Methyldopa injection description: Difference between revisions
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Methyldopate Hydrochloride ......... 50 mg | Methyldopate Hydrochloride ......... 50 mg | ||
Citric Acid (Anhydrous) ................. 5 mg | Citric Acid (Anhydrous) ................. 5 mg | ||
Edetate Disodium ......................... 0.5 mg | Edetate Disodium ......................... 0.5 mg | ||
Monothioglycerol ........................... 2 mg | Monothioglycerol ........................... 2 mg | ||
Water for Injection ................q.s. to 1 mL | Water for Injection ................q.s. to 1 mL | ||
Revision as of 18:28, 10 March 2014
| Methyldopa |
|---|
| Methyldopa tablet® FDA Package Insert |
| Indications and Usage |
| Dosage and Administration |
| Contraindications |
| Warnings |
| Precautions |
| Adverse Reactions |
| Drug Interactions |
| Use in Specific Populations |
| Overdosage |
| Description |
| Clinical Pharmacology |
| Nonclinical Toxicology |
| How Supplied/Storage and Handling |
| Labels and Packages |
| Methyldopa injection® FDA Package Insert |
| Indications and Usage |
| Dosage and Administration |
| Contraindications |
| Warnings |
| Precautions |
| Adverse Reactions |
| Drug Interactions |
| Use in Specific Populations |
| Overdosage |
| Description |
| Clinical Pharmacology |
| Nonclinical Toxicology |
| How Supplied/Storage and Handling |
| Labels and Packages |
| Clinical Trials on Methyldopa |
| ClinicalTrials.gov |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Abdurahman Khalil, M.D. [2]
DESCRIPTION
Methyldopate HCl Injection, USP, is an antihypertensive agent for intravenous use. Sterile, nonpyrogenic.
Methyldopate hydrochloride [levo-3-(3,4-dihydroxyphenyl)-2-methylalanine, ethyl ester hydrochloride] is the ethyl ester of methyldopa, supplied as the hydrochloride salt with a molecular weight of 275.73. Methyldopate hydrochloride is more soluble and stable in solution than methyldopa and is the preferred form for intravenous use.
The molecular formula for Methyldopate hydrochloride is C12H17NO4·HCl and the structural formula is:
Each mL contains:
Methyldopate Hydrochloride ......... 50 mg
Citric Acid (Anhydrous) ................. 5 mg
Edetate Disodium ......................... 0.5 mg
Monothioglycerol ........................... 2 mg
Water for Injection ................q.s. to 1 mL
Methylparaben 1.5 mg and Propylparaben 0.2 mg added as preservatives, Sodium Bisulfite 3.2 mg added as an antioxidant. pH adjusted with Sodium Hydroxide and/or Hydrochloric Acid.[1]
References
- ↑ "METHYLDOPATE HYDROCHLORIDE INJECTION, SOLUTION [AMERICAN REGENT, INC.]". Retrieved 10 March 2014.