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{{WBRQuestion
{{WBRQuestion
|QuestionAuthor={{Rim}}
|QuestionAuthor={{Rim}}, {{AJL}} {{Alison}}
|ExamType=USMLE Step 1
|ExamType=USMLE Step 1
|MainCategory=Biostatistics/ Epidemiology
|MainCategory=Biostatistics/ Epidemiology
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|MainCategory=Biostatistics/ Epidemiology
|MainCategory=Biostatistics/ Epidemiology
|SubCategory=Renal
|SubCategory=Renal
|Prompt=A case-control study investigating the association between the current use of non-steroidal anti-inflammatory drugs (NSAIDs), for more than 1 year, and impaired renal function. 2000 men and women above the age of 50 are surveyed.  The results of the study have been categorized in the following table.  What is the odds ratio for having renal impairment among patients who have a history of NSAID use versus those who do not use NSAIDs?
|Prompt=A case-control study investigating the association between the current use of non-steroidal anti-inflammatory drugs (NSAIDs), for more than 1 year, and impaired renal function. 2000 males and females over the age of 50 are surveyed and the results of the study have been categorized in the following table.  Which of the following numbers represents the odds ratio for renal impairment among patients with a history of NSAID use, versus those without a history of NSAID use?


[[Image:NSAID use WBR.png|300px]]
[[Image:NSAID use WBR.png|300px]]
|Explanation=[[Image:NSAID use WBR odds ratio.png|300px]]
|Explanation=[[Image:NSAID use WBR odds ratio.png|300px]]


Odds ratio (OR) is calculated using the equation:  
The odds ratio (OR) in this scenario is calculated using the equation:  
OR = ad/bc = (800 x 300)/(400 x 500) = 240000/200000 = 1.2
OR = ad/bc = (800 x 300)/(400 x 500) = 240000/200000 = 1.2


Education Objective:
|EducationalObjectives= The odds ratio is calculated using the equation: OR = ad/bc
Odds ratio is calculated using the equation: OR = ad/bc
|References= First Aid 2014 page 50
 
|AnswerA=0.041
|AnswerA=0.041
|AnswerAExp=0.041 is the attributable risk.  It is calculated by the following equation:  
|AnswerAExp=0.041 represents the attributable risk, calculated using the following equation:  
Attributable Risk = (a/[a+b]) – (c/[c+d])
Attributable Risk = (a/[a+b]) – (c/[c+d])
|AnswerB=0.500
|AnswerB=0.500
|AnswerBExp=0.500 does not correspond to any value.
|AnswerBExp=0.500 does not correspond to any relevant value.
|AnswerC=1.066
|AnswerC=1.066
|AnswerCExp=1.066 is the relative risk (RR).  It is used in cohort studies.  It is calculated by the following equation:
|AnswerCExp=1.066 represents the relative risk (RR), often used in cohort studies, calculated with the following equation:
RR = (a/[a+b]) / (c/[c+d])
RR = (a/[a+b]) / (c/[c+d])
|AnswerD=1.200
|AnswerD=1.200
|AnswerDExp=1.200 correctly corresponds to the odds ratio.
|AnswerDExp=1.200 correctly corresponds to the odds ratio.
|AnswerE=1.500
|AnswerE=1.500
|AnswerEExp=1.500 does not correspond to any value.
|AnswerEExp=1.500 does not correspond to any relevant value.
|RightAnswer=D
|RightAnswer=D
|Approved=No
|WBRKeyword= odds ratio, OR, formulas, formula, case-control, equation
|Approved=Yes
}}
}}

Revision as of 15:35, 17 July 2014

 
Author [[PageAuthor::Rim Halaby, M.D. [1], Alison Leibowitz [2] (Reviewed by Alison Leibowitz)]]
Exam Type ExamType::USMLE Step 1
Main Category MainCategory::Biostatistics/ Epidemiology
Sub Category SubCategory::Renal
Prompt [[Prompt::A case-control study investigating the association between the current use of non-steroidal anti-inflammatory drugs (NSAIDs), for more than 1 year, and impaired renal function. 2000 males and females over the age of 50 are surveyed and the results of the study have been categorized in the following table. Which of the following numbers represents the odds ratio for renal impairment among patients with a history of NSAID use, versus those without a history of NSAID use?

]]

Answer A AnswerA::0.041
Answer A Explanation [[AnswerAExp::0.041 represents the attributable risk, calculated using the following equation:

Attributable Risk = (a/[a+b]) – (c/[c+d])]]

Answer B AnswerB::0.500
Answer B Explanation AnswerBExp::0.500 does not correspond to any relevant value.
Answer C AnswerC::1.066
Answer C Explanation [[AnswerCExp::1.066 represents the relative risk (RR), often used in cohort studies, calculated with the following equation:

RR = (a/[a+b]) / (c/[c+d])]]

Answer D AnswerD::1.200
Answer D Explanation AnswerDExp::1.200 correctly corresponds to the odds ratio.
Answer E AnswerE::1.500
Answer E Explanation AnswerEExp::1.500 does not correspond to any relevant value.
Right Answer RightAnswer::D
Explanation [[Explanation::

The odds ratio (OR) in this scenario is calculated using the equation: OR = ad/bc = (800 x 300)/(400 x 500) = 240000/200000 = 1.2
Educational Objective: The odds ratio is calculated using the equation: OR = ad/bc
References: First Aid 2014 page 50]]

Approved Approved::Yes
Keyword WBRKeyword::odds ratio, WBRKeyword::OR, WBRKeyword::formulas, WBRKeyword::formula, WBRKeyword::case-control, WBRKeyword::equation
Linked Question Linked::
Order in Linked Questions LinkedOrder::