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==Classification==
==Classification==
* Epithelial ovarian tumors can broadly be classified on the bases of histopathology and clinical behavior as:
* '''Epithelial ovarian tumors''' can broadly be classified on the bases of histopathology and clinical behavior as:
** Benign
** Benign
** Borderline
** Borderline
** Malignant tumors
** Malignant tumors


* Table below provides a summary of this classification:
* '''Table''' below provides a summary of this classification:
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* '''Transitional cell tumors'''
* '''Transitional cell tumors'''
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* WHO classifies epithelial ovarian tumors as follows:
* '''WHO''' classifies epithelial ovarian tumors on the basis of histology as follows:
* '''Serous tumors:'''
** '''Serous tumors:'''
** Benign (cystadenoma)
*** Benign (cystadenoma)
** Borderline tumors (serous borderline tumor)
*** Borderline tumors (serous borderline tumor)
** Malignant (serous adenocarcinoma)
*** Malignant (serous adenocarcinoma)
* '''Mucinous tumors:'''
** '''Mucinous tumors:'''
** Benign (cystadenoma)
*** Benign (cystadenoma)
** Borderline tumors (mucinous borderline tumor)
*** Borderline tumors (mucinous borderline tumor)
** Malignant (mucinous adenocarcinoma)
*** Malignant (mucinous adenocarcinoma)
* '''Endometrioid tumors:'''
** '''Endometrioid tumors:'''
** Benign (cystadenoma)
*** Benign (cystadenoma)
** Borderline tumors (endometrioid borderline tumor)
*** Borderline tumors (endometrioid borderline tumor)
** Malignant (endometrioid adenocarcinoma)
*** Malignant (endometrioid adenocarcinoma)
* '''Clear cell tumors:'''
** '''Clear cell tumors:'''
** Benign
*** Benign
** Borderline tumors
*** Borderline tumors
** Malignant (clear cell adenocarcinoma)
*** Malignant (clear cell adenocarcinoma)
* '''Transitional cell tumors:'''
** '''Transitional cell tumors:'''
** Brenner tumor
*** Brenner tumor
** Brenner tumor of borderline malignancy
*** Brenner tumor of borderline malignancy
** Malignant Brenner tumor
*** Malignant Brenner tumor
** Transitional cell carcinoma (non-Brenner type)
*** Transitional cell carcinoma (non-Brenner type)
* '''Epithelial-stromal:'''
** '''Epithelial-stromal:'''
** Adenosarcoma
*** Adenosarcoma
** Carcinosarcoma (formerly mixed Müllerian tumors)
*** Carcinosarcoma (formerly mixed Müllerian tumors)
** Recent advances in histopathology and a better understanding of clinicopathologic characteristics have led to a classification system that correlates histology and clinical characteristics;
**
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! colspan="2" |Epithelial Ovarian Cancer
! colspan="2" |Epithelial Ovarian Cancer
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!Type 1
!Type I
!Type 2
!Type II
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Revision as of 16:33, 13 February 2019


Template:Eithelial Ovarian Cancers Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Hannan Javed, M.D.[2]

Overview

Classification

  • Epithelial ovarian tumors can broadly be classified on the bases of histopathology and clinical behavior as:
    • Benign
    • Borderline
    • Malignant tumors
  • Table below provides a summary of this classification:
Epithelial ovarian tumors
Benign Borderline Malignant
  • Serous tumors
  • Mucinous tumors
  • Endometrioid tumors
  • Clear cell tumors
  • Serous tumors
  • Mucinous tumors
  • Endometrioid tumors
  • Clear cell tumors
  • Transitional cell tumors
  • Serous tumors
  • Mucinous tumors
  • Endometrioid tumors
  • Clear cell tumors
  • Transitional cell tumors
  • WHO classifies epithelial ovarian tumors on the basis of histology as follows:
    • Serous tumors:
      • Benign (cystadenoma)
      • Borderline tumors (serous borderline tumor)
      • Malignant (serous adenocarcinoma)
    • Mucinous tumors:
      • Benign (cystadenoma)
      • Borderline tumors (mucinous borderline tumor)
      • Malignant (mucinous adenocarcinoma)
    • Endometrioid tumors:
      • Benign (cystadenoma)
      • Borderline tumors (endometrioid borderline tumor)
      • Malignant (endometrioid adenocarcinoma)
    • Clear cell tumors:
      • Benign
      • Borderline tumors
      • Malignant (clear cell adenocarcinoma)
    • Transitional cell tumors:
      • Brenner tumor
      • Brenner tumor of borderline malignancy
      • Malignant Brenner tumor
      • Transitional cell carcinoma (non-Brenner type)
    • Epithelial-stromal:
      • Adenosarcoma
      • Carcinosarcoma (formerly mixed Müllerian tumors)
    • Recent advances in histopathology and a better understanding of clinicopathologic characteristics have led to a classification system that correlates histology and clinical characteristics;
Ovarian Cancer
Epithelial Sex-cord stromal Germ cell Mixed-cell type
  • Serous tumors:
    • Benign (cystadenoma)
    • Borderline tumors (serous borderline tumor)
    • Malignant (serous adenocarcinoma)
  • Mucinous tumors:
    • Benign (cystadenoma)
    • Borderline tumors (mucinous borderline tumor)
    • Malignant (mucinous adenocarcinoma)
  • Endometrioid tumors:
    • Benign (cystadenoma)
    • Borderline tumors (endometrioid borderline tumor)
    • Malignant (endometrioid adenocarcinoma)
  • Clear cell tumors:
    • Benign
    • Borderline tumors
    • Malignant (clear cell adenocarcinoma)
  • Transitional cell tumors:
    • Brenner tumor
    • Brenner tumor of borderline malignancy
    • Malignant Brenner tumor
    • Transitional cell carcinoma (non-Brenner type)
  • Epithelial-stromal:
    • Adenosarcoma
    • Carcinosarcoma (formerly mixed Müllerian tumors)
  • Pure stromal tumors:
    • Fibroma
    • Cellular fibroma
    • Thecoma
    • Luteinized thecoma associated with sclerosing peritonitis
    • Fibrosarcoma
    • Sclerosing stromal tumor
    • Signet-ring stromal tumor
    • Microcystic stromal tumor
    • Leydig cell tumor
    • Steroid cell tumor
    • Steroid cell tumor, malignant
  • Pure sex cord tumors:
    • Adult granulosa cell tumor
    • Juvenile granulosa cell tumor
    • Sertoli cell tumor
    • Sex cord tumor with annular tubules
  • Mixed sex cord-stromal tumors
    • Sertoli-Leydig cell tumors
      • - Well-differentiated
      • - Moderately differentiated with heterologous elements
      • - Poorly differentiated with heterologous elements
      • - Retiform with heterologous elements
    • Sex cord-stromal tumours, NOS*
  • Teratoma
    • Immature
    • Mature
    • Solid
    • Cystic (dermoid cyst)
  • Dysgerminoma
  • Endometrial Sinus tumors
  • Embryonal carcinoma
  • Polyembryoma
  • Choriocarcinoma
  • Mixed germ cell tumors tumors
Epithelial Ovarian Cancer
Type I Type II
  • Low-grade serous carcinoma
  • Endometrioid carcinoma
  • Clear cell carcinoma
  • Mucinous carcinoma
  • Malignant Brenner tumor
  • Seromucinous carcinoma
  • High-grade serous carcinoma
  • Undifferentiated carcinoma
  • Carcinosarcoma

References

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