Paroxysmal nocturnal hemoglobinuria other diagnostic studies: Difference between revisions

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==Other Diagnostic Studies==
==Other Diagnostic Studies==


[Flow cytometry] is the preferred diagnostic study to confirm or to rule out PNH after verifying . Findings diagnostic of [PNH] include:
*[Flow cytometry] is the diagnostic study of choice to confirm or exclude PNH, but has to be performed only after confirming coomb's negative intravascular hemolysis. Findings include reduced levels or absent glycosylphosphatidylinositol (GPI) linked proteins on surface of blood cells. Commonly detected GPI linked proteins include CD59 and CD55.
* reduced levels of GPI- proteins on surface of blood cells
*[Finding 2]
*[Finding 3]


OR
*Other diagnostic studies not required for diagnosis include:
 
*#[Bone marrow biopsy]
Other diagnostic studies for [disease name] include:
*#*Indication: Pancytopenia
*[Diagnostic study 1], which demonstrates:
*#*Findings: hypocellular or normocellular or hypercellular marrow
**[Finding 1]
**[Finding 2]
**[Finding 3]
*[Diagnostic study 2], which demonstrates:  
**[Finding 1]
**[Finding 2]
**[Finding 3]


==References==
==References==

Revision as of 01:49, 12 July 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

There are no other diagnostic studies associated with [disease name].

OR

[Diagnostic study] may be helpful in the diagnosis of [disease name]. Findings suggestive of/diagnostic of [disease name] include [finding 1], [finding 2], and [finding 3].

OR

Other diagnostic studies for [disease name] include [diagnostic study 1], which demonstrates [finding 1], [finding 2], and [finding 3], and [diagnostic study 2], which demonstrates [finding 1], [finding 2], and [finding 3].

Other Diagnostic Studies

  • [Flow cytometry] is the diagnostic study of choice to confirm or exclude PNH, but has to be performed only after confirming coomb's negative intravascular hemolysis. Findings include reduced levels or absent glycosylphosphatidylinositol (GPI) linked proteins on surface of blood cells. Commonly detected GPI linked proteins include CD59 and CD55.
  • Other diagnostic studies not required for diagnosis include:
    1. [Bone marrow biopsy]
      • Indication: Pancytopenia
      • Findings: hypocellular or normocellular or hypercellular marrow

References

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