Paracoccidioidomycosis classification

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Danitza Lukac

Overview

Paracoccidioidomycosis may be classified according to Franco et al. in 1987 into: paracoccidioidomycosis infection, paracoccidioidomycosis disease, paracoccidioidomycosis associated with immunosupression and residual form (sequela). Based on the duration of symptoms, paracoccidioidomycosis disease may be classified into: acute, subacute or chronic. The chronic form can be subclassified into: unifocal and multifocal.[1][2]

Classification

  • Paracoccidioidomycosis infection: Patients have no clinical manifestations. Positive reaction to the paracoccidioidin skin test. [3]
  • Paracoccidioidomycosis disease
    • Acute form: Usually affects patients under 35 years. [3]
      • Moderate
      • Severe
    • Chronic form
      • Unifocal: Affects one organ or system. [3]
        • Mild
        • Moderate
        • Severe
      • Multifocal: Affects two or more organs or systems. [3]
        • Mild
        • Moderate
        • Severe
  • Paracoccidioidomycosis associated with immunosupression
  • Residual form (Sequela): Most frequently, chronic pulmonary obstructive disease. [3][2]

References

  1. de Oliveira HC, Assato PA, Marcos CM, Scorzoni L, de Paula E Silva AC, Da Silva Jde F; et al. (2015). "Paracoccidioides-host Interaction: An Overview on Recent Advances in the Paracoccidioidomycosis". Front Microbiol. 6: 1319. doi:10.3389/fmicb.2015.01319. PMC 4658449. PMID 26635779.
  2. 2.0 2.1 Fortes MR, Miot HA, Kurokawa CS, Marques ME, Marques SA (2011). "Immunology of paracoccidioidomycosis". An Bras Dermatol. 86 (3): 516–24. PMID 21738969.
  3. 3.0 3.1 3.2 3.3 3.4 Marques S. Paracoccidiodomicose: atualização epidemiológica, clínica, diagnóstica e terapêutica. An. Bras. Dermatol.2013;88(5):700-711