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{{familytree/start}}
{| class="wikitable"
{{familytree | | | | | | A01 |-|-|-|-|-|-|-|-|-|-|.| | | | | | | | | | | | | | | |A01=<div style="float: left; text-align: left; line-height: 150%; height: 17em; width: 28em "> ❑ '''High Quality CPR'''<br> '''Compressions:'''
 
: Push hard (>2 inches) & fast (>100/min)
|-
: Minimize interruptions; rotate compressor every 2 mins <br>
 
'''Airway:''' Open airway <br>
! Drug 
'''Breathing:'''
 
: Pressure ventilation; 2 breaths every 30 compressions
! Route of administration
: Bagmask also acceptable
 
----
! Dose titration
❑ '''Attach monitor/defibrillator'''<br> ❑ '''Check rhythm'''
 
</div>}}
! Dose range
{{familytree | | | | | | |!| | | | | | | | | | | |!| | | | | | | | | | | | | | | | }}
 
{{familytree | | | | | | |!| | | | | | | | | | | |!| | | | | | | | | | | | | | | | }}
! Side effects
{{familytree |border=0 | | | | | | C01 | | | C03 | | | | | C02 | | | | | | | | | | | | | |C01= '''↓''' |C02= '''↑''' |C03= Continous CPR every 2 mins}}
 
{{familytree |border=0 | | | | | | D01 | | | | | | | | | | D02 | | | | | | | | | | | | | |D01= '''↓''' |D02= '''↑''' }}
|-
{{familytree | | | | | | |!| | | | | | | | | | | |!| | | | | | | | | | | | | | | | }}
| Epoprostenol
{{familytree | | | | | | |!| | | | | | | | | | | |!| | | | | | | | | | | | | | | | }}
 
{{familytree | | | | | | |!| | | | | E01 | | | | |!| | | | | | | | | | | | | | | |E01=<div style="float: left; text-align: left; line-height: 150%; width: 30em; height: 33em ">'''Drug Therapy''' <br> ❑ Establish IV/IO access (do not interrupt CPR) <br> ❑ Vasopressor:
| Intravenous infusion
:♦ '''[[Epinephrine]]''' '''1 mg IV q3-5 min''' (or 2 mg via ETT)
 
:♦ '''[[Vasopressin]]''' '''40 U''' can replace 2nd or 3rd doses of epinephrine)
| 2 ng/kg/min every 10 to 15 min
❑ Antiarrythmic:
 
:♦ '''[[Amiodarone]]''' '''300 mg''' IV bolus + '''150 mg 3-5 min later'''
| 2 to 10 ng/kg/min
:♦ '''[[lidocaine]]''' '''1-1.5 mg/Kg IV, max 3mg/Kg'''
 
----
| Headache, nausea, lightheadedness
'''Consider advanced airway:'''<br> ❑ Endotracheal intubation or supraglottic advanced airway <br> ❑ Assess : Bilateral chest expansion & breath sounds <br> ❑ Check tube placement <br> ❑ 8-10 breaths per min with continous compressions
 
----
|-
'''Treat reversible causes:'''<br>
 
❑ [[Hypovolemia]]: Volume    ❑ [[Tension Pneumothorax]]<br>
| Adenosine
❑ [[Hypoxia]]: Oxygenate      ❑ [[cardiac tamponade|Tamponade]]: Pericardiocentesis<br>
 
❑ H+ ions: NaHCo3            ❑ Toxins<br>
 
❑ Hypo/Hyper K: Replace  ❑ Thromb. ([[Pulmonary embolism|PE]])<br>
| Intravenous infusion
❑ [[Hypothermia]]: Warm        ❑ Thromb. ([[Acute coronary syndrome|ACS]])
 
</div>}}
 
{{familytree | | | | | | |!| | | | | | | | | | | |!| | | | | | | | | | | | | | | | }}
| 50 mcg/kg/min every 2 min
{{familytree | | | | | | |!| | | | | | | | | | | |!| | | | | | | | | | | | | | | | }}
 
{{familytree |border=0 | | | | | | F02 | | | F03 | | | | | F01 | | | | | | | | | | | | | | |F01= '''↑'''| F02= '''↓''' |F03= Continous CPR every 2 mins}}
 
{{familytree |border=0 | | | | | | G02 | | | | | | | | | | G01 | | | | | | | | | | | | | | |G01= '''↑'''| G02= '''↓'''}}
| 50 to 250 mcg/kg/min  
{{familytree | | | | | | |!| | | | | | | | | | | |!| | | | | | | | | | | | | | | | }}
 
{{familytree | | | | | | |!| | | | | | | | | | | |!| | | | | | | | | | | | | | | | }}
 
{{familytree | | | | | | K01 |-|-|-|-|-|-|-|-|-|-|'| | | | | | | | | | | | | | | |K01=<div style="float: left; text-align: left; line-height: 150% ">❑'''Shockable rhythm? ([[VF]]/[[Pulseless VT]])''' <br> Deliver shock (120-200 J biphasic; 360 J monophasic)
| Dyspnea, chest pain, AV block
----
 
❑ '''Rhythm not shockable? ([[Asystole]]/[[PEA]])'''<br> Resume CPR
 
----
|-
❑ On Return of spontaneous circulation (ROSC)
 
:::::: ↓
| Nitric Oxide
:::: [[Post-arrest care]] </div>}}
 
{{familytree | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | }}
 
{{familytree/end}}
| Inhaled
 
 
| None
 
 
| 10 to 80 ppm
 
| Increased left heart filling pressure in susceptible patients
 
|-
 
|}

Revision as of 18:20, 9 January 2014

Drug Route of administration Dose titration Dose range Side effects
Epoprostenol Intravenous infusion 2 ng/kg/min every 10 to 15 min 2 to 10 ng/kg/min Headache, nausea, lightheadedness
Adenosine


Intravenous infusion


50 mcg/kg/min every 2 min


50 to 250 mcg/kg/min


Dyspnea, chest pain, AV block


Nitric Oxide


Inhaled


None


10 to 80 ppm Increased left heart filling pressure in susceptible patients