). "Cloning of a novel member of the reticulon gene family (RTN3): gene structure and chromosomal localization to 11q13". Genomics. 58 (1): 73–81. doi:10.1006/geno.1999.5807. PMID 10331947.CS1 maint: Multiple names: authors list (link)
• Qu X, Qi Y, Qi B (2002). "Generation of multiple mRNA transcripts from the novel human apoptosis-inducing gene hap by alternative polyadenylation utilization and the translational activation function of 3' untranslated region". Arch. Biochem. Biophys. 400 (2): 233–44. doi:10.1016/S0003-9861(02)00016-4. PMID 12054434.CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Qi B, Qi Y, Watari A; et al. (2003). "Pro-apoptotic ASY/Nogo-B protein associates with ASYIP". J. Cell. Physiol. 196 (2): 312–8. doi:10.1002/jcp.10297. PMID 12811824.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Oertle T, Klinger M, Stuermer CA, Schwab ME (2003). "A reticular rhapsody: phylogenic evolution and nomenclature of the RTN/Nogo gene family". FASEB J. 17 (10): 1238–47. doi:10.1096/fj.02-1166hyp. PMID 12832288.CS1 maint: Multiple names: authors list (link)
• Di Sano F, Fazi B, Citro G; et al. (2003). "Glucosylceramide synthase and its functional interaction with RTN-1C regulate chemotherapeutic-induced apoptosis in neuroepithelioma cells". Cancer Res. 63 (14): 3860–5. PMID 12873973.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Huang X, Yang H, Zhou Y; et al. (2004). "Overexpression of human reticulon 3 (hRTN3) in astrocytoma". Clin. Neuropathol. 23 (1): 1–7. PMID 14986927.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Hu Y, Fang X, Dunham SM; et al. (2004). "90-kDa ribosomal S6 kinase is a direct target for the nuclear fibroblast growth factor receptor 1 (FGFR1): role in FGFR1 signaling". J. Biol. Chem. 279 (28): 29325–35. doi:10.1074/jbc.M311144200. PMID 15117958.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• He W, Lu Y, Qahwash I; et al. (2004). "Reticulon family members modulate BACE1 activity and amyloid-beta peptide generation". Nat. Med. 10 (9): 959–65. doi:10.1038/nm1088. PMID 15286784.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Di Scala F, Dupuis L, Gaiddon C; et al. (2005). "Tissue specificity and regulation of the N-terminal diversity of reticulon 3". Biochem. J. 385 (Pt 1): 125–34. doi:10.1042/BJ20040458. PMID 15350194.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gan M, Qi Y, Wan Q; et al. (2005). "Mammalian apoptosis-inducing protein, HAP, induces bacterial cell death". Mol. Biol. Rep. 31 (3): 159–64. PMID 15560370.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Kuang E, Wan Q, Li X; et al. (2005). "ER Ca2+ depletion triggers apoptotic signals for endoplasmic reticulum (ER) overload response induced by overexpressed reticulon 3 (RTN3/HAP)". J. Cell. Physiol. 204 (2): 549–59. doi:10.1002/jcp.20340. PMID 15799019.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Cai Y, Saiyin H, Lin Q; et al. (2005). "Identification of a new RTN3 transcript, RTN3-A1, and its distribution in adult mouse brain". Brain Res. Mol. Brain Res. 138 (2): 236–43. doi:10.1016/j.molbrainres.2005.04.020. PMID 15946766.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Wakana Y, Koyama S, Nakajima K; et al. (2005). "Reticulon 3 is involved in membrane trafficking between the endoplasmic reticulum and Golgi". Biochem. Biophys. Res. Commun. 334 (4): 1198–205. doi:10.1016/j.bbrc.2005.07.012. PMID 16054885.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Rual JF, Venkatesan K, Hao T; et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Otsuki T, Ota T, Nishikawa T; et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries". DNA Res. 12 (2): 117–26. doi:10.1093/dnares/12.2.117. PMID 16303743.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)