Ramucirumab

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Ramucirumab
Black Box Warning
Adult Indications & Dosage
Pediatric Indications & Dosage
Contraindications
Warnings & Precautions
Adverse Reactions
Drug Interactions
Use in Specific Populations
Administration & Monitoring
Overdosage
Pharmacology
Clinical Studies
How Supplied
Images
Patient Counseling Information
Precautions with Alcohol
Brand Names
Look-Alike Names

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Alberto Plate [2]

Disclaimer

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Black Box Warning

TITLE
See full prescribing information for complete Boxed Warning.
Condition Name: (Content)

Overview

Ramucirumab is a monoclonal antibody that is FDA approved for the treatment of advanced or metastatic, gastric or gastro-esophageal junction adenocarcinoma with disease progression on or after prior fluoropyrimidine- or platinum-containing chemotherapy and metastatic non-small cell lung cancer (NSCLC) with disease progression on or after platinum-based chemotherapy. There is a Black Box Warning for this drug as shown here. Common adverse reactions include hypertension and diarrhea.

Adult Indications and Dosage

FDA-Labeled Indications and Dosage (Adult)

There is limited information regarding Ramucirumab FDA-Labeled Indications and Dosage (Adult) in the drug label.

Off-Label Use and Dosage (Adult)

Guideline-Supported Use

There is limited information regarding Off-Label Guideline-Supported Use of Ramucirumab in adult patients.

Non–Guideline-Supported Use

There is limited information regarding Off-Label Non–Guideline-Supported Use of Ramucirumab in adult patients.

Pediatric Indications and Dosage

FDA-Labeled Indications and Dosage (Pediatric)

There is limited information regarding Ramucirumab FDA-Labeled Indications and Dosage (Pediatric) in the drug label.

Off-Label Use and Dosage (Pediatric)

Guideline-Supported Use

There is limited information regarding Off-Label Guideline-Supported Use of Ramucirumab in pediatric patients.

Non–Guideline-Supported Use

There is limited information regarding Off-Label Non–Guideline-Supported Use of Ramucirumab in pediatric patients.

Contraindications

There is limited information regarding Ramucirumab Contraindications in the drug label.

Warnings

TITLE
See full prescribing information for complete Boxed Warning.
Condition Name: (Content)

There is limited information regarding Ramucirumab Warnings' in the drug label.

Adverse Reactions

Clinical Trials Experience

There is limited information regarding Ramucirumab Clinical Trials Experience in the drug label.

Postmarketing Experience

There is limited information regarding Ramucirumab Postmarketing Experience in the drug label.

Drug Interactions

There is limited information regarding Ramucirumab Drug Interactions in the drug label.

Use in Specific Populations

Pregnancy

Pregnancy Category (FDA): There is no FDA guidance on usage of Ramucirumab in women who are pregnant.
Pregnancy Category (AUS): There is no Australian Drug Evaluation Committee (ADEC) guidance on usage of Ramucirumab in women who are pregnant.

Labor and Delivery

There is no FDA guidance on use of Ramucirumab during labor and delivery.

Nursing Mothers

There is no FDA guidance on the use of Ramucirumab in women who are nursing.

Pediatric Use

There is no FDA guidance on the use of Ramucirumab in pediatric settings.

Geriatic Use

There is no FDA guidance on the use of Ramucirumab in geriatric settings.

Gender

There is no FDA guidance on the use of Ramucirumab with respect to specific gender populations.

Race

There is no FDA guidance on the use of Ramucirumab with respect to specific racial populations.

Renal Impairment

There is no FDA guidance on the use of Ramucirumab in patients with renal impairment.

Hepatic Impairment

There is no FDA guidance on the use of Ramucirumab in patients with hepatic impairment.

Females of Reproductive Potential and Males

There is no FDA guidance on the use of Ramucirumab in women of reproductive potentials and males.

Immunocompromised Patients

There is no FDA guidance one the use of Ramucirumab in patients who are immunocompromised.

Administration and Monitoring

Administration

There is limited information regarding Ramucirumab Administration in the drug label.

Monitoring

There is limited information regarding Ramucirumab Monitoring in the drug label.

IV Compatibility

There is limited information regarding the compatibility of Ramucirumab and IV administrations.

Overdosage

There is limited information regarding Ramucirumab overdosage. If you suspect drug poisoning or overdose, please contact the National Poison Help hotline (1-800-222-1222) immediately.

Pharmacology

There is limited information regarding Ramucirumab Pharmacology in the drug label.

Mechanism of Action

There is limited information regarding Ramucirumab Mechanism of Action in the drug label.

Structure

There is limited information regarding Ramucirumab Structure in the drug label.

Pharmacodynamics

There is limited information regarding Ramucirumab Pharmacodynamics in the drug label.

Pharmacokinetics

There is limited information regarding Ramucirumab Pharmacokinetics in the drug label.

Nonclinical Toxicology

There is limited information regarding Ramucirumab Nonclinical Toxicology in the drug label.

Clinical Studies

There is limited information regarding Ramucirumab Clinical Studies in the drug label.

How Supplied

There is limited information regarding Ramucirumab How Supplied in the drug label.

Storage

There is limited information regarding Ramucirumab Storage in the drug label.

Images

Drug Images

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Package and Label Display Panel

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Patient Counseling Information

There is limited information regarding Ramucirumab Patient Counseling Information in the drug label.

Precautions with Alcohol

Alcohol-Ramucirumab interaction has not been established. Talk to your doctor about the effects of taking alcohol with this medication.

Brand Names

There is limited information regarding Ramucirumab Brand Names in the drug label.

Look-Alike Drug Names

There is limited information regarding Ramucirumab Look-Alike Drug Names in the drug label.

Drug Shortage Status

Price

References

The contents of this FDA label are provided by the National Library of Medicine.