Lead poisoning differential diagnosis: Difference between revisions

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Revision as of 12:17, 17 June 2018

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aksiniya K. Stevasarova, MD

Overview

Lead poisoning must be differentiated from megaloblastic anemia, carpal tunnel syndrome, Guillain–Barré syndrome, renal colic, appendicitis, encephalitis in adults, and viral gastroenteritis in children.^[1], constipation, abdominal colic, iron deficiency, subdural hematoma, neoplasms of the central nervous system, emotional and behavior disorders, and intellectual disability.^[2]

Differentiating Lead poisoning from other Diseases

As lead poisoning manifests in a variety of clinical forms, differentiation must be established in accordance with the particular clinical symptom. For example sideroblastic anemia must be differentiated from other diseases that cause basophilic stippling like megaloblastic anemia.

Preferred Table

	Symptoms			Physical examination			Lab Findings			Imaging			Histopathology
Diseases	Clinical manifestations						Para-clinical findings							Gold standard	Additional findings
	Symptoms			Physical examination			Para-clinical findings
	Symptom 1	Symptom 2	Symptom 3	Physical exam 1	Physical exam 2	Physical exam 3	Lab 1	Lab 2	Lab 3	Imaging 1	Imaging 2	Imaging 3	Histopathology
Megaloblastic anemia
Guillain–Barré syndrome
Encephalitis
Diseases	Symptom 1	Symptom 2	Symptom 3	Physical exam 1	Physical exam 2	Physical exam 3	Lab 1	Lab 2	Lab 3	Imaging 1	Imaging 2	Imaging 3	Histopathology	Gold standard	Additional findings
Intellectual disability
Constipation
Viral gastroenteritis

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[Henretig061316-1] ↑

[Mycyk05-463-2] ↑

[1]

[2]

@@ Line 4: / Line 4: @@
 ==Overview==
-[[Lead poisoning]] must be differentiated from [[megaloblastic anemia]], [[carpal tunnel syndrome]], [[Guillain–Barré syndrome]], [[renal colic]], [[appendicitis]], [[encephalitis]] in adults, and [[viral gastroenteritis]] in children.<ref name="Henretig061316"/>, [[constipation]], abdominal colic, iron deficiency, [[subdural hematoma]], [[neoplasm]]s of the central nervous system, emotional and behavior disorders, and [[intellectual disability]].<ref name="Mycyk05-463"/>
+[[Lead poisoning]] must be differentiated from [[megaloblastic anemia]], [[carpal tunnel syndrome]], [[Guillain–Barré syndrome]], [[renal colic]], [[appendicitis]], [[encephalitis]] in adults, and [[viral gastroenteritis]] in children.<ref name="Henretig061316"/>, [[constipation]], [[abdominal colic]], [[iron deficiency]], [[subdural hematoma]], [[neoplasms of the central nervous system]], emotional and behavior disorders, and [[intellectual disability]].<ref name="Mycyk05-463"/>
 ==Differentiating [[Lead poisoning]] from other Diseases==
@@ Line 38: / Line 38: @@
 ! style="background: #4479BA; color: #FFFFFF; text-align: center;|Imaging 3
 |-
-| style="background: #DCDCDC; padding: 5px; text-align: center;" |Differential Diagnosis 1
+| style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Megaloblastic anemia]]
 | style="background: #F5F5F5; padding: 5px;" |
 | style="background: #F5F5F5; padding: 5px;" |
@@ Line 55: / Line 55: @@
 | style="background: #F5F5F5; padding: 5px;" |
 |-
-| style="background: #DCDCDC; padding: 5px; text-align: center;" |Differential Diagnosis 2
+| style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Guillain–Barré syndrome]]
 | style="background: #F5F5F5; padding: 5px;" |
 | style="background: #F5F5F5; padding: 5px;" |
@@ Line 72: / Line 72: @@
 | style="background: #F5F5F5; padding: 5px;" |
 |-
-| style="background: #DCDCDC; padding: 5px; text-align: center;" |Differential Diagnosis 3
+| style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Encephalitis]]
 | style="background: #F5F5F5; padding: 5px;" |
 | style="background: #F5F5F5; padding: 5px;" |
@@ Line 106: / Line 106: @@
 !Additional findings
 |-
-| style="background: #DCDCDC; padding: 5px; text-align: center;" |Differential Diagnosis 4
+| style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Intellectual disability]]
 | style="background: #F5F5F5; padding: 5px;" |
 | style="background: #F5F5F5; padding: 5px;" |
@@ Line 123: / Line 123: @@
 | style="background: #F5F5F5; padding: 5px;" |
 |-
-| style="background: #DCDCDC; padding: 5px; text-align: center;" |Differential Diagnosis 5
+| style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Constipation]]
 | style="background: #F5F5F5; padding: 5px;" |
 | style="background: #F5F5F5; padding: 5px;" |
@@ Line 140: / Line 140: @@
 | style="background: #F5F5F5; padding: 5px;" |
 |-
-| style="background: #DCDCDC; padding: 5px; text-align: center;" |Differential Diagnosis 6
+| style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Viral gastroenteritis]]
 | style="background: #F5F5F5; padding: 5px;" |
 | style="background: #F5F5F5; padding: 5px;" |

Lead poisoning differential diagnosis: Difference between revisions

Revision as of 12:17, 17 June 2018

Overview

Differentiating Lead poisoning from other Diseases

Preferred Table

References

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