Hodgkin's lymphoma staging
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sowminya Arikapudi, M.B,B.S. [2]
Overview
According to the Lugano classification, there are four stages of Hodgkin's lymphoma based on the number of nodes and extranodal involvement. According to the Cotswold's modification of the original Ann arbor staging system, there are four stages of Hodgkin's lymphoma.
Staging
According to the Lugano classification,[1]there are four stages of Hodgkin's lymphoma based on the number of nodes and extranodal involvement. According to the Cotswold's modification of the original Ann arbor staging system,[2][3] there are four stages of Hodgkin's lymphoma.
Staging for Hodgkin's lymphoma is provided in the following tables:
Stage | Involvement | Extranodal (E) status |
---|---|---|
Limited | ||
I | One node or a group of adjacent nodes | Single extranodal lesions without nodal involvement |
II | Two or more nodal groups on the same side of the diaphragm | Stage I or II by nodal extent with limited contiguous extranodal involvement |
II bulky* | II as above with "bulky" disease | Not applicable |
Advanced | ||
III | Nodes on both sides of the diaphragm; nodes above the diaphragm with spleen involvement | Not applicable |
IV | Additional noncontiguous extralymphatic involvement | Not applicable |
Stage | Involvement | |
---|---|---|
stage I | ||
I | One nodal group or lymphoid organ (e.g. spleen or thymus) | |
IE | One extranodal site | |
stage II | ||
II | Two or more nodal groups, same side of diaphragm | |
II E | Localised extranodal site with stage II criteria, both on the same side of the diaphragm | |
stage III | ||
III | Nodal groups on both sides of the diaphragm | |
III S (1) | With splenic involvement | |
III E (2) | With localised extranodal site | |
III SE | Both | |
stage IV | ||
IV | Disseminated involvement of one or more extralymphatic organ (e.g. lung, bone) +/- any nodal involvement | |
Additional staging variables | ||
X | Bulky nodal disease: nodal mass >1/3 of intra thoracic diameter or 10 cm in dimension | |
A | Asymptomatic | |
B | Presence of B symptoms (fever, night sweats and weight loss) | |
E | Extranodal: other than the lymph nodes or spread to tissues beyond, but nearby, the lymphatic tissues | |
S | Spleen | |
N | Lymph nodes | |
H | Liver | |
L | Lung | |
M | Bone marrow | |
O | Bone | |
D | Skin |
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Stage 1 Hodgkin's lymphoma
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Stage 2 Hodgkin's lymphoma
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Stage 3 Hodgkin's lymphoma
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Stage 4 Hodgkin's lymphoma
References
- ↑ Cheson, Bruce D.; Fisher, Richard I.; Barrington, Sally F.; Cavalli, Franco; Schwartz, Lawrence H.; Zucca, Emanuele; Lister, T. Andrew; Alliance, Australasian Leukaemia and Lymphoma Group; Eastern Cooperative Oncology Group; European Mantle Cell Lymphoma Consortium; Italian Lymphoma Foundation; European Organisation for Research; Treatment of Cancer/Dutch Hemato-Oncology Group; Grupo Español de Médula Ósea; German High-Grade Lymphoma Study Group; German Hodgkin's Study Group; Japanese Lymphorra Study Group; Lymphoma Study Association; NCIC Clinical Trials Group; Nordic Lymphoma Study Group; Southwest Oncology Group; United Kingdom National Cancer Research Institute (2014-09-20). "Recommendations for initial evaluation, staging, and response assessment of Hodgkin and non-Hodgkin lymphoma: the Lugano classification". Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology. 32 (27): 3059–3068. doi:10.1200/JCO.2013.54.8800. ISSN 1527-7755. PMID 25113753.
- ↑ "Radiopedia Lymphoma staging".
- ↑ "Canadian Cancer Society Stages of Hodgkin lymphoma".