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==Natural History, Complications and Prognosis== | ==Natural History, Complications and Prognosis== | ||
* Common complications of include sever fatal bleeding following major surgeries , labor and delivery. | |||
* 84% of patients with Glanzmann’s thrombasthenia require at least once in their life red blood cell transfusion. | |||
* the episodes of severe spontaneous hemorrhage is reduced with age. | |||
* The of the bleeding episodes in can vary greatly among affected individuals, even in the same family. | |||
* Patients with Glanzmann thrombasthenia, even the individuals of the same family and ethnicity manifest diverse bleeding frequency tendency and severity and even within the same family or ethnic group | |||
* In patients with Glanzmann’s thrombasthenia, the quality of life of is influenced by several mucocutaneous hemorrhages and heavy bleeding in various conditions such as menstruation,trauma and surgery . | |||
* Prognosis is generally excellent with good supportive care and the mortality rate of patients with Glanzmann’s thrombasthenia is relatively low.<ref name="pmid26185478">{{cite journal| author=Solh T, Botsford A, Solh M| title=Glanzmann's thrombasthenia: pathogenesis, diagnosis, and current and emerging treatment options. | journal=J Blood Med | year= 2015 | volume= 6 | issue= | pages= 219-27 | pmid=26185478 | doi=10.2147/JBM.S71319 | pmc=4501245 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26185478 }}</ref> | |||
==References== | ==References== |
Revision as of 05:15, 19 July 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Natural History, Complications and Prognosis
- Common complications of include sever fatal bleeding following major surgeries , labor and delivery.
- 84% of patients with Glanzmann’s thrombasthenia require at least once in their life red blood cell transfusion.
- the episodes of severe spontaneous hemorrhage is reduced with age.
- The of the bleeding episodes in can vary greatly among affected individuals, even in the same family.
- Patients with Glanzmann thrombasthenia, even the individuals of the same family and ethnicity manifest diverse bleeding frequency tendency and severity and even within the same family or ethnic group
- In patients with Glanzmann’s thrombasthenia, the quality of life of is influenced by several mucocutaneous hemorrhages and heavy bleeding in various conditions such as menstruation,trauma and surgery .
- Prognosis is generally excellent with good supportive care and the mortality rate of patients with Glanzmann’s thrombasthenia is relatively low.[1]
References
- ↑ Solh T, Botsford A, Solh M (2015). "Glanzmann's thrombasthenia: pathogenesis, diagnosis, and current and emerging treatment options". J Blood Med. 6: 219–27. doi:10.2147/JBM.S71319. PMC 4501245. PMID 26185478.