Atrial septal defect complications: Difference between revisions

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===Atrial septal defect and atrial fibrillation===
===Atrial septal defect and atrial fibrillation===
50-60% of atrial septal defect patients over the age of 40 will develop [[atrial fibrillation]]. Late-onset [[atrial fibrillation]] is associated with both [[morbidity]] and [[mortality]]. [[Anticoagulation]] may lower the [[mortality]] risk. Closing ASD does not prevent occurrence of atrial fibrillation in these patients. But early closure of ASD lowers the risk of getting atrial fibrillation.
50-60% of atrial septal defect patients over the age of 40 will develop [[atrial fibrillation]]. Late-onset [[atrial fibrillation]] is associated with both [[morbidity]] and [[mortality]]. [[Anticoagulation]] may lower the [[mortality]] risk. Closing an ASD at this point does not prevent occurrence of atrial fibrillation in these patients. But early closure of ASD lowers the risk of developing atrial fibrillation.


===Atrial septal defect and pulmonary hypertension===
===Atrial septal defect and pulmonary hypertension===

Revision as of 00:03, 18 October 2012

Atrial Septal Defect Microchapters

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Overview

Anatomy

Classification

Ostium Secundum Atrial Septal Defect
Ostium Primum Atrial Septal Defect
Sinus Venosus Atrial Septal Defect
Coronary Sinus
Patent Foramen Ovale
Common or Single Atrium

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Priyamvada Singh, M.B.B.S. [2]; Cafer Zorkun, M.D., Ph.D. [3] Assistant Editor(s)-In-Chief: Kristin Feeney, B.S. [4]

Overview

Atrial septal defect is associated with complications such as atrial fibrillation, pulmonary hypertension, heart failure, and stroke.

Atrial septal defect and atrial fibrillation

50-60% of atrial septal defect patients over the age of 40 will develop atrial fibrillation. Late-onset atrial fibrillation is associated with both morbidity and mortality. Anticoagulation may lower the mortality risk. Closing an ASD at this point does not prevent occurrence of atrial fibrillation in these patients. But early closure of ASD lowers the risk of developing atrial fibrillation.

Atrial septal defect and pulmonary hypertension

15-20% of atrial septal defect patients develop pulmonary hypertension. Although rare in children and adolescents, pulmonary arterial hypertension is observed in approximately 50% of patients over the age of 40. The development of Eisenmenger's syndrome can result in reversal of the original left-to-right shunt which may switch to become a right-to-left shunt. Right-to-left shunting can in turn lead to deoxygenation (hypoxemia and cyanosis).

Atrial septal defect and right heart failure

Atrial septal defect is associated with left-to-right shunting which in turn may be associated with right ventricular volume overload. Patients may experience right heart failure as a result of right ventricular volume overload.

Atrial septal defect and stroke

Even without surgery, as many as 5-10% of all atrial septal defect patients experience thromboembolic events such as stroke and transient ischemic attack. Paradoxical emboli in atrial septal defect patients is not correlated with defect size and can occur in all ASD patients.

References

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