Sandbox:Trusha

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Trusha Tank, M.D.[2]

Diseases	Clinical manifestations						Para-clinical findings						Gold standard	Additional findings
	Symptoms				Physical exam
							Lab Findings		Radiology			Histopathology
	Cough and Sputum	Hemoptysis	Weight loss	Other	Percussion	Auscultation	CBC	Sputum analysis	Nodule	Nodule content	Other findings
Pulmonary Nodule(benign)	-	-	-	Asymptomatic	Hyporesonance Dull percussion	Normal Present pleural friction rub Present egophony Crackling or bubbling noises Present whispered pectoriloquy Decreased/absent breath sounds	Normal	Normal	Single Round, oval <5 mm nodule Ground glass	Fat in nodule Calcification Central dense nidus Diffuse solid Laminated Popcorn	well-defined smooth border Growth rate over 18 months Cavity wall thickness of 1 mm	N/A	N/A	↓ O2 Sat
Pulmonary Nodule (malignant)	++	++	++	Dyspnea Non resolving pneumonia Wheezing Chest pain Cachexia Fatigue Loss of appetite Dysphonia Dysphagia	Hyporesonance Dull percussion	Normal Present pleural friction rub Present egophony Crackling or bubbling noises Present whispered pectoriloquy Decreased/absent breath sounds	Normal	Sputum cytology Tumor cells	Multiple small Single > 2 cm of size	Calcification Amorphous Punctate Reticular Stippled or eccentric Cavity Ulceration	Spiculated border Rapid growth rate (Doubling time 1-18 months) Cavity wall thickness over 15 mm	central necrosis Cavity lined by viable cancer cells without necrosis	Biopsy and histopathological analysis	↓ O2 Sat
Diseases	Cough/Sputum	Hemoptysis	Weight loss	Other symptoms	Percussion	Auscultation	CBC	Sputum analysis	Nodule	Content	Other findings	Histopathology	Gold standard	Additional findings
Abscess	++	-	-	High fever (> 101' F) Pleuritic chest pain	Dull percussion	Decreased breath sound Bronchial breath sound Inspiratory crackles Localised crepitations	Pronounced leukocytosis >15,000 WBC/microliter Anemia of chronic disease	Sputum analysis and culture Causative agents						Clubbing of finger
Septic emboli
Fungi
Parasites
Mycobacterial infections
Chronic inflammatory conditions
Diseases	Cough/Sputum	Cough/Sputum	Weight loss	Other symptoms	Percussion	Auscultation	CBC	Sputum analysis	Chest X-ray	CT scan	Other imaging	Histopathology	Gold standard	Additional findings
Pulmonary AVMs
Pneumoconioses