Thin basement membrane disease diagnostic study of choice: Difference between revisions
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==Overview== | ==Overview== | ||
Renal biopsy is the gold standard test for TBMD. | Renal biopsy is the gold standard test for TBMD. | ||
==Diagnostic study of choice== | ==Diagnostic study of choice== | ||
The following result of Renal biopsy is confirmatory of TBMD: | The following result of Renal biopsy is confirmatory of TBMD: | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Renal biopsy is the gold standard test for TBMD.
Diagnostic study of choice
The following result of Renal biopsy is confirmatory of TBMD:
- Erythrocytes in between renal tubules ad bowman's membrane[1]
- Diffuse thinning of GBM in electron microscopy in around 50% of population with TBMD.[2] Occassionally, segmental thinning of GBM is present in TBMD.[3]
- Minimal glomerular change or mesangial expansion may be present on light microscopy.[4]
- Absence of any other Glomerular pathology.
References
- ↑ Bailey RR (July 1990). "Familial haematuria due to thin basement membrane nephropathy". N. Z. Med. J. 103 (893): 312–3. PMID 2371004.
- ↑ Foster K, Markowitz GS, D'Agati VD (May 2005). "Pathology of thin basement membrane nephropathy". Semin. Nephrol. 25 (3): 149–58. doi:10.1016/j.semnephrol.2005.01.006. PMID 15880325.
- ↑ Ivanyi B, Pap R, Ondrik Z (October 2006). "Thin basement membrane nephropathy: diffuse and segmental types". Arch. Pathol. Lab. Med. 130 (10): 1533–7. doi:10.1043/1543-2165(2006)130[1533:TBMNDA]2.0.CO;2. PMID 17090197.
- ↑ "Redirecting".