PSTPIP1

Proline-serine-threonine phosphatase interacting protein 1
File:PBB Protein PSTPIP1 image.jpg PDB rendering based on 2dil.
Available structures PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB List of PDB id codes 2dil​
Identifiers
Symbols	PSTPIP1 ; CD2BP1; CD2BP1L; CD2BP1S; H-PIP; PAPAS; PSTPIP
External IDs	Template:OMIM5 Template:MGI HomoloGene: 37867
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO
RNA expression pattern
File:PBB GE PSTPIP1 211178 s at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Proline-serine-threonine phosphatase interacting protein 1, also known as PSTPIP1, is a human gene.

Further reading

• Spencer S, Dowbenko D, Cheng J; et al. (1997). "PSTPIP: a tyrosine phosphorylated cleavage furrow-associated protein that is a substrate for a PEST tyrosine phosphatase". J. Cell Biol. 138 (4): 845–60. PMID 9265651.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Dowbenko D, Spencer S, Quan C, Lasky LA (1998). "Identification of a novel polyproline recognition site in the cytoskeletal associated protein, proline serine threonine phosphatase interacting protein". J. Biol. Chem. 273 (2): 989–96. PMID 9422760.CS1 maint: Multiple names: authors list (link)
• Wu Y, Spencer SD, Lasky LA (1998). "Tyrosine phosphorylation regulates the SH3-mediated binding of the Wiskott-Aldrich syndrome protein to PSTPIP, a cytoskeletal-associated protein". J. Biol. Chem. 273 (10): 5765–70. PMID 9488710.CS1 maint: Multiple names: authors list (link)
• Wu Y, Dowbenko D, Lasky LA (1998). "PSTPIP 2, a second tyrosine phosphorylated, cytoskeletal-associated protein that binds a PEST-type protein-tyrosine phosphatase". J. Biol. Chem. 273 (46): 30487–96. PMID 9804817.CS1 maint: Multiple names: authors list (link)
• Li J, Nishizawa K, An W; et al. (1999). "A cdc15-like adaptor protein (CD2BP1) interacts with the CD2 cytoplasmic domain and regulates CD2-triggered adhesion". EMBO J. 17 (24): 7320–36. doi:10.1093/emboj/17.24.7320. PMID 9857189.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Cong F, Spencer S, Côté JF; et al. (2001). "Cytoskeletal protein PSTPIP1 directs the PEST-type protein tyrosine phosphatase to the c-Abl kinase to mediate Abl dephosphorylation". Mol. Cell. 6 (6): 1413–23. PMID 11163214.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Oda A, Ochs HD, Lasky LA; et al. (2001). "CrkL is an adapter for Wiskott-Aldrich syndrome protein and Syk". Blood. 97 (9): 2633–9. PMID 11313252.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Côté JF, Chung PL, Théberge JF; et al. (2002). "PSTPIP is a substrate of PTP-PEST and serves as a scaffold guiding PTP-PEST toward a specific dephosphorylation of WASP". J. Biol. Chem. 277 (4): 2973–86. doi:10.1074/jbc.M106428200. PMID 11711533.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Wise CA, Gillum JD, Seidman CE; et al. (2003). "Mutations in CD2BP1 disrupt binding to PTP PEST and are responsible for PAPA syndrome, an autoinflammatory disorder". Hum. Mol. Genet. 11 (8): 961–9. PMID 11971877.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Badour K, Zhang J, Shi F; et al. (2003). "The Wiskott-Aldrich syndrome protein acts downstream of CD2 and the CD2AP and PSTPIP1 adaptors to promote formation of the immunological synapse". Immunity. 18 (1): 141–54. PMID 12530983.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Shoham NG, Centola M, Mansfield E; et al. (2004). "Pyrin binds the PSTPIP1/CD2BP1 protein, defining familial Mediterranean fever and PAPA syndrome as disorders in the same pathway". Proc. Natl. Acad. Sci. U.S.A. 100 (23): 13501–6. doi:10.1073/pnas.2135380100. PMID 14595024.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Rual JF, Venkatesan K, Hao T; et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Baum W, Kirkin V, Fernández SB; et al. (2006). "Binding of the intracellular Fas ligand (FasL) domain to the adaptor protein PSTPIP results in a cytoplasmic localization of FasL". J. Biol. Chem. 280 (48): 40012–24. doi:10.1074/jbc.M502222200. PMID 16204241.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Yang H, Reinherz EL (2006). "CD2BP1 modulates CD2-dependent T cell activation via linkage to protein tyrosine phosphatase (PTP)-PEST". J. Immunol. 176 (10): 5898–907. PMID 16670297.
• Ewing RM, Chu P, Elisma F; et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3: 89. doi:10.1038/msb4100134. PMID 17353931.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)