Differentiating systemic lupus erythematosus from other diseases
Systemic lupus erythematosus Microchapters |
Differentiating Systemic lupus erythematosus from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mahshid Mir, M.D. [2]
Overview
- Systemic lupus erythematosus (SLE) must be differentiated from other diseases that cause arthritis, positive autoimmune serology, and constitutional symptoms, such as rheumatoid arthritis(RA), mixed connective tissue disease (MCTD), Systemic sclerosis (SSc), Dermatomyositis (DM), polymyositis(PM), and other autoimmune diseases.
Differentiating systemic lupus erythematosus from other diseases
Systemic lupus erythematosus (SLE) must be differentiated from other diseases that cause arthritis, positive autoimmune serology, and constitutional symptoms, such as rheumatoid arthritis(RA), mixed connective tissue disease (MCTD), Systemic sclerosis (SSc), Dermatomyositis (DM), polymyositis(PM), and other autoimmune diseases.
Overlapping Features | Distinguishing/specific features | |||
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Rheumatoid arthritis (RA) |
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Rhupus |
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Mixed connective tissue disease (MCTD) |
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Undifferentiated connective tissue disease (UCTD) |
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Systemic sclerosis (SSc) |
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Sjögren’s syndrome |
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Vasculitis |
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Behçet’s syndrome |
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Dermatomyositis (DM) and polymyositis (PM) |
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Adult Still’s disease (ASD) |
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Kikuchi’s disease |
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Serum sickness |
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Fibromyalgia |
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Infections | Viruses |
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Human immunodeficiency virus (HIV) | ||||
Hepatitis B virus (HBV) | ||||
Hepatitis C virus (HCV) | ||||
Cytomegalovirus (CMV) | ||||
Epstein-Barr virus (EBV) | ||||
Bacterias | Salmonella | |||
Mycobacterium tuberculosis | ||||
Multiple sclerosis (MS) |
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Malignancies |
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Thrombotic thrombocytopenic purpura (TTP) |
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