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Revision as of 18:20, 17 February 2015 by Gerald Chi (talk | contribs)
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References

See Also





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Treatment

Empiric therapy

Treatment options for high-risk patients

  • Intravenous antibiotic monotherapy in hospital (for uncomplicated cases)
  • Imipenem/cilastatin 500 mg IV every 6 h
  • Meropenem 1 gram IV every 8 h
  • Piperacillin/tazobactam 4.5 grams IV every 6 h
  • Cefepime 2 grams IV every 8 h
  • Ceftazidime 2 grams IV every 8 h

Treatment options for low-risk patients

  • Intravenous antibiotics at home
  • Daily long-acting intravenous agent ± oral therapy at home or office
  • Oral antibiotic combination therapy
  • Ciprofloxacin + amoxicillin/clavulanate both at 500 mg every 8 h
  • Moxifloxacin 400 mg every 24 h
  • Ciprofloxacin 500 mg every 8 h + clindamycin 600 mg every 8 h (for penicillin-allergic patients)
Criteria for oral antibiotics: no nausea or vomiting, patient able to tolerate oral medications, and patient not on prior fluoroquinolone prophylaxis.

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