Atrial septal defect complications: Difference between revisions
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While atrial septal defect may serve as the underlying cause, many patients are susceptible to developing secondary conditions or comorbidities such as [[atrial fibrillation]], [[pulmonary hypertension]], [[heart failure]], and [[stroke]]. | While atrial septal defect may serve as the underlying cause, many patients are susceptible to developing secondary conditions or comorbidities such as [[atrial fibrillation]], [[pulmonary hypertension]], [[heart failure]], and [[stroke]]. | ||
==Complications involving comorbidity== | |||
Many atrial septal defect patients are at risk for developing comorbid complexes with the following conditions: | Many atrial septal defect patients are at risk for developing comorbid complexes with the following conditions: | ||
===Atrial septal defect and atrial fibrillation=== | |||
50-60% of atrial septal defect patients over the age of 40 experience [[atrial fibrillation]] issues. This late-onset is correlated as a major cause in [[morbidity]] and [[mortality]]. Some research suggests that pharmacologic therapy such as [[anticoagulants]] can assist with lower [[mortality]] risks associated with [[atrial flutter]]. | 50-60% of atrial septal defect patients over the age of 40 experience [[atrial fibrillation]] issues. This late-onset is correlated as a major cause in [[morbidity]] and [[mortality]]. Some research suggests that pharmacologic therapy such as [[anticoagulants]] can assist with lower [[mortality]] risks associated with [[atrial flutter]]. | ||
===Atrial septal defect and pulmonary hypertension=== | |||
15-20% of atrial septal defect patients develop [[pulmonary hypertension]]. Characteristically rare during youth, pulmonary hypertension has been observed in 50% of patients over the age of 40. In particular, [[Eisenmenger syndrome]] patients are at risk for severe pulmonary obstruction and can result in significant reversal of blood shunting from right-to-left. This can lead to systemic circulation conditions such as [[hypoxemia]] and [[cyanosis]]. | 15-20% of atrial septal defect patients develop [[pulmonary hypertension]]. Characteristically rare during youth, pulmonary hypertension has been observed in 50% of patients over the age of 40. In particular, [[Eisenmenger syndrome]] patients are at risk for severe pulmonary obstruction and can result in significant reversal of blood shunting from right-to-left. This can lead to systemic circulation conditions such as [[hypoxemia]] and [[cyanosis]]. | ||
===Atrial septal defect and right heart failure=== | |||
Due to the nature of the defect, atrial septal defect patients of all ages experience strain on the right-heart complex. Patients may experience [[heart failure]] as a result of the cardiac volume overload the right side of the heart experiences during left-to-right shunting. | Due to the nature of the defect, atrial septal defect patients of all ages experience strain on the right-heart complex. Patients may experience [[heart failure]] as a result of the cardiac volume overload the right side of the heart experiences during left-to-right shunting. | ||
===Atrial septal defect and stroke=== | |||
Even without surgery, as many as 5-10% of all atrial septal defect patients experience thromboembolic events such as [[stroke]] and [[transient ischemia]]. Research suggests that [[paradoxical emboli]] in atrial septal defect patients is mutually exclusive of defect size and can potentially occur in all patients. | Even without surgery, as many as 5-10% of all atrial septal defect patients experience thromboembolic events such as [[stroke]] and [[transient ischemia]]. Research suggests that [[paradoxical emboli]] in atrial septal defect patients is mutually exclusive of defect size and can potentially occur in all patients. | ||
Revision as of 13:20, 26 July 2011
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Atrial Septal Defect Microchapters | |
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Treatment | |
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Surgery | |
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Special Scenarios | |
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Case Studies | |
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Atrial septal defect complications On the Web | |
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American Roentgen Ray Society Images of Atrial septal defect complications | |
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Risk calculators and risk factors for Atrial septal defect complications | |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1], Claudia Hochberg, M.D.
Associate Editors-In-Chief: Cafer Zorkun, M.D., Ph.D. [2]; Keri Shafer, M.D. [3]; Priyamvada Singh, MBBS [[4]]
Assistant Editor-In-Chief: Kristin Feeney, B.S. [[5]]
Overview
While atrial septal defect may serve as the underlying cause, many patients are susceptible to developing secondary conditions or comorbidities such as atrial fibrillation, pulmonary hypertension, heart failure, and stroke.
Complications involving comorbidity
Many atrial septal defect patients are at risk for developing comorbid complexes with the following conditions:
Atrial septal defect and atrial fibrillation
50-60% of atrial septal defect patients over the age of 40 experience atrial fibrillation issues. This late-onset is correlated as a major cause in morbidity and mortality. Some research suggests that pharmacologic therapy such as anticoagulants can assist with lower mortality risks associated with atrial flutter.
Atrial septal defect and pulmonary hypertension
15-20% of atrial septal defect patients develop pulmonary hypertension. Characteristically rare during youth, pulmonary hypertension has been observed in 50% of patients over the age of 40. In particular, Eisenmenger syndrome patients are at risk for severe pulmonary obstruction and can result in significant reversal of blood shunting from right-to-left. This can lead to systemic circulation conditions such as hypoxemia and cyanosis.
Atrial septal defect and right heart failure
Due to the nature of the defect, atrial septal defect patients of all ages experience strain on the right-heart complex. Patients may experience heart failure as a result of the cardiac volume overload the right side of the heart experiences during left-to-right shunting.
Atrial septal defect and stroke
Even without surgery, as many as 5-10% of all atrial septal defect patients experience thromboembolic events such as stroke and transient ischemia. Research suggests that paradoxical emboli in atrial septal defect patients is mutually exclusive of defect size and can potentially occur in all patients.