Respiratory failure mechanical ventilation

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Overview

Mechanical ventilation

Mechanical ventilation aims to correct abnormalities in oxygenation of the blood and tissues, reduce the respiratory effort and prevent dynamic hyperinflation.

Indications

  • Life threatening respiratory failure:[1][2][3]
    • Severe respiratory failure with failure of non-invasive ventilation (NIV) in addition to rapid, shallow breathing, cardiopulmonary arrest, and severe hemodynamic compromise.
  • Failure of noninvasive ventilation:
    • Indications of failed NIV include:
      • A lack of improvement in arterial carbon dioxide tension (PaCO2) and pH within 1.5 - 2 hours
      • Encephalopathy
      • Agitation
      • Unclearable secretions
      • Intolerable mask interface
      • Decreased oxygen saturation
      • Hemodynamic instability
  • Arterial blood gas abnormalities
    • Incorrectable hypoxemia despite oxygen supplementation
    • Severe respiratory acidosis unresponsive to therapy and/or NIV

Endotracheal intubation

  • Endotracheal intubation acts as the connection between the ventilator and the patient.
  • Intubation can be performed endotracheally or through a tracheostomy.
  • The tube must be placed correctly, and this is confirmed through:
    • Chest x-ray
    • Chest auscultation
    • Carbon dioxide detector
  • Proper cuff pressure must be maintained and not exceed 25mmHg
  • The airways should be suctioned to ensure patency of the airway:
    • Suctioning may occur through an open or closed circuit suction catheter.
    • Routine suctioning is not recommended as this may lead to complications such as:
      • Desaturation
      • Arrhythmias
      • Bronchospasm
      • Cough
      • Entry of secretions into the lower respiratory tract
  • The endotracheal tube insertion depth varies by gender and is measured from the lower incisors:
    • In males: 23cm
    • In females: 21cm
  • The tube is affixed in place using tape to prevent accidental extubation or further downward movement toward the main bronchus.

Principles of Mechanical Ventilation

  • Mechanical ventilation is basically used to:
    • Increase PaO2
    • Lower PaCO2
    • Relieve respiratory effort

Types of Mechanical Ventilation

Ventilator Modes

Positive-End Expiratory Pressure

Inspiratory Flow

Ventilator Induced Lung Injury

References

  1. Davidson AC, Banham S, Elliott M, Kennedy D, Gelder C, Glossop A, Church AC, Creagh-Brown B, Dodd JW, Felton T, Foëx B, Mansfield L, McDonnell L, Parker R, Patterson CM, Sovani M, Thomas L (April 2016). "BTS/ICS guideline for the ventilatory management of acute hypercapnic respiratory failure in adults". Thorax. 71 Suppl 2: ii1–35. doi:10.1136/thoraxjnl-2015-208209. PMID 26976648.
  2. Confalonieri M, Garuti G, Cattaruzza MS, Osborn JF, Antonelli M, Conti G, Kodric M, Resta O, Marchese S, Gregoretti C, Rossi A (February 2005). "A chart of failure risk for noninvasive ventilation in patients with COPD exacerbation". Eur. Respir. J. 25 (2): 348–55. doi:10.1183/09031936.05.00085304. PMID 15684302.
  3. Phua J, Kong K, Lee KH, Shen L, Lim TK (April 2005). "Noninvasive ventilation in hypercapnic acute respiratory failure due to chronic obstructive pulmonary disease vs. other conditions: effectiveness and predictors of failure". Intensive Care Med. 31 (4): 533–9. doi:10.1007/s00134-005-2582-8. PMID 15742175.

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