Pseudomyxoma peritonei history and symptoms: Difference between revisions

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Symptoms of pseudomyxoma peritonei include [[abdominal pain]], [[bloating]], [[abdominal distention]], weight changes, and [[infertility]].
Symptoms of pseudomyxoma peritonei include [[abdominal pain]], [[bloating]], [[abdominal distention]], weight changes, and [[infertility]].
==History==
==History==
PMP is typically diagnosed between the ages of 40-55, and is often found incidentally in patients undergoing laparotomy, laparoscopy, or imaging for other medical conditions. Due to its indolent nature and non-specific symptoms, most are found with advanced disease. The clinical presentation of the disease is dependent on the progression of the disease, as is the prognosis. Localized disease typically presents with appendicitis-like symptoms or a pelvic mass due to mucinous deposits on adjacent organs. More advanced disease presents with abdominal distension, bowel obstruction, and ascites. The classic sign termed “jelly belly” is an increase in abdominal girth caused by an accumulation of gelatinous ascites.<ref name="pmid17511043">{{cite journal |vauthors=Dixit A, Robertson JH, Mudan SS, Akle C |title=Appendiceal mucocoeles and pseudomyxoma peritonei |journal=World J. Gastroenterol. |volume=13 |issue=16 |pages=2381–4 |date=April 2007 |pmid=17511043 |pmc=4147153 |doi= |url=}}</ref>
PMP is typically diagnosed between the ages of 40-55, and is often found incidentally in patients undergoing abdominal surgery or imaging for other medical conditions. Due to its indolent nature and non-specific symptoms, most are found with advanced disease. The clinical presentation of the disease is dependent on the progression of the disease, as is the prognosis. Localized disease typically presents with appendicitis-like symptoms or a pelvic mass due to mucinous deposits on adjacent organs. More advanced disease presents with abdominal distension, bowel obstruction, and ascites. The classic sign termed “jelly belly” is an increase in abdominal girth caused by an accumulation of gelatinous ascites.<ref name="pmid17511043">{{cite journal |vauthors=Dixit A, Robertson JH, Mudan SS, Akle C |title=Appendiceal mucocoeles and pseudomyxoma peritonei |journal=World J. Gastroenterol. |volume=13 |issue=16 |pages=2381–4 |date=April 2007 |pmid=17511043 |pmc=4147153 |doi= |url=}}</ref>


==Symptoms==
==Symptoms==

Revision as of 15:50, 7 January 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Parminder Dhingra, M.D. [2]

Overview

Symptoms of pseudomyxoma peritonei include abdominal pain, bloating, abdominal distention, weight changes, and infertility.

History

PMP is typically diagnosed between the ages of 40-55, and is often found incidentally in patients undergoing abdominal surgery or imaging for other medical conditions. Due to its indolent nature and non-specific symptoms, most are found with advanced disease. The clinical presentation of the disease is dependent on the progression of the disease, as is the prognosis. Localized disease typically presents with appendicitis-like symptoms or a pelvic mass due to mucinous deposits on adjacent organs. More advanced disease presents with abdominal distension, bowel obstruction, and ascites. The classic sign termed “jelly belly” is an increase in abdominal girth caused by an accumulation of gelatinous ascites.[1]

Symptoms

Symptoms of pseudomyxoma peritonei may include:[2]

  • Abdominal or pelvic pain
  • New-onset hernia[3]
  • Bloating
  • Abdominal distension
  • Weight change
  • Increased abdominal girth.
  • Appendicitis-like symptoms in some cases.[4]
  • Gynecological complaints in females such as menstrual irregularity due to the ovarian deposits of the mucinous tumor.
  • Subcutaneous non tender umbilical nodule have also been reported in rare cases.[5]

References

  1. Dixit A, Robertson JH, Mudan SS, Akle C (April 2007). "Appendiceal mucocoeles and pseudomyxoma peritonei". World J. Gastroenterol. 13 (16): 2381–4. PMC 4147153. PMID 17511043.
  2. Esquivel J, Sugarbaker PH (October 2000). "Clinical presentation of the Pseudomyxoma peritonei syndrome". Br J Surg. 87 (10): 1414–8. doi:10.1046/j.1365-2168.2000.01553.x. PMID 11044169.
  3. Gomes C, Tenreiro N, Marçal A, Moreira H, Pinto B, Avelar P (July 2018). "Pseudomyxoma peritonei presenting as irreducible epigastric hernia". J Surg Case Rep. 2018 (7): rjy148. doi:10.1093/jscr/rjy148. PMC 6044295. PMID 30026907.
  4. Smeenk RM, Verwaal VJ, Zoetmulder FA (February 2007). "[Pseudomyxoma peritonei; a rare tumour that can be treated with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy]". Ned Tijdschr Geneeskd (in Dutch; Flemish). 151 (7): 418–23. PMID 17343142.
  5. Srinivasaiah N, Retnasingam G, Kasarneni R, Slater B (June 2009). "Pseudomyxoma peritonei: a rare presentation as an umbilical nodule". Ir J Med Sci. 178 (2): 219–21. doi:10.1007/s11845-008-0118-2. PMID 18224368.


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