Enterovirus 68 overview

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Alejandro Lemor, M.D. [2]; João André Alves Silva, M.D. [3]

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Overview

Enterovirus 68 (EV68) is a member of the Enterovirus genus of the Picornaviridae family. It is a non-enveloped, positive-sense, single-stranded RNA virus. It is detected more frequently among pediatric patients in the United States and other countries. While enteroviruses can cause a wide range of symptoms ranging from mild febrile illness to fatal meningitis and encephalitis, EV68 is mostly associated with acute respiratory symptoms. In 2014, EV68 was isolated from 2 children with a polio-like flaccid paralysis; however, the virus could not be isolated among 3 other kids with a similar presentation.

Historical Perspective

Pathophysiology

Causes

Differentiating Enterovirus 68 from other Diseases

Epidemiology and Demographics

Risk Factors

Natural History, Complications and Prognosis

History and Symptoms

Physical Examination

Laboratory Findings

Chest X Ray

Medical Therapy

Primary Prevention

Future or Investigational Therapies

References