| '''NIMA (never in mitosis gene a)-related kinase 1''', also known as '''NEK1''', is a human [[gene]] highly expressed in [[germ cells]] and thought to be involved in [[meiosis]]. It is also involved in the response to [[DNA damage]] from radiation; defects in this gene can be a cause of [[polycystic kidney disease]].<ref name="entrez">{{cite web|url=https://www.ncbi.nlm.nih.gov/gene/4750|title=NEK1 NIMA related kinase 1 [Homo sapiens (human)] - Gene - NCBI|publisher=|accessdate=28 July 2016}}</ref> NEK1 is thought to be involved in [[amytrophic lateral sclerosis]].<ref>{{Cite web|url=http://www.bbc.com/news/health-36901867|title=Ice Bucket Challenge funds gene discovery in ALS (MND) research - BBC News|last=|first=|date=2016-07-27|website=|publisher=BBC|language=en-GB|access-date=2016-07-27}}</ref><ref>{{cite journal | vauthors = Kenna KP, van Doormaal PT, Dekker AM, Ticozzi N, Kenna BJ, Diekstra FP, van Rheenen W, van Eijk KR, Jones AR, Keagle P, Shatunov A, Sproviero W, Smith BN, van Es MA, Topp SD, Kenna A, Miller JW, Fallini C, Tiloca C, McLaughlin RL, Vance C, Troakes C, Colombrita C, Mora G, Calvo A, Verde F, Al-Sarraj S, King A, Calini D, de Belleroche J, Baas F, van der Kooi AJ, de Visser M, Ten Asbroek AL, Sapp PC, McKenna-Yasek D, Polak M, Asress S, Muñoz-Blanco JL, Strom TM, Meitinger T, Morrison KE, Lauria G, Williams KL, Leigh PN, Nicholson GA, Blair IP, Leblond CS, Dion PA, Rouleau GA, Pall H, Shaw PJ, Turner MR, Talbot K, Taroni F, Boylan KB, Van Blitterswijk M, Rademakers R, Esteban-Pérez J, García-Redondo A, Van Damme P, Robberecht W, Chio A, Gellera C, Drepper C, Sendtner M, Ratti A, Glass JD, Mora JS, Basak NA, Hardiman O, Ludolph AC, Andersen PM, Weishaupt JH, Brown RH, Al-Chalabi A, Silani V, Shaw CE, van den Berg LH, Veldink JH, Landers JE | display-authors = 6 | title = NEK1 variants confer susceptibility to amyotrophic lateral sclerosis | journal = Nature Genetics | date = July 2016 | pmid = 27455347 | doi = 10.1038/ng.3626 | volume=48 | pages=1037–42}}</ref> | | '''NIMA (never in mitosis gene a)-related kinase 1''', also known as '''NEK1''', is a human [[gene]] highly expressed in [[germ cells]] and thought to be involved in [[meiosis]]. It is also involved in the response to [[DNA damage]] from radiation; defects in this gene can be a cause of [[polycystic kidney disease]].<ref name="entrez">{{cite web|url=https://www.ncbi.nlm.nih.gov/gene/4750|title=NEK1 NIMA related kinase 1 [Homo sapiens (human)] - Gene - NCBI|publisher=|accessdate=28 July 2016}}</ref> NEK1 is thought to be involved in [[amytrophic lateral sclerosis]].<ref>{{Cite web|url=https://www.bbc.com/news/health-36901867|title=Ice Bucket Challenge funds gene discovery in ALS (MND) research - BBC News|last=|first=|date=2016-07-27|website=|publisher=BBC|language=en-GB|access-date=2016-07-27}}</ref><ref>{{cite journal | vauthors = Kenna KP, van Doormaal PT, Dekker AM, Ticozzi N, Kenna BJ, Diekstra FP, van Rheenen W, van Eijk KR, Jones AR, Keagle P, Shatunov A, Sproviero W, Smith BN, van Es MA, Topp SD, Kenna A, Miller JW, Fallini C, Tiloca C, McLaughlin RL, Vance C, Troakes C, Colombrita C, Mora G, Calvo A, Verde F, Al-Sarraj S, King A, Calini D, de Belleroche J, Baas F, van der Kooi AJ, de Visser M, Ten Asbroek AL, Sapp PC, McKenna-Yasek D, Polak M, Asress S, Muñoz-Blanco JL, Strom TM, Meitinger T, Morrison KE, Lauria G, Williams KL, Leigh PN, Nicholson GA, Blair IP, Leblond CS, Dion PA, Rouleau GA, Pall H, Shaw PJ, Turner MR, Talbot K, Taroni F, Boylan KB, Van Blitterswijk M, Rademakers R, Esteban-Pérez J, García-Redondo A, Van Damme P, Robberecht W, Chio A, Gellera C, Drepper C, Sendtner M, Ratti A, Glass JD, Mora JS, Basak NA, Hardiman O, Ludolph AC, Andersen PM, Weishaupt JH, Brown RH, Al-Chalabi A, Silani V, Shaw CE, van den Berg LH, Veldink JH, Landers JE | display-authors = 6 | title = NEK1 variants confer susceptibility to amyotrophic lateral sclerosis | journal = Nature Genetics | date = July 2016 | pmid = 27455347 | doi = 10.1038/ng.3626 | volume=48 | pages=1037–42}}</ref> |
