Loa loa filaria: Difference between revisions
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==Overview== | ==Overview== | ||
'''''Loa loa''''' is the [[filaria]]l [[nematode]] (roundworm) [[species]] that causes [[Loa loa filariasis]]. Its geographic distribution includes Africa and India.<ref name="FoP">Schmidt, Gerald et al. "Foundations of Parasitology". 7th ed. McGraw Hill, New York, NY, 2005.</ref> | '''''Loa loa''''' is the [[filaria]]l [[nematode]] (roundworm) [[species]] that causes [[Loa loa filariasis]]. Its geographic distribution includes Africa and India.<ref name="FoP">Schmidt, Gerald et al. "Foundations of Parasitology". 7th ed. McGraw Hill, New York, NY, 2005.</ref> | ||
''L. loa'' is one of three parasitic filarial nematodes that cause | ''L. loa'' is one of three parasitic filarial nematodes that cause subcutaneous filariasis in humans. The two other filarial nematodes are ''Mansonella streptocerca'' and ''Onchocerca volvulus'' (causes [[river blindness]]). | ||
Maturing [[larva]]e and adults of the | Maturing [[larva]]e and adults of the eye worm occupy the [[subcutaneous]] layer of the [[skin]] ; the fat layer; of humans, causing disease. The young larvae develop in [[horseflies]] of the [[genus]] ''[[Chrysops]]'' (deer flies, yellow flies), including the species ''[[Chrysops dimidiata|C. dimidiata]]'' and ''[[Chrysops silacea|C. silacea]]'', which infect humans by biting them. | ||
==Pathophysiology== | ==Pathophysiology== | ||
===Morphology=== | ===Morphology=== | ||
Revision as of 16:52, 27 December 2012
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Filaria loa Cobbold, 1864 |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Loa loa is the filarial nematode (roundworm) species that causes Loa loa filariasis. Its geographic distribution includes Africa and India.[1] L. loa is one of three parasitic filarial nematodes that cause subcutaneous filariasis in humans. The two other filarial nematodes are Mansonella streptocerca and Onchocerca volvulus (causes river blindness). Maturing larvae and adults of the eye worm occupy the subcutaneous layer of the skin ; the fat layer; of humans, causing disease. The young larvae develop in horseflies of the genus Chrysops (deer flies, yellow flies), including the species C. dimidiata and C. silacea, which infect humans by biting them.
Pathophysiology
Morphology
Loa loa worms have a simple body including a head, body, and tail. Males range from 20mm to 34mm long and 350μm to 430μm wide. Females range from 20mm to 70mm long and are about 425μm wide.[1]
Life cycle
Three species involved in the life cycle include the parasite Loa loa, the fly vector, and the human host:[2]
- A vector fly bites an infected human host and ingests microfilariae.
- Microfilariae move to the fat body of the insect host.
- Microfilariae develop into first stage larvae, then third stage larvae.
- Third stage larvae (infective) travel to the proboscis of fly.
- An infected vector fly bites an uninfected human host and the third stage larvae penetrates the skin and enters human subcutaneous tissue.
- Larvae mature into adults, who produce microfilariae that have been found in spinal fluid, urine, peripheral blood, and lungs.
References
- ↑ 1.0 1.1 Schmidt, Gerald et al. "Foundations of Parasitology". 7th ed. McGraw Hill, New York, NY, 2005.
- ↑ "Filariasis". Parasites and Health. Center for Disease Control.
- Taxonomy Browser: Loa Loa. National Center for Biotechnology Information (NCBI).
ar:لوا لوائية cs:Vlasovec oční de:Loa loa hu:Szemféreg sv:Loiasis de:Loa loa