Splenic marginal zone lymphoma laboratory findings

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [2]; Associate Editor(s)-in-Chief: Sowminya Arikapudi, M.B,B.S. [3]

Overview

Laboratory tests for splenic marginal zone lymphoma include complete blood count (CBC), blood chemistry studies, cytogenetic analysis, flow cytometry, immunohistochemistry, genetic testing, FISH, PCR, and immunophenotyping.

Laboratory tests

Laboratory tests for splenic marginal zone lymphoma include:[1]

  • Peripheral Blood Smear
  • Circulating lymphoma cells show short villi at the poles of cells and plasmacytoid differentiation.[2]

References

  1. Splenic marginal zone lymphoma. Surveillance, Epidemiology, and End Results Program 2015. http://seer.cancer.gov/seertools/hemelymph/51f6cf57e3e27c3994bd5327/ Accessed on December 22,2015
  2. [1] Melo JV, Hegde U, Parreira A, Thompson I, Lampert IA, Catovsky D. "Splenic B cell lymphoma with circulating villous lymphocytes: differential diagnosis of B cell leukaemias with large spleens." J Clin Pathol. 1987 Jun;40(6):642-51. PMID: 3497180

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