Deep vein thrombosis resident survival guide: Difference between revisions

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(/* Diagnostic approach{{cite journal| author=Bates SM, Jaeschke R, Stevens SM, Goodacre S, Wells PS, Stevenson MD et al.| title=Diagnosis of DVT: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence...)
(/* Diagnostic approach{{cite journal| author=Bates SM, Jaeschke R, Stevens SM, Goodacre S, Wells PS, Stevenson MD et al.| title=Diagnosis of DVT: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence...)
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'''High probability''':<br> >3 major points+ no alternative diagnosis<br>or 2 major points + 2 minor points + no alternative diagnosis.<br>
'''High probability''':<br> >3 major points+ no alternative diagnosis<br>or 2 major points + 2 minor points + no alternative diagnosis.<br>
'''Low probability''': <br> 1 major point +≥2 minor + alternative diagnosis<br> or 1 major + ≥1 minor + no alternative diagnosis<br> or no major points+ irrespective of minor points +irrespective of diagnosis.<br>
'''Low probability''': <br> 1 major point +≥2 minor + alternative diagnosis<br> or 1 major + ≥1 minor + no alternative diagnosis<br> or no major points+ irrespective of minor points +irrespective of diagnosis.<br>
'''Moderate probability''': neither high or low probability.<ref name="pmid9428249">{{cite journal| author=Wells PS, Anderson DR, Bormanis J, Guy F, Mitchell M, Gray L et al.| title=Value of assessment of pretest probability of deep-vein thrombosis in clinical management. | journal=Lancet | year= 1997 | volume= 350 | issue= 9094 | pages= 1795-8 | pmid=9428249 | doi=10.1016/S0140-6736(97)08140-3 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9428249  }} </ref>
'''Moderate probability''':<br> neither high or low probability.<ref name="pmid9428249">{{cite journal| author=Wells PS, Anderson DR, Bormanis J, Guy F, Mitchell M, Gray L et al.| title=Value of assessment of pretest probability of deep-vein thrombosis in clinical management. | journal=Lancet | year= 1997 | volume= 350 | issue= 9094 | pages= 1795-8 | pmid=9428249 | doi=10.1016/S0140-6736(97)08140-3 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9428249  }} </ref>


==Management==
==Management==

Revision as of 17:13, 2 December 2013

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Definition

Deep vein thrombosis (also known as deep venous thrombosis or DVT and colloquially referred to as economy class syndrome) is the formation of a blood clot ("thrombus") in a deep vein. The risk is significantly increased if the thrombus embolizes to the lungs, causing pulmonary embolism.

Causes

Life Threatening Causes

Common Causes

  • Long term immobility
  • Clotting disorders
  • Cardiac failure
  • Hip replacement
  • Estrogen in OCP and HRT
  • Nephrotic syndrome
  • Obesity
  • Pregnancy

Diagnostic approach[1]

 
 
 
 
 
 
 
 
 
 
Pretest Probability of DVT
Major points
1-Active cancer
2-Paralysis,paresis or plastic
immobilization of leg or foot
3-Recent bed rest >3 days
or major surgery in the last 4 weeks or both
4-Calf or thigh swelling 5->3 cm calf swelling
below the tibial tuberosity
5-Strong F/H of DVT
Minor points
1-H/O recent trauma to the suspected leg
2-Pitting edema in the suspected leg
3-Dilated superficial veins in the suspected leg
4-Hospitalization in the last 6 months
5-Erythema
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Low probability*
 
 
 
 
 
Moderate probability*
 
 
 
 
 
 
 
 
 
 
High probability*
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
D-Dimer
 
 
 
 
 
D-Dimer
 
 
 
 
 
 
 
 
 
 
U/S
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Negative
 
Positive
 
Negative
 
Positive
 
 
 
 
 
Negative
 
 
 
Positive
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
No DVT
 
U/S
 
No DVT
 
U/S
 
 
 
Repeat in 7 days
 
D-Dimer
 
Treat
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Negative
 
Positive
 
Negative
 
Positive
 
 
 
Negative
 
 
Positive
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
No DVT
 
Treat
 
Repeat in 7 days
 
Treat
 
 
 
No DVT
 
Repeat in 7 days
 
U/S
 

High probability:
>3 major points+ no alternative diagnosis
or 2 major points + 2 minor points + no alternative diagnosis.
Low probability:
1 major point +≥2 minor + alternative diagnosis
or 1 major + ≥1 minor + no alternative diagnosis
or no major points+ irrespective of minor points +irrespective of diagnosis.
Moderate probability:
neither high or low probability.[2]

Management

Do's and Don'ts

References

  1. Bates SM, Jaeschke R, Stevens SM, Goodacre S, Wells PS, Stevenson MD; et al. (2012). "Diagnosis of DVT: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines". Chest. 141 (2 Suppl): e351S–418S. doi:10.1378/chest.11-2299. PMC 3278048. PMID 22315267.
  2. Wells PS, Anderson DR, Bormanis J, Guy F, Mitchell M, Gray L; et al. (1997). "Value of assessment of pretest probability of deep-vein thrombosis in clinical management". Lancet. 350 (9094): 1795–8. doi:10.1016/S0140-6736(97)08140-3. PMID 9428249.

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