Sandbox ID Gastrointestinal and Intraabdominal

Gastrointestinal anthrax

Further information: Anthrax medical therapy and therapeutic approach

• Gastrointestinal anthrax

• Preferred regimen: Ciprofloxacin 400 mg intravenously every 8 h OR doxycycline 100 mg intravenously every 12 h combined with second agent: clindamycin 600 mg intravenously every 8 h or penicillin G 4 MU every 4–6 h OR meropenem 1 gm intravenously every 6–8 h or rifampin 300 mg every 12 h.

---

Infectious diarrhea

Further information: Infectious diarrhea § Treatment, and therapeutic approach

• Infectious diarrhea

Immunocompetent

• Shigella species:

• Preferred regimen:

• Adult dose: TMP-SMZ, 160 and 800 mg, respectively b.i.d. for 3 days (if susceptible ) OR fluoroquinolone (e.g., 300 mg ofloxacin, 400 mg norfloxacin, OR 500 mg ciprofloxacin b.i.d. for 3 days)
• Pediatric dose:TMP-SMZ, 5 and 25 mg/kg, respectively b.i.d. for 3 days

• Preferred regimen:

• Adult dose: Nalidixic acid 1 g/d X 5 d OR ceftriaxone; azithromycin

• Pediatric dose: Nalidixic acid, 55 mg/kg/d

• Campylobacter species

• Preferred regimen:

• Erythromycin, 500 mg b.i.d. X 5 d

• Escherichia coli species

• Enterotoxigenic

• Preferred regimen:

• TMP-SMZ, 160 and 800 mg, respectively, b.i.d. for 3 days (if susceptible), OR fluoroquinolone (e.g., 300 mg ofloxacin, 400 mg norfloxacin, or 500 mg ciprofloxacin b.i.d. for 3 days)

• Enteropathogenic

• Preferred regimen:

• TMP-SMZ, 160 and 800 mg, respectively, b.i.d.,X 3 d (if susceptible), OR fluoroquinolone (e.g., 300 mg ofloxacin, 400 mg norfloxacin, or 500 mg ciprofloxacin b.i.d. for 3 days)

• Enteroinvasive

• Preferred regimen:

• TMP-SMZ, 160 and 800 mg, respectively, b.i.d.,X 3 d (if susceptible), OR fluoroquinolone (e.g., 300 mg ofloxacin, 400 mg norfloxacin, or 500 mg ciprofloxacin b.i.d. for 3 days)

• Enterohemorrhagic

• Preferred regimen:

• Avoid antimotility drugs (E-II) [136]; role of antibiotics unclear, and administration should be avoided.

Aeromonas/Plesiomonas

• Preferred regimen:

• TMP-SMZ, 160 and 800 mg, respectively, b.i.d. 3 3 d (if susceptible), fluoroquinoloneb (e.g., 300 mg ofloxacin, 400 mg norfloxacin, or 500 mg ciprofloxacin b.i.d. for 3 days)

---

Peptic ulcer disease

Further information: Peptic ulcer medical therapy and therapeutic approach

• Peptic ulcer disease

• Preferred regimen: DrugName Dosage_Duration OR DrugName Dosage_Duration
• Alternative regimen: DrugName Dosage_Duration

---

Esophagitis

Further information: Esophagitis medical therapy and therapeutic approach

• Esophagitis

• Preferred regimen: DrugName Dosage_Duration OR DrugName Dosage_Duration
• Alternative regimen: DrugName Dosage_Duration