Sandbox ID Gastrointestinal and Intraabdominal
Gastrointestinal anthrax
- Gastrointestinal anthrax
- Preferred regimen: Ciprofloxacin 400 mg intravenously every 8 h OR doxycycline 100 mg intravenously every 12 h combined with second agent: clindamycin 600 mg intravenously every 8 h or penicillin G 4 MU every 4–6 h OR meropenem 1 gm intravenously every 6–8 h or rifampin 300 mg every 12 h.
Infectious diarrhea
- Infectious diarrhea
Immunocompetent
- Shigella species:
- Preferred regimen:
- Adult dose: TMP-SMZ, 160 and 800 mg, respectively b.i.d. for 3 days (if susceptible ) OR fluoroquinolone (e.g., 300 mg ofloxacin, 400 mg norfloxacin, OR 500 mg ciprofloxacin b.i.d. for 3 days)
- Pediatric dose:TMP-SMZ, 5 and 25 mg/kg, respectively b.i.d. for 3 days
- Preferred regimen:
- Adult dose: Nalidixic acid 1 g/d X 5 d OR ceftriaxone; azithromycin
- Pediatric dose: Nalidixic acid, 55 mg/kg/d
- Campylobacter species
- Preferred regimen:
- Erythromycin, 500 mg b.i.d. X 5 d
- Escherichia coli species
- Enterotoxigenic
- Preferred regimen:
- TMP-SMZ, 160 and 800 mg, respectively, b.i.d. for 3 days (if susceptible), OR fluoroquinolone (e.g., 300 mg ofloxacin, 400 mg norfloxacin, or 500 mg ciprofloxacin b.i.d. for 3 days)
- Enteropathogenic
- Preferred regimen:
- TMP-SMZ, 160 and 800 mg, respectively, b.i.d.,X 3 d (if susceptible), OR fluoroquinolone (e.g., 300 mg ofloxacin, 400 mg norfloxacin, or 500 mg ciprofloxacin b.i.d. for 3 days)
- Enteroinvasive
- Preferred regimen:
- TMP-SMZ, 160 and 800 mg, respectively, b.i.d.,X 3 d (if susceptible), OR fluoroquinolone (e.g., 300 mg ofloxacin, 400 mg norfloxacin, or 500 mg ciprofloxacin b.i.d. for 3 days)
- Enterohemorrhagic
- Preferred regimen:
- Avoid antimotility drugs (E-II) [136]; role of antibiotics unclear, and administration should be avoided.
- Aeromonas/Plesiomonas
- Preferred regimen:
- TMP-SMZ, 160 and 800 mg, respectively, b.i.d. for 3 days (if susceptible), fluoroquinolone (e.g., 300 mg ofloxacin, 400 mg norfloxacin, or 500 mg ciprofloxacin b.i.d. for 3 days)
- Yersinia species
- Preferred regimen:
- Antibiotics are not usually required deferoxamine therapy should be withheld; for severe infections or associated bacteremia treat as for immunocompromised hosts.
Peptic ulcer disease
- Peptic ulcer disease
Esophagitis
- Esophagitis