WikiDoc MAKES NO GUARANTEE OF VALIDITY. WikiDoc is not a professional health care provider, nor is it a suitable replacement for a licensed healthcare provider. WikiDoc is intended to be an educational tool, not a tool for any form of healthcare delivery. The educational content on WikiDoc drug pages is based upon the FDA package insert, National Library of Medicine content and practice guidelines / consensus statements. WikiDoc does not promote the administration of any medication or device that is not consistent with its labeling. Please read our full disclaimer here.
Overview
Rose bengal sodium is a Diagnostic Agent that is FDA approved for the diagnosis of keratoconjunctivitis sicca, keratitis, abrasions or corrosions and routine ocular examinations. Common adverse reactions include stinging, irritation, discomfort.
Adult Indications and Dosage
FDA-Labeled Indications and Dosage (Adult)
Indications
Rose Bengal ophthalmic strips are used as a diagnostic agent in routine ocular examinations or when superficial conjunctiva or corneal tissue change is suspected. Rose Bengal ophthalmic strips can also serve as an effective aid in the diagnosis of keratoconjunctivitis sicca, keratitis, abrasions or corrosions as well as the detection of foreign bodies.
Direction
To ensure optimal staining and patient comfort, the GloStrip impregnated tip should be moistened with one or two drops of sterile, isotonic saline or irrigating solution before application. Shake off excess solution and touch conjunctiva or fornix as required with moistened tip. It is recommended that the patient blink several times after application.
Off-Label Use and Dosage (Adult)
Guideline-Supported Use
There is limited information regarding Off-Label Guideline-Supported Use of Rose bengal sodium in adult patients.
Non–Guideline-Supported Use
There is limited information regarding Off-Label Non–Guideline-Supported Use of Rose bengal sodium in adult patients.
Pediatric Indications and Dosage
FDA-Labeled Indications and Dosage (Pediatric)
There is limited information regarding FDA-Labeled Use of Rose bengal sodium in pediatric patients.
Off-Label Use and Dosage (Pediatric)
Guideline-Supported Use
There is limited information regarding Off-Label Guideline-Supported Use of Rose bengal sodium in pediatric patients.
Non–Guideline-Supported Use
There is limited information regarding Off-Label Non–Guideline-Supported Use of Rose bengal sodium in pediatric patients.
Contraindications
Known hypersensitivity to Rose Bengal.
Warnings
The contents may not be sterile if the individual strip package has been damaged or previously opened. This product is intended for external use only. Keep out of reach of children
Adverse Reactions
Clinical Trials Experience
There is limited information regarding Clinical Trial Experience of Rose bengal sodium in the drug label.
Body as a Whole
Cardiovascular
Digestive
Endocrine
Hematologic and Lymphatic
Metabolic and Nutritional
Musculoskeletal
Neurologic
Respiratory
Skin and Hypersensitivy Reactions
Special Senses
Urogenital
Miscellaneous
Postmarketing Experience
stinging, irritation, discomfort
Drug Interactions
There is limited information regarding Rose bengal sodium Drug Interactions in the drug label.
Australian Drug Evaluation Committee (ADEC) Pregnancy Category
There is no Australian Drug Evaluation Committee (ADEC) guidance on usage of Rose bengal sodium in women who are pregnant.
Labor and Delivery
There is no FDA guidance on use of Rose bengal sodium during labor and delivery.
Nursing Mothers
There is no FDA guidance on the use of Rose bengal sodium with respect to nursing mothers.
Pediatric Use
There is no FDA guidance on the use of Rose bengal sodium with respect to pediatric patients.
Geriatic Use
There is no FDA guidance on the use of Rose bengal sodium with respect to geriatric patients.
Gender
There is no FDA guidance on the use of Rose bengal sodium with respect to specific gender populations.
Race
There is no FDA guidance on the use of Rose bengal sodium with respect to specific racial populations.
Renal Impairment
There is no FDA guidance on the use of Rose bengal sodium in patients with renal impairment.
Hepatic Impairment
There is no FDA guidance on the use of Rose bengal sodium in patients with hepatic impairment.
Females of Reproductive Potential and Males
There is no FDA guidance on the use of Rose bengal sodium in women of reproductive potentials and males.
Immunocompromised Patients
There is no FDA guidance one the use of Rose bengal sodium in patients who are immunocompromised.
Administration and Monitoring
Administration
Ophthalmic
Monitoring
There is limited information regarding Monitoring of Rose bengal sodium in the drug label.
IV Compatibility
There is limited information regarding IV Compatibility of Rose bengal sodium in the drug label.
Overdosage
There is limited information regarding Overdose of Rose bengal sodium in the drug label.
Pharmacology
There is limited information regarding Rose bengal sodium Pharmacology in the drug label.
Mechanism of Action
As a vital stain, Rose Bengal stains both the nuclei and cell walls of dead or degenerated epithelial cells of the cornea and conjunctiva. Rose Bengal will also stain the mucus of the precorneal tear film.
Structure
Rose Bengal Ophthalmic Strips
diagnostic agent is for professional use only
Each strip is impregnated with 1.3 mg of Rose Bengal.