Pseudohypoparathyroidism classification

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mazia Fatima, MBBS [2]

Overview

Pseudohypoparathyroidism(PTH) is classified based on the measurement of serum and urinary cAMP and phosphate excretion levels after the injection of biologically active parathyroid hormone into pseudohypoparathyroidism type I and pseudohypoparathyroidism type II.

Classification

  • Pseudohypoparathyroidism is classified based on the measurement of serum and urinary cAMP and phosphate excretion levels after the injection of biologically active parathyroid hormone into following types:[1]
    • Pseudohypoparathyroidism type I
    • Pseudohypoparathyroidism type II
  • Pseudohypoparathyroidism type 1 is further classified into following subtype:[1]
    • Pseudohypoparathyroidism type 1a
    • Pseudohypoparathyroidism type 1b
    • Pseudohypoparathyroidism type 1c.
    • Pseudopseudohypoparathyroidism
  • Other forms of parathyroid hormone resistance include :
    • Blomstrand Syndrome
    • Acrodysostosis type 1 
    • Acrodysostosis type 2 

References

  1. 1.0 1.1 Marx SJ (2000). "Hyperparathyroid and hypoparathyroid disorders". N. Engl. J. Med. 343 (25): 1863–75. doi:10.1056/NEJM200012213432508. PMID 11117980.


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