Amiodarone overdose: Difference between revisions
Jump to navigation
Jump to search
m (Protected "Amiodarone overdose" [edit=sysop:move=sysop]) |
No edit summary |
||
| Line 1: | Line 1: | ||
{{CMG}} | {{CMG}} | ||
There have been cases, some fatal, of Amiodarone overdose. | There have been cases, some fatal, of Amiodarone overdose. | ||
| Line 6: | Line 7: | ||
The acute oral LD<sub>50</sub> of Amiodarone HCl in mice and rats is greater than 3,000 mg/kg. | The acute oral LD<sub>50</sub> of Amiodarone HCl in mice and rats is greater than 3,000 mg/kg. | ||
{{FDA}} | |||
[[Category:Drugs]] | |||
Revision as of 20:19, 8 January 2009
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
There have been cases, some fatal, of Amiodarone overdose.
In addition to general supportive measures, the patient's cardiac rhythm and blood pressure should be monitored, and if bradycardia ensues, a β-adrenergic agonist or a pacemaker may be used. Hypotension with inadequate tissue perfusion should be treated with positive inotropic and/or vasopressor agents. Neither Amiodarone nor its metabolite is dialyzable.
The acute oral LD50 of Amiodarone HCl in mice and rats is greater than 3,000 mg/kg.
Adapted from the FDA Package Insert.