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==Overview== | ==Overview== | ||
'''Scurvy''' is a chronic [[deficiency disease]] of [[vitamin C]], which is necessary for normal [[collagen]] formation in humans. L-ascorbic acid, the scientific name for vitamin c, is derived from the Latin name, scorbutus. Early symptoms of this disease are fatigue, weakness, and sore arms and legs. Without treatment, changes in [[hair]], [[skin]], and [[gums]] occur. <ref name="pmid25983516">{{Cite pmid|25983516}}</ref> As scurvy worsens there can be [[personality changes]], poor [[wound healing]] and ultimately leading to death due to [[bleeding]] or [[infection]]. <ref name="pmid11">{{Cite pmid|11}}</ref> | |||
Previously, this disease was common among pirates, sailors, and all others who were separated from the resources of vitamin c e.g. [[fruits]] and [[vegetables]] for extended periods. It takes a month with low or no vitamin c to cause symptoms. <ref name="pmid1">{{Cite pmid|1}}</ref> | |||
In infants, scurvy is sometimes referred to as '''Barlow's disease''', named after Sir [[Thomas Barlow]] (1845–1945), <ref name="pmid6423046">{{Cite pmid|6423046}}</ref> a British [[physician]] who described it. Other eponyms include '''Moeller's disease''' and '''Cheadle's disease'''. | |||
==Pathophysiology== | ==Pathophysiology== | ||
Revision as of 16:37, 3 June 2020
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
Scurvy is a chronic deficiency disease of vitamin C, which is necessary for normal collagen formation in humans. L-ascorbic acid, the scientific name for vitamin c, is derived from the Latin name, scorbutus. Early symptoms of this disease are fatigue, weakness, and sore arms and legs. Without treatment, changes in hair, skin, and gums occur. [1] As scurvy worsens there can be personality changes, poor wound healing and ultimately leading to death due to bleeding or infection. [2] Previously, this disease was common among pirates, sailors, and all others who were separated from the resources of vitamin c e.g. fruits and vegetables for extended periods. It takes a month with low or no vitamin c to cause symptoms. [3] In infants, scurvy is sometimes referred to as Barlow's disease, named after Sir Thomas Barlow (1845–1945), [4] a British physician who described it. Other eponyms include Moeller's disease and Cheadle's disease.
Pathophysiology
Physiology
Pathogenesis
Genetics
Associated Conditions
Gross Pathology
Microscopic Pathology
References
- ↑ PMID 25983516 (PMID 25983516)
Citation will be completed automatically in a few minutes. Jump the queue or expand by hand - ↑ PMID 11 (PMID 11)
Citation will be completed automatically in a few minutes. Jump the queue or expand by hand - ↑ PMID 1 (PMID 1)
Citation will be completed automatically in a few minutes. Jump the queue or expand by hand - ↑ PMID 6423046 (PMID 6423046)
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