Desmoid tumor diagnostic study of choice: Difference between revisions
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==Overview== | ==Overview== | ||
==Diagnostic study of choice== | ==Diagnostic study of choice== | ||
*Biopsy is the most important and conclusive diagnostic procedure for desmoid tumor | |||
*After biopsy, electron microscopy is performed to obtain further clarity and confirmation for the diagnosis | |||
*Spindle cells of desmoid tumors appear to be myofibroblasts on electron microscopy which represents an abnormal proliferation of myofibroblasts, which normally disappear gradually during the later stages of wound healing | |||
*Immunohistochemical stains are done to look for nuclear accumulation of beta-catenin | |||
*Regardless of the site, 90% of desmoids show nuclear reactivity (has relatively high specificity) | |||
Revision as of 19:52, 28 February 2019
Overview
Diagnostic study of choice
- Biopsy is the most important and conclusive diagnostic procedure for desmoid tumor
- After biopsy, electron microscopy is performed to obtain further clarity and confirmation for the diagnosis
- Spindle cells of desmoid tumors appear to be myofibroblasts on electron microscopy which represents an abnormal proliferation of myofibroblasts, which normally disappear gradually during the later stages of wound healing
- Immunohistochemical stains are done to look for nuclear accumulation of beta-catenin
- Regardless of the site, 90% of desmoids show nuclear reactivity (has relatively high specificity)