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==Overview==
==Overview==
'''Ventricular remodeling''' refers to the changes in size, shape, and function of the heart after injury to the [[left ventricle]].  The injury is typically due to [[acute myocardial infarction]] (usually transmural or ST segment elevation infarction), but may be from a number of causes that result in increased pressure or volume overload (forms of strain) on the heart. Chronic [[hypertension]], [[congenital heart disease]] with intracardiac shunting, and [[valvular heart disease]] may also lead to remodeling. After the insult occurs, a series of histopathological and structural changes occur in the left ventricular myocardium that lead to progressive decline in left ventricular performance.  Ultimately, ventricular remodeling may result in diminished contractile ([[systolic]]) function and reduced [[stroke volume]].
Medically speaking, "ventricular remodeling" implies a decline in function (even though the word "remodeling" usually implies improvement). The term "reverse remodeling" in cardiology implies an improvement in ventricular mechanics and function after a remote injury.


==Classification==
==Classification==

Revision as of 17:54, 26 November 2013

Ventricular Remodeling

Home

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Ventricular Remodeling From Other Conditions

Epidemiology and Demographics

Risk Factors

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms

Physical Examination

Laboratory Findings

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Future or Investigational Therapies

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Ventricular remodeling refers to the changes in size, shape, and function of the heart after injury to the left ventricle. The injury is typically due to acute myocardial infarction (usually transmural or ST segment elevation infarction), but may be from a number of causes that result in increased pressure or volume overload (forms of strain) on the heart. Chronic hypertension, congenital heart disease with intracardiac shunting, and valvular heart disease may also lead to remodeling. After the insult occurs, a series of histopathological and structural changes occur in the left ventricular myocardium that lead to progressive decline in left ventricular performance. Ultimately, ventricular remodeling may result in diminished contractile (systolic) function and reduced stroke volume.

Medically speaking, "ventricular remodeling" implies a decline in function (even though the word "remodeling" usually implies improvement). The term "reverse remodeling" in cardiology implies an improvement in ventricular mechanics and function after a remote injury.

Classification

Pathophysiology

Causes

Differentiating Ventricular Remodeling From Other Conditions

Epidemiology and Demographics

Risk Factors

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms

Physical Examination

Laboratory Findings

Other Imaging Findings

Treatment

References