Sandbox:Trusha

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Trusha Tank, M.D.[2]

Diseases	Clinical manifestations						Para-clinical findings						Gold standard	Additional findings
	Symptoms				Physical exam
							Lab Findings		Radiology			Histopathology
	Cough/Sputum	Hemoptysis	Weight loss	Other symptoms	Percussion	Auscultation	CBC	Sputum analysis	Nodule	Nodule content	Other findings
Pulmonary Nodule(benign)	N/A	-	-	Asymptomatic	Hyporesonance Dull percussion	Normal Present pleural friction rub Present egophony Crackling or bubbling noises Present whispered pectoriloquy Decreased/absent breath sounds	Normal	Normal	Single Round, oval <5 mm nodule Ground glass	Calcification: Central dense nidus Diffuse solid Laminated Popcorn Fat in nodule	well-defined smooth border Growth rate over 18 months Cavity wall thickness of 1 mm	N/A	N/A
Pulmonary Nodule (malignant)	Chronic cough Sputum +/-	++	++	Dyspnea Hemoptysis Non resolving pneumonia Wheezing Chest pain Abdominal pain Cachexia Fatigue Loss of appetite Dysphonia Dysphagia	Hyporesonance Dull percussion	Normal Present pleural friction rub Present egophony Crackling or bubbling noises Present whispered pectoriloquy Decreased/absent breath sounds	Normal	Sputum cytology: Tumor cells	Multiple small Single > 2 cm of size Location: Upper lobe especially on the right Metastatic pulmonary nodules in lower lobes.	Calcification: Amorphous Punctate Reticular Stippled or eccentric	Spiculated border Rapid growth rate (Doubling time 1-18 months) Cavity wall thickness over 15 mm	central necrosis Cavity lined by viable cancer cells without necrosis	Biopsy and histopathological analysis
Infection
Diseases	Cough/Sputum	Cough/Sputum	Weight loss	Other symptoms	Percussion	Auscultation	CBC	Sputum analysis	Chest X-ray	CT scan	Other imaging	Histopathology	Gold standard	Additional findings
Abscess
Septic emboli
Fungi
Parasites
Mycobacterial infections
Chronic inflammatory conditions
Diseases	Cough/Sputum	Cough/Sputum	Weight loss	Other symptoms	Percussion	Auscultation	CBC	Sputum analysis	Chest X-ray	CT scan	Other imaging	Histopathology	Gold standard	Additional findings
Pulmonary AVMs
Pneumoconioses