Atrial septal defect Eisenmenger's syndrome

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Atrial Septal Defect Microchapters

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Overview

Anatomy

Classification

Ostium Secundum Atrial Septal Defect
Ostium Primum Atrial Septal Defect
Sinus Venosus Atrial Septal Defect
Coronary Sinus
Patent Foramen Ovale
Common or Single Atrium

Pathophysiology

Epidemiology and Demographics

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Diagnosis

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Special Scenarios

Pregnancy
Diving and Decompression Sickness
Paradoxical Emboli
Pulmonary Hypertension
Eisenmenger's Syndrome
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Case #1

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editors-In-Chief: Priyamvada Singh, M.B.B.S. [2]; Cafer Zorkun, M.D., Ph.D. [3]; Assistant Editor-In-Chief: Kristin Feeney, B.S. [4]

Overview

Eisenmenger's syndrome outcome is generally poor irrespective of the modalities of treatments used i.e. surgical or medical

Eisenmenger's syndrome and atrial septal defect

If eisenmenger's syndrome has occurred, there is significant risk of mortality regardless of the method of closure of the atrial septal defect. In individuals who have developed eisenmenger's syndrome, the pressure in the right ventricle has elevated high enough to reverse the shunt in the atria. If the atrial septal defect is then closed, the afterload that the right ventricle has to act against has suddenly increased that may lead to acute right ventricular failure (since it may not be able to pump the blood against the pulmonary hypertension). Some of the complications that might occur with eisenmenger's syndrome are thrombosis, bleeding, consideration for organ transplant (lung or heart-lung), and increased risk of maternal mortality during pregnancy.

References

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