Sandbox john2

In Progress

Chemoprophylaxis Chemoprophylaxis in chronic infectious diseases such as, tuberculosis has an established benefit, particularly when given to persons who are known to be at a higher risk of developing leprosy. The immediate contacts of a case of leprosy, especially multibacillary, are known to have a higher risk of developing the disease than compared to the general population. It is important, therefore, to consider possible interventions to prevent the occurrence of leprosy among household contacts. However, there must be robust trial evidence to demonstrate that the drug/s used for chemoprophylaxis are safe, effective and cost-efficient in terms of the number of new cases prevented. On account of lack of consistent results from various studies using various drugs (dapsone, acedapsone, rifampicin) it is too premature to advise chemoprophylaxis as a public health measure. Further research is needed to use this as a routine tool to prevent the occurrence of disease among contacts.

Random notes

---

---